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The Physiological Role of the Silicon and its AntiAtheromatous Action

  • J. Loeper
  • J. Loeper
  • M. Fragny
Chapter
Part of the Nobel Foundation Symposia book series (NOFS, volume 40)

Summary

In human atherosclerosis, the concentration of silicon in the aortic wall decreases and this decrease precedes the appearence of lipid deposits. This stimulated study of the antiatheroma action of silicon in atherosclerosis experimentally produced by cholesterol.

Silicon partially inhibits lipid deposition by maintaining the normal caliber of elastic fibres, with occasional thickening and proliferation of these fibres. It also conserves the integrity of mucopolysaccharides and heightens the impermeability of the endothelium, resulting in a reduced penetration of lipids.

Keywords

Sodium Silicate Elastic Fibre Cholesterol Diet Fatty Infiltration Sodium Salicylate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • J. Loeper
    • 1
    • 2
  • J. Loeper
    • 1
    • 3
  • M. Fragny
    • 1
  1. 1.Clinique No. 1Hôpital de la SalpêtrièreParisFrance
  2. 2.Faculté de Médecine de ParisFrance
  3. 3.ParisFrance

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