The transphosphatidylation activity of phospholipase D

  • Chang-Hua Yu
  • Song-Yan Liu
  • Vincenzo Panagia
Part of the Developments in Molecular and Cellular Biochemistry book series (DMCB, volume 17)


Transphosphatidylation activity is a characteristic and remarkable property of phospholipase D (PLD) and has been studied in plants and mammalian tissues. This reaction is often used to confirm the properties and/or abnormalities of PLD activity. The mechanism for activating PLD transphosphatidylation seems multiple. Although significant changes of transphosphatidylation activity have been found in some pathological animal models, the biological significance of PLD transphosphatidylation remains largely unknown.

Key words

phospholipase D transphosphatidylation phosphatidylethanol phosphatidic acid signal transduction 


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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Chang-Hua Yu
    • 1
    • 2
  • Song-Yan Liu
    • 1
    • 2
  • Vincenzo Panagia
    • 1
    • 2
  1. 1.Division of Cardiovascular SciencesSt. Boniface General Hospital Research CentreWinnipegCanada
  2. 2.Departments of Physiology and Anatomy, Faculty of MedicineUniversity of ManitobaWinnipegCanada

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