Biology of Brain Tumour pp 349-354 | Cite as
252CF Neutron brachytherapy for malignant glioma at the University of Kentucky and a malignant glioma therapeutic staging system
Chapter
Abstract
Cf-252 is a transplutonium radioactive isotope which emits fast neutrons and is useful for human malignant glioma implant therapy. The early trials have led to evolution of methods. A proposed therapeutic staging system, using MRI and CT imaging, for hemispheric malignant astrocytomas and glioblastoma multiforme is described.
Keywords
Glial Fibrillary Acidic Protein Malignant Glioma Glioblastoma Multiforme Fast Neutron Anaplastic Astrocytoma
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- 1.Maruyama Y, Chin HW, Young AB, Beach JL, Bean J, Tibbs P: 252 Cf neutron brachytherapy for hemispheric malignant glioma. Radiol 145: 171–4, 1982Google Scholar
- 2.Gray LH, Conger AB, Ebert M, Hornsey S, Scott OCA: The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Brit J Radiol 26: 638–48, 1953PubMedCrossRefGoogle Scholar
- 3.Maruyama Y: Cf-252 Neutron Brachytherapy, Advance for bulky localized cancer therapy. Nucl Sci Appl 1: 677–748, 1984Google Scholar
- 4.Cattcrall M, Bloom HJ, Ash DV et al.: Fast neutrons compared with megavoltage x-rays in the treatment of patients with supratentorial glioblastoma; a controlled pilot study. Int J Rad Oncol Biol Phys 6: 261–6, 1980CrossRefGoogle Scholar
- 5.Parker RG, Berry HC, Gerdes A, et al.: Fast neutrons beam radiotherapy of glioblastoma multiforme. Am J Roent 127: 331–5, 1976Google Scholar
- 6.Maruyama Y, Chin HW, Young AB, Wang PC, Tibbs P, Beach JL, Goldstein S: Implantation of brain tumors with Cf-252: use of CT & MR to guide insertion and evaluate response. Radiol 152: 177–81, 1984Google Scholar
- 7.Maruyama Y, Chin HW, Young AB, Beach JL, Tibbs P, Goldstein S, Markesbery W: CT & MR for brain tumor implant therapy using Cf-252 neutrons. J Neuro Oncol 2: 349–360, 1984CrossRefGoogle Scholar
- 8.Sheline GD: The importance of distinguishing tumor grade in malignant glioma; Treatment and prognosis. Int J Rad Oncol Biol Phys 1: 781–6, 1976CrossRefGoogle Scholar
- 9.Walker MD, Green SB, Byar DP, et al.: Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. New Engl J Med 303: 1323–29, 1980PubMedCrossRefGoogle Scholar
- 10.Eng LF, DeArmond SJ: Glial Fibrillary Acid (GFA) Protein in development and neuropath. 11th Intl Cong of Anatomy: Glial and Neural cell biology. AR Liss (1981), pp 65–79Google Scholar
- 11.Deck JHN, Eng LF, Bigbee J, Woodcock SM: The role of glial fibrillary acidic protein in the diagnosis of central nervous system tumors. Acta Neuropath 42: 183–190. 1978PubMedCrossRefGoogle Scholar
- 12.Velasco ME, Dahl D, Roessmann U, Gambeth P: Immunohistochemical staining of glial fibrillary acidic protein in human glial neoplasms. Cancer 45: 484–494, 1980PubMedCrossRefGoogle Scholar
- 13.Van der Meulen JDM, Houthoff HJ, Ebels EJ: Glial fribrillary acidic protein in human gliomas. Neuropath Appl Neurobiol 4: 177–190, 1978CrossRefGoogle Scholar
- 14.Chin HW, Maruyama Y, Markesbery W, el al.: Early radiation changes of normal dog brain following internal and external brain irradiation. Proc Rad Res Soc 1984, p 108Google Scholar
Copyright information
© Martinas Nijhoff Publishers, Boston 1986