Vitamin D pp 217-232 | Cite as

Vitamin D Metabolism During Pregnancy

  • T. Kenney Gray
Chapter

Abstract

In the non-pregnant state the serum concentration of 25-hydroxyvitamin D (25-OHD) varies according to the season of the year, the geographic location and the dietary intake of vitamin D (1). The serum concentration of 25-OHD is regarded as a measure of the vitamin D status in the absence of intestinal or hepatic disease. A dietary deficiency of vitamin D or a limited exposure of the skin to sunlight would be associated with a low serum level of 25-OHD (1). In pregnant residents of mid-western U.S.A. and of mixed ethnic origin, the major determinant of the 25-OHD concentration in serum is exposure to sunlight (2). Varied sunlight exposure is the common denominator in the seasonal and geographic variation in the serum concentration of 25-OHD. The ultraviolet radiation of sunlight stimulates the cutaneous synthesis of vitamin D3 (3). When exposure to sunlight and the dietary content of vitamin D are taken into account, the serum concentration of 25-OHD during pregnancy is no different than the values observed in non-pregnant subjects (2,4,5). As expected, whenever the dietary intake of vitamin D or the exposure to sunlight is restricted during pregnancy, the serum concentration of 25-OHD is lower (6,7).

Keywords

Intestinal Calcium Absorption Ovine Placenta Excerpta Medica International Congress Series Pregnant Resident Intestinal CaBP 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Martinus Nijhoff Publishing, Boston/The Hague/Dordrecht/Lancaster 1984

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  • T. Kenney Gray

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