Tumor Metastasis: Biology and Experimental Therapeutic Approaches

  • Luka Milas
  • Philip Tofilon
Chapter
Part of the Developments in Oncology book series (DION, volume 51)

Abstract

Establishment of metastatic growths is the final phase in the progression of malignant tumors; it is the outcome of many factors and processes involved at many steps in the journey of tumor cells from the primary tumor to new residing sites. Because currently available therapeutic modalities are usually unsuccessful in eradication of tumor metastases, it is this phase of tumor progression that concerns tumor therapists the most. Although there must be many other reasons for the inefficiency in the treatment of metastasis, insufficient knowledge of the biology of the metastatic process remains one of the major ones. By acquiring a better understanding of the processes involved in the spread of malignant tumors, it will be possible to design better preventive and therapeutic measures, ones successful at eliminating metastatic disease. Although research on tumor metastasis is relatively old, it has become more extensive during the past 10 to 15 years.

Keywords

Tumor Metastasis Cytotoxic Agent Sister Chromatid Exchange Metastasis Formation Spontaneous Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • Luka Milas
  • Philip Tofilon

There are no affiliations available

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