Perspectives for the Treatment of Gastrointestinal Tract Virus Infections

  • L. A. Babiuk
  • M. I. Sabara
  • P. Frenchick
Part of the Developments in Medical Virology book series (DIMV, volume 3)


Gastointestinal infections are one of the leading causes of morbidity and mortality in infants and young animals, both in developing and in developed countries. It has been estimated that between 3–10 billion cases of diarrhea occur annually in humans, resulting either directly or indirectly in approximately 10 million deaths (1,2). The largest number of deaths occur in the age group of 6–12 months, although diarrhea is a major factor in the health of children up to 5 years of age. The causes of acute diarrhea are often multifactorial being determined by nutritional and environmental conditions. For example, significant malnutrition may lead to an increased severity and duration of diarrhea. In addition to the nutritional component, the level of contamination of the environment by specific organisms has a significant effect on both incidence and mortality rate of the resulting diarrhea (3). It is estimated that malnurished children in unhygienic situations have a fatality rate of 6 deaths per 1000 cases of diarrhea presented for treatment (1).


Antiviral Drug Enteric Virus Gastrointestinal Infection Acute Diarrhea Antiviral Compound 
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Copyright information

© Martinus Nijhoff Publishing 1988

Authors and Affiliations

  • L. A. Babiuk
    • 1
  • M. I. Sabara
    • 1
  • P. Frenchick
    • 1
  1. 1.Veterinary Infectious Disease OrganizationSaskatoonCanada

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