Skip to main content

Treatment of Asthma in Children

  • Chapter
Current Review of Asthma
  • 178 Accesses

Abstract

Asthma is the most common chronic illness in children, affecting 6.9% of children younger than 18 years of age, or 5 million children in the United States [1]. It is the leading cause of school absenteeism, and leads to missed workdays in 36% of parents of school-age asthmatic patients [2]. Americans spend over 10 billion dollars each year on asthma, and as many as 50% of asthma patients spend more than 18% of their family income on asthma therapy [3]. Despite improvements in our understanding of asthma and in delivery systems for asthma medications, the incidence of asthma and of deaths due to asthma is rising. Asthma deaths have doubled for children 14 years of age and younger from 1979 to 1995, with the 50- to 14-year-old group driving this rise in mortality [4]. Asthma must be regarded as a potentially life-threatening disorder, even in mild cases; a recent population-based study in Victoria, British Columbia showed that the majority of asthma deaths occurred in patients who could not be classified as high risk [5]. Seventy-eight percent of parents of asthmatic patients report that asthma has a negative impact on their family; indeed, even in mild cases the disruption of family dynamics, school attendance, and social interactions can be significant [3].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References and Recommended Reading

  1. Adams PF, Marano MA: Number of selected reported chronic conditions, by age: U.S. 1994. Current Estimates from the National Health Interview Survey, 1994. Vital Health Stat 1995, 10:93–94.

    Google Scholar 

  2. Fowler MG, Davenport MG, Garg R: School functioning of US children with asthma. Pediatrics 1992, 90:939–944.

    PubMed  CAS  Google Scholar 

  3. White MV: Asthma in Children. In Conn’s Current Therapy. Edited by Rakel RE, Kersey R. Philadelphia; WB Saunders: 1999;764–773.

    Google Scholar 

  4. Surveillance for Asthma—US 1960–1995 (CDC Surveillance Summaries). MMWR 1998, 47(SS–l):l–26.

    Google Scholar 

  5. Robertson CF, Rubinfeld AR, Bowes G: Pediatric asthma deaths in Victoria: the mild are at risk. Pediatr Pulmonol 1992, 13:95–100.

    Article  PubMed  CAS  Google Scholar 

  6. National Heart, Lung and Blood Institute, National Asthma Education and Prevention Program: Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma. Bethesda, MD: National Institutes of Health, Pub. No. 97–4051; 1997.

    Google Scholar 

  7. White MV: Pathophysiology of asthma. In Current Review of Allergic Diseases. Edited by Kaliner MA. Philadelphia: Current Medicine; 1999:61–67.

    Google Scholar 

  8. American Academy of Allergy, Asthma and Immunology: Pediatric Asthma: Promoting Best Practices.http://www.aaaai.org/members/resources/initiatives/pediatricasth maguidelines/default.stm. Accessed September 5, 2002. The first version of pediatric asthma guidelines, and a must read for those caring for children.

  9. Yunginger JW, Reed CE, O’Connell EJ, et al.: A community-based study of the epidemiology of asthma. Incidence rates, 1964–1983. Am Rev Respir Dis 1992, 146:888–894.

    Article  PubMed  CAS  Google Scholar 

  10. Martinez EF, Wright AL, Taussig LM, et al.: Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 1995, 332:133–138.

    Article  PubMed  CAS  Google Scholar 

  11. Oswald H, Phelan PD, Lanigan A, et al.: Childhood asthma and lung function in mid-adult life. Pediatr Pulmonol 1997, 23:14–20.

    Article  PubMed  CAS  Google Scholar 

  12. Xuan W, Marks GB, Toelle BG, et al.: Risk factors for the onset and remission of atopy, wheeze, and airway hyperresponsiveness. Thorax 2002, 57:104–109. A population-based study following school-aged children with asthma into adulthood, offering evidence for remodeling occurring early in the life of a patient with persistent asthma.

    Article  PubMed  Google Scholar 

  13. Economides A, White MV: The treatment of asthma in children. Minority Health Today 2000, 1(4):10–19.

    Google Scholar 

  14. Bisgaard H: Delivery of inhaled medication to children. J Asthma 1997, 34(6):443–467. An excellent review of delivery devices, pros and cons.

    Article  PubMed  CAS  Google Scholar 

  15. Economides A, Kaliner MA: Asthma: diagnosis and management. Curr Pract Med 1999, 2(9):1719–1729.

    Google Scholar 

  16. Strachan DP, Wong J, Spector TD: Concordance and interrelationship of atopic diseases and markers of allergic sensitization among adult female twins. J Allergy Clin Immunol 2001, 108:901–907.

    Article  PubMed  CAS  Google Scholar 

  17. Nelson HS, Szefler SJ, Jacobs J, et al.: The relationships among environmental allergen sensitization, allergen exposure, pulmonary function and bronchial hyperresponsiveness in CAMP. J Allergy Clin Immunol 1999, 104:775–785. A good look at the relationship of asthma and allergens, from the CAMP database.

    Article  PubMed  Google Scholar 

  18. Moller C, Dreborg S, Ferdousi HA, et al.: Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT study). J Allergy Clin Immunol 2002, 109:251–256. A study of the very provocative concept that immunotherapy can be used preventively.

    Article  PubMed  Google Scholar 

  19. Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N Engl J Med 2000, 343:1054–1063. A much awaited study, frequently quoted, both for the reassurance that growth velocity was eventually the same for all study groups, as well as for the surprise that budesonide did not alter the remodeling that had already occurred.

    Article  Google Scholar 

  20. Agertoft L, Petersen S: Effect of long-term treatment with inhaled budesonide on adult height in children with asthma. N Engl J Med 2000, 343:1064–1069. A reassuring study, frequently quoted, that children on budesonide achieve their expected adult height.

    Article  Google Scholar 

  21. Goggin N, Macarthus C, Parkin PC: Randomized trial of the addition of ipratropium bromide to albuterol and corticosteroid therapy in children hospitalized because of an acute asthma exacerbation. Arch Pediatr Adolesc Med 2001, 155:1329–1334.

    Article  PubMed  CAS  Google Scholar 

  22. Allergic factors associated with the development of asthma and the influence of cetirizine in a double-blind, randomised, placebo-controlled trial: first results of ETAC. Pediatr Allergy Immunol 1998, 9:116–124.

    Google Scholar 

  23. Spahn JD, Szefler SJ: Childhood asthma: new insights into management. J Allergy Clin Immunol 2002, 109:3–13. A very thorough recent review of the problems in the management of asthma in children.

    Article  PubMed  Google Scholar 

  24. Szefler SJ: Special issues in managing childhood asthma. J Resp D 1998, 19(3A):S35–S41.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Economides, A., White, M.V. (2003). Treatment of Asthma in Children. In: Kaliner, M.A. (eds) Current Review of Asthma. Current Medicine Group, London. https://doi.org/10.1007/978-1-4613-1095-2_12

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-1095-2_12

  • Publisher Name: Current Medicine Group, London

  • Print ISBN: 978-1-4757-0810-3

  • Online ISBN: 978-1-4613-1095-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics