Avian Leukosis pp 153-169 | Cite as

Virus-Cell Interactions of Avian Sarcoma and Defective Leukemia Viruses

  • C. Moscovici
  • L. Gazzolo
Part of the Developments in Veterinary Virology book series (DVVI, volume 4)

Abstract

Avian retroviruses are able to induce malignant diseases, such as sarcoma, carcinoma and leukemia as well as non-malignant diseases, e.g. anemia or autoimmune diseases. In the field of cancerology, avian retroviruses have contributed greatly to elucidate some of the oncogenic processes. One main breakthrough was reached when it was shown that retroviruses induce malignant diseases through the action of cell-derived nucleotide sequences (referred to as oncogenes) either transduced in the genomic RNA, or activated by viral promoters (1,2).

Keywords

Chicken Embryo Rous Sarcoma Virus Hemopoietic Cell Histiocytic Sarcoma Avian Myeloblastosis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1986

Authors and Affiliations

  • C. Moscovici
    • 1
  • L. Gazzolo
    • 2
  1. 1.Tumor Virology Laboratory, Research Service, VAMC, and Department of PathologyCollege of Medicine, University of FloridaGainesvilleUSA
  2. 2.Laboratoire d’Epidémiologie et d’Immunovirologie des TumeursCNRS, Facultéde Médecine ACarrel, LyonFrance

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