Abstract
Jerina commented that he has observed binding of the diol-epoxide of benzo [a] pyrene to polyguanylic acid and found that it binds extensively. Miller suggested to Jerina that it was probably an example of O-6 alkylation. Brookes reported that binding with benzo [a] pyrene and 7-methylbenzanthracene in vivo involves a purine. He has observed hydrocarbon binding to purine but not pyrimidine moieties.
Keywords
Tumor Cell Gene Action Direct Interaction Indirect Evidence Immunosuppressive Agent
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Copyright information
© Plenum Press, New York 1977