Renal Hemodynamics and Sodium Chloride Excretion

  • Ali A. Khraibi
  • Franklyn G. Knox
Chapter

Abstract

The regulation of renal hemodynamics involves a number of integrated intrinsic and extrinsic control mechanisms. The extrinsic control mechanisms can have an important influence under many physiologic circumstances; however, much attention has been focused on intrinsic controls that are involved in the autoregulation of renal blood flow (RBF) and glomerular filtration rate (GFR).

Keywords

Atrial Natriuretic Peptide Sodium Excretion Atrial Natriuretic Factor Sodium Reabsorption Renal Hemodynamic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Hall, J.E., Guyton, A.C., and Cowley, A.W., Jr., 1977, Dissociation of renal blood flow and filtration rate autoregulation by renin depletion, Am. J. Physiol. 232:F215–F221.PubMedGoogle Scholar
  2. 2.
    Kastner, P.R., Hall, J.E., and Guyton, A.C., 1984, Control of glomerular filtration rate: Role of intrarenally formed angiotensin II, Am. J. Physiol. 246:F897–F906.PubMedGoogle Scholar
  3. 3.
    Textor, S.C., Tarazi, R.C., Novick, A.C., Bravo, E.L., and Fouad, F.M., 1984, Regulation of renal hemodynamics and glomerular filtration in patients with renovascular hypertension during converting enzyme inhibition with captorpil, Am. J. Med. 76:29–37.PubMedGoogle Scholar
  4. 4.
    Hall, J.E., Granger, J.P., and Hester, R.L., 1985, Interaction between adenosine and angiotensin II in controlling glomerular filtration, Am. J. Physiol. 248:F340–F346.PubMedGoogle Scholar
  5. 5.
    Gilmore, J.P., Cornish, K.G., Rogers, S.D., and Joyner, W.L., 1980, Direct evidence for myogenic autoregulation of the renal microcirculation in the hamster, Circ. Res. 47:226–230.PubMedGoogle Scholar
  6. 6.
    Kallskog, U., Lindblom, L.O., Ulfendahl, H.R., and Wolgast, M., 1976, Hydrostatic pressure within the vascular structures of the rat kidney, Pfliigers Arch. 363:205–210.Google Scholar
  7. 7.
    Edwards, R.M., 1983, Segmental effects of norepinephrine and angiotensin II on isolated renal microvessels, Am. J. Physiol. 244:F526–F534.PubMedGoogle Scholar
  8. 8.
    Oien, A.H. and Aukland, K., 1983, A mathematical analysis of the myogenic hypothesis with special reference to autoregulation of renal blood flow, Circ. Res. 52:241–252.PubMedGoogle Scholar
  9. 9.
    Lush, D.J. and Fray, J.C.S., 1984, Steady-state autoregulation of renal blood flow: A myogenic model, Am. J. Physiol. 247:R89–R99.PubMedGoogle Scholar
  10. 10.
    Auckland, K. and Oien, A.H., 1987, Renal autoregulation: Models combining tubuloglomerular feedback and myogenic response, Am. J. Physiol. 252:F768–F783.Google Scholar
  11. 11.
    Moore, L.C., 1984, Tubuloglomerular feedback and SNGFR autoregulation in the rat, Am. J. Physiol. 247:F267–F276.PubMedGoogle Scholar
  12. 12.
    Casellas, D. and Navar, L.G., 1984, In vitro perfusion of juxtamedullary nephrons in rats, Am. J. Physiol. 246:F349–F358.PubMedGoogle Scholar
  13. 13.
    Kreisberg, J.I., Venkatachalam, M., and Troyer, D., 1985, Contractile properties of cultured glomerular mesengial cells, Am. J. Physiol. 249:F457–F463.PubMedGoogle Scholar
  14. 14.
    Young, D.K. and Marsh, D.J., 1981, Pulse wave propagation in rat renal tubules: implications for renal autoregulation, Am. J. Physiol. 240:F466–F458.Google Scholar
  15. 15.
    Sakai, T. and Marsh, D.J., 1983, Analysis of frequency response of renal blood flow autoregulation in rats, Fed. Proc. 42:1090 (Abstract).Google Scholar
  16. 16.
    Sakai, T., Hallman, E., and Marsh, D.J., 1986, Frequency domain analysis of renal autoregulation in the rat, Am. J. Physiol. 250:F364–F373.PubMedGoogle Scholar
  17. 17.
    Wright, F.S. and Briggs, J.P., 1979, Feedback control of glomerular blood flow, pressure, and filtration rate, Physiol. Rev. 59:958–1006.PubMedGoogle Scholar
  18. 18.
    Schnermann, J. and Briggs, J., 1985, Function of the juxtaglomerular apparatus: Local control of glomerular hemodynamics, in: The Kidney: Physiology and Pathophysiology (D.W. Seldin and G. Giebisch, eds.), Raven Press, New York, pp. 669–697.Google Scholar
  19. 19.
    Haberle, D.A. and Von Baeyer, H., 1983, Characteristics of glomerulotubular balance, Am. J. Physiol. 244:F355–F366.PubMedGoogle Scholar
  20. 20.
    Haberle, D.A. and Davis, J.M., 1984, Resetting of tubuloglomerular feedback: Evidence for a humoral factor in tubular fluid, Am. J. Physiol. 246:F495–F500.PubMedGoogle Scholar
  21. 21.
    Briggs, J.P., Steipe, B., Schubert, G., and Schnermann, J., 1982, Micropuncture studies of the renal effects of atrial natriuretic substance, Pflügers Arch. 395:271–276.PubMedGoogle Scholar
  22. 22.
    Schnermann, J., Ploth, D.W., and Hermle, M., 1976, Activation of tubuloglomerular feedback by chloride transport, Pfliigers Arch. 363:229–240.Google Scholar
  23. 23.
    Wright, F.S., 1984, Intrarenal regulation of glomerular filtration rate, J. Hypertension 2:105–113.Google Scholar
  24. 24.
    Bell, P.D. and Navar, L.G., 1982, Relationship between tubuloglomerular feedback responses and perfusate hypotonicity, Kidney Int. 22:234–239.PubMedGoogle Scholar
  25. 25.
    Bell, P.D., 1982, Luminal and cellular mechanisms for the mediation of tubuloglomerular feedback responses, Kidney Int. 22(12)S97–S103.Google Scholar
  26. 26.
    Bell, P.D., McLean, C.B., and Navar, L.G., 1981, Dissociation of tubuloglomerular feedback responses from distal tubular chloride concentration in the rat, Am. J. Physiol. 240:F111–F119.PubMedGoogle Scholar
  27. 27.
    Bell, P.D., 1985, Cyclic AMP-calcium interaction in the transmission of tubuloglomerular feedback signals, Kidney Int. 28:728–732.PubMedGoogle Scholar
  28. 28.
    Bell, P.D., Reddington, M., Ploth, D., and Navar, L.G., 1984, Tubuloglomerular feedbackmediated decreases in glomerular pressure in Munich-Wistar rats, Am. J. Physiol. 247:F877–F880.PubMedGoogle Scholar
  29. 29.
    Tucker, B.J., Steiner, R.W., and Blantz, R.C., 1978, Studies on the tubuloglomerular feedback system in the rat. The mechanism of reduction in filtration rate with benzolamide, J. Clin. Invest. 62:993–1005.PubMedGoogle Scholar
  30. 30.
    Ichikawa, I., 1982, Direct analysis of the effector mechanism of the tubuloglomerular feedback system, Am. J. Physiol. 243:F447–F455.PubMedGoogle Scholar
  31. 31.
    Persson, A.E.G., Gushwa, L.C., and Blantz, R.C., 1984, Feedback pressure-flow responses in normal and angiotensin-prostaglandin-blocked rats, Am. J. Physiol. 247:F925–F931.PubMedGoogle Scholar
  32. 32.
    Seney, F.D., Jr. and Wright, F.S., 1985, Dietary protein suppresses feedback control of glomerular filtration in rats, J. Clin. Invest. 75:558–568.PubMedGoogle Scholar
  33. 33.
    Seney, F.D., Jr., Persson, A.E.G., and Wright, F.S., 1987, Modification of tubuloglomerular feedback signal by dietary protein, Am. J. Physiol. 252:F83–F90.PubMedGoogle Scholar
  34. 34.
    Schnermann, J., Gokel, M., Weber, P.C., Schubert, G., and Briggs, J.P., 1986, Tubuloglomerular feedback and glomerular morphology in Goldblatt hypertensive rats on varying protein diets, Kidney Int. 29:520–529.PubMedGoogle Scholar
  35. 35.
    Bidani, A.K., Schwartz, M.M., and Lewis, E.J., 1987, Renal autoregulation and vulnerability to hypertensive injury in remnant kidney, Am. J. Physiol. 252:F1003–F1010.PubMedGoogle Scholar
  36. 36.
    Moore, L.C. and Mason, J., 1986, Tubuloglomerular feedback control of distal fluid delivery: effect of extracellular volume, Am. J. Physiol. 250:F1024–F1032.PubMedGoogle Scholar
  37. 37.
    Huang, C-L. and Cogan, M.G., 1987, Atrial natriuretic factor inhibits maximal tubuloglomerular feedback response, Am. J. Physiol. 252:F825–F828.PubMedGoogle Scholar
  38. 38.
    Woods, L.L., Mizelle, H.L., and Hall, J.E., 1987, Control of renal hemodynamics in hyperglycemia: possible role of tubuloglomerular feedback, Am. J. Physiol. 252:F65–F73.PubMedGoogle Scholar
  39. 39.
    Boberg, U. and Persson, A.E.G., 1985, Tubuloglomerular feedback during elevated renal venous pressure, Am. J. Physiol. 249:F524–F531.PubMedGoogle Scholar
  40. 40.
    Morsing, P., Stenbergh, A., Müller-Suur, C., and Persson, A.E.G., 1987, Tubuloglomerular feedback in animals with unilateral, partial ureteral occlusion, Kidney Int. 32:212–218.PubMedGoogle Scholar
  41. 41.
    Dilley, J.R. and Arendshorst, W.J., 1984, Enhanced tubuloglomerular feedback activity in rats developing spontaneous hypertension, Am. J. Physiol. 247:F672–F679.PubMedGoogle Scholar
  42. 42.
    Boberg, U. and Persson, A.E.G., 1986, Increased tubuloglomerular feedback activity in Milan hypertensive rats, Am. J. Physiol. 250:F967–F974.PubMedGoogle Scholar
  43. 43.
    Goransson, A. and Sjoquist, M., 1984, The effect of pressor doses of angiotensin II on autoregulation and intrarenal distribution of glomerular filtration rate in the rat, Acta Physiol. Scand. 122: 615–620.PubMedGoogle Scholar
  44. 44.
    Schnermann, J. and Briggs, J., 1986, Role of the renin-angiotensin system in tubuloglomerular feedback, Fed. Proc. 45:1426–1430.PubMedGoogle Scholar
  45. 45.
    Schnermann, J., Briggs, J.P., Schubert, G., and Marin-Grez, M., 1984, Opposing effects of captopril and aprotinin on tubuloglomerular feedback responses, Am. J. Physiol. 247:F912–F918.PubMedGoogle Scholar
  46. 46.
    Boberg, U., Hahne, B., and Persson, A.E.G., 1984, The effect of intraarterial infusion of prostaglandin on the tubuloglomerular feedback control in the rat, Acta Physiol. Scand. 121:65–72.PubMedGoogle Scholar
  47. 47.
    Tanner, G.A., 1985, Tubuloglomerular feedback after nephron or ureteral obstruction, Am. J. Physiol. 248:F688–F697.PubMedGoogle Scholar
  48. 48.
    Wahlberg, J., Stenberg, A., Wilson, D.R., and Persson, A.E.G., 1984, Tubuloglomerular feedback and interstitial pressure in obstructive nephropathy, Kidney Int. 26:294–302.PubMedGoogle Scholar
  49. 49.
    Baylis, C. and Blantz, R.C., 1985, Tubuloglomerular feedback in virgin and 12-day-pregnant rats, Am. J. Physiol. 249:F169–F173.PubMedGoogle Scholar
  50. 50.
    Briggs, J.R., Schubert, G., and Schnermann, A.J., 1984, Quantitative characterization of the tubuloglomerular feedback response: Effect of growth, Am. J. Physiol 247:F808–F815.PubMedGoogle Scholar
  51. 51.
    Sjöquist, M., Göransson, A., and Källskog, Ü., 1984, The influence of tubuloglomerular feedback on the autoregulation of filtration rate in superficial and deep glomeruli, Acta Physiol. Scand. 122: 235–242.PubMedGoogle Scholar
  52. 52.
    Hall, J.E., 1986, Control of sodium excretion by angiotensin II: Intrarenal mechanisms and blood pressure regulation, Am. J. Physiol. 250:R960–R972.PubMedGoogle Scholar
  53. 53.
    Kotchens, T.A., Welch, W.J., Lorenz, J.N., and Ott, C.E., 1987, Renal tubular chloride and renin release, J. Lab. Clin. Med. 110:533–540.Google Scholar
  54. 54.
    Blantz, R.C., 1987, The glomerular and tubular actions of angiotensin II, Am. J. Kidney Dis. 10:2–6.PubMedGoogle Scholar
  55. 55.
    Hall, J.E., Guyton, A.C., Jackson, T.E., Coleman, T.G., Lohmeier, T.E., and Trippodo, N.C., 1977, control of glomerular filtration rate by renin-angiotensin system, Am. J. Physiol. 233:F366–F372.PubMedGoogle Scholar
  56. 56.
    Kastner, P.R., Hall, J.E., and Guyton, A.C., 1982, Renal hemodynamic responses to increased renal venous pressure: role of angiotensin II, Am. J. Physiol. 243:F260–F264.PubMedGoogle Scholar
  57. 57.
    Hall, J.E. and Granger, J.P., 1986, Adenosine alters glomerular filtration control by angiotensin II, Am. J. Physiol. 250:F917–F923.PubMedGoogle Scholar
  58. 58.
    Meyers, B.D., Deen, W.M., and Brenner, B.M., 1975, Effects of norepinephrine and angiotensin II on the determinants of glomerular ultrafiltration and proximal tubule fluid reabsorption in the rat, Circ. Res. 37:101–110.Google Scholar
  59. 59.
    Hall, J.E. and Granger, J.P., 1983, Renal hemodynamic actions of angiotensin II: interaction with tubuloglomerular feedback, Am. J. Physiol. 245:R166–F173.PubMedGoogle Scholar
  60. 60.
    Schnermann, J., Briggs, J.P., and Weber, P.C., 1984, Tubuloglomerular feedback, prostaglandins, and angiotensin in the autoregulation of glomerular filtration rate, Kidney Int. 25:53–64.PubMedGoogle Scholar
  61. 61.
    Navar, L.G. and Rosivall, L., 1984, Contribution of the renin-angiotensin system to the control of intrarenal hemodynamics, Kidney Int. 25:857–868.PubMedGoogle Scholar
  62. 62.
    Navar, L.G., Rosivall, L., Carmines, P.K., and Oparil, S., 1986, Effects of locally formed angiotensin II on renal hemodynamics, Fed. Proc. 45:1448–1453.PubMedGoogle Scholar
  63. 63.
    Mitchell, K.D. and Navar, L.G., 1987, Superficial nephron responses to peritubular capillary infusions of angiotensin I and II, Am. J. Physiol. 252:F818–F824.PubMedGoogle Scholar
  64. 64.
    Wilson, S.K., 1986, The effects of angiotensin II and norepinephrine on afferent arterioles in the rat, Kidney Int. 30:895–905.PubMedGoogle Scholar
  65. 65.
    Steinhausen, M., Kücherer, H., Parekh, N., Weis, S., Wiegman, D.L., and Wilhelm, K., 1986, Angiotensin II control of the renal microcirculation: Effect of blockade by saralasin, Kidney Int. 30:56–61.PubMedGoogle Scholar
  66. 66.
    Faubert, P.F., Chou, S., and Porush, J.G., 1987, Regulation of papillary plasma flow by angiotensin II, Kidney Int. 32:472–478.PubMedGoogle Scholar
  67. 67.
    Chou, S., Faubert, P.F., and Porush, J.G., 1986, Contribution of angiotensin to the control of medullary hemodynamics, Fed. Proc. 45:1438–1443.PubMedGoogle Scholar
  68. 68.
    Mendelsohn, F.A.O., Dunbar, M., Allen, A., Chou, S.T., Millan, M.A., and Aguilera, G., 1986, Angiotensin II receptors in the kidney, Fed. Proc. 45:1420–1425.PubMedGoogle Scholar
  69. 69.
    Inagami, T., Kawamura, M., Naruse, K., and Okamura, T., 1986, Localization of components of the renin-angiotensin system within the kidney, Fed. Proc. 45:1414–1419.PubMedGoogle Scholar
  70. 70.
    Rosivall, L., Narkates, A.J., Oparil, S., and Navar, L.G., 1987, De novo intrarenal formation of angiotensin II during control and enhanced renin secretion, Am. J. Physiol. 252:F1118—F1123.PubMedGoogle Scholar
  71. 71.
    Bellucci, A. and Wilkes, B.M., 1984, Mechanism of sodium modulation of glomerular angiotensin receptors in the rat, J. Clin. Invest. 74:1593–1600.PubMedGoogle Scholar
  72. 72.
    Arend, L.J., Haramati, A., Thompson, C.I., and Spielman, W.S., 1984, Adenosine-induced decreases in renin release: dissociation from hemodynamic effects, Am. J. Physiol. 247:F447–F452.PubMedGoogle Scholar
  73. 73.
    Spielman, W.S., 1984, Antagonistic effect of theophylline on the adenosine-induced decrease in renin release, Am. J. Physiol. 247:F246–F251.PubMedGoogle Scholar
  74. 74.
    Stahl, R.A.K., Paracivini, M., and Schollmeyer, P., 1984, Angiotensin II stimulation of prostaglandin E2 and 6-keto-F1α formation by isolated human glomeruli, Kidney Int. 26:30–34.PubMedGoogle Scholar
  75. 75.
    Cooper, C.L., Schaffer, J.E., and Malik, K.U., 1985, Mechanism of action of angiotensin II and bradykinin on prostaglandin synthesis and vascular tone in the isolated rat kidney, Circ. Res. 56: 97–108.PubMedGoogle Scholar
  76. 76.
    Ardaillou, R., Sraer, J., Chansel, D., Ardaillou, N., and Sraer, J.D., 1987, The effects of angiotensin II on isolated glomeruli and cultured glomerular cells, Kidney Int. 31(20)S74–S80.Google Scholar
  77. 77.
    Dunn, M.J. and Scharschmidt, L.A., 1987, Prostaglandins modulate the glomerular actions of angiotensin II, Kidney Int. 31(20)S95–S101.Google Scholar
  78. 78.
    Katayama, S., Attallah, A.A., Stahl, R.A., and Lee, J.B., 1987, Effect of Sar-l-Ileu-8- angiotensin on renal prostaglandin E2 biosynthesis and excretion, J. Lab. Clin. Med. 109:504–508.PubMedGoogle Scholar
  79. 79.
    Pelayo, J.C., Ziegler, M.G., and Blantz, R.C., 1984, Angiotensin II in adrenergic-induced alteration in glomerular hemodynamics, Am. J. Physiol. 247:F799–F807.PubMedGoogle Scholar
  80. 80.
    Osborn, J.L. and Kinstetter, D.D., 1987, Effects of altered NaCl intake on renal hemodynamic and renin release responses to RNS, Am. J. Physiol. 253:F976–F981.PubMedGoogle Scholar
  81. 81.
    Hayashi, Y., Hisa, H., and Satoh, S., 1987, Role of prostaglandin in norepinephrine and renin release in canine kidney, Am. J. Physiol. 253:F929–F934.PubMedGoogle Scholar
  82. 82.
    Vari, R.C., Freeman, R.H., Davis, J.O., and Sweet, W.D., 1986, Role of renal nerves in rats with low-sodium, one-kidney hypertension, Am. J. Physiol. 250:H189–H194.PubMedGoogle Scholar
  83. 83.
    Mizelle, H.L., Hall, J.E., Woods, L.L., Montani, J., Dzielak, D.J., and Pan, Y., 1987, Role of renal nerves in compensatory adaptation to chronic reductions in sodium intake, Am. J. Physiol. 252:F291–F298.PubMedGoogle Scholar
  84. 84.
    Premen, A.J., Hall, J.E., and Mizelle, H.L., 1985, Maintenance of renal autoregulation during infusion of aminophylline and adenosine, Am. J. Physiol. 248:F366–F373.PubMedGoogle Scholar
  85. 85.
    Deray, G., Branch, R.A., Herzer, W.A., Ohnishi, A., and Jackson, E.K., 1987, Adenosine inhibits p-adrenoceptor but not DBcAMP-induced renin release, Am. J. Physiol. 252:F46–F52.PubMedGoogle Scholar
  86. 86.
    Churchill, P.G. and Bidani, A., 1987, Renal effects of selective adenosine receptor agonists in anesthetized rats, Am. J. Physiol. 252:F299–F303.PubMedGoogle Scholar
  87. 87.
    Pawlowska, D., Granger, J.P., and Knox, F.G., 1987, Effects of adenosine infusion into renal interstitium on renal hemodynamics, Am. J. Physiol. 252:F678–F682.PubMedGoogle Scholar
  88. 88.
    Miyamoto, M., Larson, T.S., Robertson, C.R., and Jamison, R.L., 1987, Effect of intrarenal adenosine on renal function and inner medullary vasa recta blood flow, Clin. Res. 35(5)808A (Abstract).Google Scholar
  89. 89.
    Arend, L.J., Bakris, G.L., Burnett, J.C., Jr., Megerian, C., and Spielman, W.S., 1987, Role of intrarenal adenosine in the renal hemodynamic response to contrast media, J. Lab. Clin. Med. 110: 406–411.PubMedGoogle Scholar
  90. 90.
    Jackson, E.K. and Ohnishi, A., 1987, Development and application of a simple microassay for adenosine in rat plasma, Hypertension 10:189–197.PubMedGoogle Scholar
  91. 91.
    Ruilope, L.M., Robles, R.G., Paya, C., Alcazar, E.M., Sancho-Rof, J., Rodicio, J., Knox, F.G., and Romero, J.C., 1986, Effects of long-term treatment with indomethacin on renal function, Hypertension 8:677–684.PubMedGoogle Scholar
  92. 92.
    Passmore, J.C., Hartupee, D.A., and Jackson, B.A., 1987, Urinary and renal papillary solutes during cyclooxygenase inhibition with ibuprofen, J. Lab. Clin. Med. 110:807–812.PubMedGoogle Scholar
  93. 93.
    Hebert, R.L., Lamoureux, C., Sirois, P., Braquet, P., and Plante, G.E., 1985, Potentiating effects of leukotriene B4 and prostaglandin E2 on urinary sodium excretion by the dog kidney, Prostaglandins Leukotrienes Med., 18:69–80.Google Scholar
  94. 94.
    Kirchner, K.A., Martin, C.J., and Bower, J.D., 1986, Prostaglandin E2 but not I2 restores furosemide response in indomethacin-treated rats, Am. J. Physiol. 250:F980–F985.PubMedGoogle Scholar
  95. 95.
    Patrono, C. and Dunn, M.J., 1987, The clinical significance of inhibition of renal prostaglandin synthesis, Kidney Int. 32:1–12.PubMedGoogle Scholar
  96. 96.
    Carmines, P.K., Bell, P.D., Roman, R.J., Work, J., and Navar, L.G., 1985, Prostaglandins in the sodium excretory response to altered renal arterial pressure in dogs, Am. J. Physiol. 248:F8–F14.PubMedGoogle Scholar
  97. 97.
    Gleim, G.W., Kao-Lo, G., and Maude, D.L., 1984, Pressure natriuresis and prostaglandin secretion by perfused rat kidney, Kidney Int. 26:683–688.PubMedGoogle Scholar
  98. 98.
    Schlondorff, D., Aynedjian, H.S., Satriano, J.A., and Bank, N., 1987, In vivo demonstration of glomerular PGE2 responses to physiological manipulations and experimental agents, Am. J. Physiol. 252:F717–F723.PubMedGoogle Scholar
  99. 99.
    Ruilope, L.M., Rodicio, J., Robles, R.G., Sancho, J., Miranda, B., Granger, J.P., and Romero, J.C., 1987, Influence of a low sodium diet on the renal response to amino acid infusion in humans, Kidney Int. 31:992–999.PubMedGoogle Scholar
  100. 100.
    Benigni, A., Zoja, C., Remuzzi, A., Orisio, S., Piccinelli, A., and Remuzzi, G., 1986, Role of renal prostaglandins in normal and nephrotic rats with diet-induced hyperfiltration, J. Lab. Clin. Med. 108:230–240.PubMedGoogle Scholar
  101. 101.
    Rugiu, C., Oldrizzi, L., and Maschio, G., 1987, Effects of an oral protein load on glomerular filtration rate in patients with solitary kidneys, Kidney Int. 32(22)S29–S31.Google Scholar
  102. 102.
    Dratwa, M., Burette, A., Van Gossum, M., Collart, F., Wens, R., Charlier, L., Tielmans, C., and Deltenre, M., 1987, No rise in glomerular filtration rate after protein loading in cirrhotics, Kidney Int. 32(22)S32–S34.Google Scholar
  103. 103.
    Dhaene, M., Sabot, J., Philippart, Y., Doutrelepont, J., and Vanherweghem, J., 1987, Effects of acute protein loads of different sources on glomerular filtration rate, Kidney Int. 32(22)S25–S28.Google Scholar
  104. 104.
    Viberti, G., Bognetti, E., Wiseman, M.J., Dodds, R., Gross, J.L., and Keen, H., 1987, Effect of protein-restricted diet on renal response to a meat meal in humans, Am. J. Physiol. 253:F388–F393.PubMedGoogle Scholar
  105. 105.
    Woods, L.L., Mizelle, H.L., and Hall, J.E., 1987, Role of the liver in renal hemodynamic response to amino acid infusion, Am. J. Physiol. 252:F981–F985.PubMedGoogle Scholar
  106. 106.
    Castellino, P., Hunt, W., and DeFronzo, R.A., 1987, Regulation of renal hemodynamics by plasma amino acid and hormone concentrations, Kidney Int. 32(22)S15–S20.Google Scholar
  107. 107.
    Castellino, P., Coda, B., and DeFronzo, R.A., 1986, Effect of amino acid infusion on renal hemodynamics in humans, Am. J. Physiol. 251:F132–F140.PubMedGoogle Scholar
  108. 108.
    Manning, R.D., Jr., 1987, Effects of hypoproteinemia on renal hemodynamics, arterial pressure, and fluid volume, Am. J. Physiol. 252:F91–F98.PubMedGoogle Scholar
  109. 109.
    Manning, R.D., Jr., 1987, Renal hemodynamics, fluid volume, and arterial pressure changes during hyperproteinemia, Am. J. Physiol. 252:F403–F411.PubMedGoogle Scholar
  110. 110.
    Baines, A.D., Drangova, R., and Ho, P., 1987, α1Adrenergic stimulation of renal Na reabsorption requires glucose metabolism, Am. J. Physiol. 253:F810–F815.PubMedGoogle Scholar
  111. 111.
    Premen, A.J., 1987, Splanchnic and renal hemodynamic responses to intraportal infusion of glucagon, Am. J. Physiol. 253:F1105–F1112.PubMedGoogle Scholar
  112. 112.
    Hirschberg, R. and Kopple, J.D., 1987, Effect of growth hormone on GFR and renal plasma flow in man, Kidney Int. 32(22)S21–S24.Google Scholar
  113. 113.
    Corman, B. and Michel, J-B., 1987, Glomerular filtration, renal blood flow, and solute excretion in conscious aging rats, Am. J. Physiol. 253:R555–R560.PubMedGoogle Scholar
  114. 114.
    Baylis, C., 1987, The determinants of renal hemodynamics in pregnancy, Am. J. Kidney Dis. 9: 260–264.PubMedGoogle Scholar
  115. 115.
    Barron, W.M., 1987, Volume homeostasis during pregnancy in the rat, Am. J. Kidney Dis. 9: 296–302.PubMedGoogle Scholar
  116. 116.
    Yarger, W.E., Newman, W.J., and Klotman, P.E., 1987, Renal effects of aprotinin after 24 hours of unilateral ureteral obstruction, Am. J. Physiol. 253:F1006–F1014.PubMedGoogle Scholar
  117. 117.
    Badr, K.F., Brenner, B.M., and Ichikawa, I., 1987, Effects of leukotriene D4 on glomerular dynamics in the rat, Am. J. Physiol. 253:F239–F243, 1987.PubMedGoogle Scholar
  118. 118.
    Bourgoignie, J.J., Gavellas, G., Martinez, E., and Pardo, V., 1987, Glomerular function and morphology after renal mass reduction in dogs, J. Lab. Clin. Med. 109:380–388.PubMedGoogle Scholar
  119. 119.
    Iversen, B.M., Sekse, I., and Ofstad, J., 1987, Resetting of renal blood flow autoregulation in spontaneously hypertensive rats, Am. J. Physiol. 252:F480–F486.PubMedGoogle Scholar
  120. 120.
    Roos, J.C., Koomans, H.A., Dorhout Mees, E.J., and Delawi, I.M.K., 1985, Renal sodium handling in normal humans subjected to low, normal, and extremely high sodium supplies, Am. J. Physiol. 249:F941–F947.PubMedGoogle Scholar
  121. 121.
    Brensilver, J.M., Daniels, F.H., Lafavour, G.S., Malseptic, R.M., Lorch, J.A., Ponte, M.L., and Cortell, S., 1985, Effect of variations in dietary sodium intake on sodium excretion in mature rats, Kidney Int. 27:497–502.PubMedGoogle Scholar
  122. 122.
    Navar, L.G., Paul, R.V., Carmines, P.K., Chou, C., and Marsh, D.J., 1986, Intrarenal mechanisms mediating pressure natriuresis: role of angiotensin and prostaglandins, Fed. Proc. 45: 2885–2891.PubMedGoogle Scholar
  123. 123.
    Roman, R.J., 1986, Pressure diuresis mechanism in the control of renal function and arterial pressure, Fed. Proc. 45:2878–2884.PubMedGoogle Scholar
  124. 124.
    Haas, J.A., Granger, J.P., and Knox, F.G., 1986, Effect of renal perfusion pressure on sodium reabsorption from proximal tubules of superficial and deep nephrons, Am. J. Physiol. 250:F425–F429.PubMedGoogle Scholar
  125. 125.
    Knox, F.G. and Granger, J.P., 1987, control of sodium excretion: the kidney produces under pressure, NIPS 2:26–29.Google Scholar
  126. 126.
    Harris, P.J. and Navar, L.G., 1985, Tubular transport responses to angiotensin, Am. J. Physiol. 248:F621–F630.PubMedGoogle Scholar
  127. 127.
    Schuster, V.L., 1986, Effects of angiotensin on proximal tubular reabsorption, Fed. Proc. 45: 1444–1447.PubMedGoogle Scholar
  128. 128.
    Hall, J.E., 1986, Regulation of glomerular filtration rate and sodium excretion by angiotensin II, Fed. Proc. 45:1431–1437.PubMedGoogle Scholar
  129. 129.
    Navar, L.G., Carmines, P.K., Huang, W., and Mitchell, K.D., 1987, The tubular effects of angiotensin II, Kidney Int. 31(20)S81–S88.Google Scholar
  130. 130.
    Olsen, M.E., Hall, J.E., Montani, J., Guyton, A.C., Langford, H.G., and Cornell, J.E., 1985, Mechanisms of angiotensin II natriuresis and antinatriuresis, Am. J. Physiol. 249:F299–F307.PubMedGoogle Scholar
  131. 131.
    Hall, J.E., Coleman, T.G., Guyton, A.C., Balfe, J.W., and Salgado, H.C., 1979, Intrarenal role of angiotensin II and [des-Asp1] angiotensin II, Am. J. Physiol. 236:F252–F259.PubMedGoogle Scholar
  132. 132.
    Schuster, V.L., Kokko, J.P., and Jacobson, H.R., 1984, Angiotensin II directly stimulates sodium transport in rabbit proximal convoluted tubules, J. Clin. Invest. 73:507–515.PubMedGoogle Scholar
  133. 133.
    Stokes, J.B., 1981, Prostaglandins and the regulation of NaCl transport across renal epithelia, Mineral Electrolyte Metab. 6:35–45.Google Scholar
  134. 134.
    deBold, A.J., Borenstein, H.B., Veress, A.T., and Sonnenberg, H., 1981, A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats, Life Sci. 28: 89–95.Google Scholar
  135. 135.
    Frolich, E.D., 1986, “Introduction,” First Intl. Symp. and Swiss Hypertension Workshop on Atrial Natriuretic Peptides, 18-19 November, 1985, Berne, Switzerland, O. Weidman, E.D. Frolich and J.H. Laragh, eds., Gower Publ. Co., London, J. Hypertension. 4(2):S1-S2.Google Scholar
  136. 136.
    Knorr, M., Locher, R., Stimpel, M., Edmonds, D., and Vetter, W., 1986, Effect of atrial natriuretic polypeptide on angiotensin II-induced increase of cytosolic free calcium in cultured smooth muscle cells, J. Hypertension 4(2)S67–S69.Google Scholar
  137. 137.
    Schiffrin, E.L., St-Louis, J., Garcia, R., Thibault, G., Cantin, M., and Genest, J., 1986, Vascular and adrenal binding sites for atrial natriuretic factor. Effects of sodium and hypertension, Hypertension 8(I)I141–I145.Google Scholar
  138. 138.
    deBold, A.J., deBold, M.L., and Sarda, I.R., 1986, Functional-morphological studies on in vitro cardionatrin release, J. Hypertension 4(2)S3–S7.Google Scholar
  139. 139.
    Goetz, K.L., 1986, Atrial receptors, natriuretic peptides, and the kidney: Current understanding, Mayo Clin. Proc. 61:600–603.PubMedGoogle Scholar
  140. 140.
    Trippodo, N.C., Cole, F.E., MacPhee, A.A., and Pegram, B.L., 1987, Biological mechanisms of atrial natriuretic factor, J. Lab. Clin. Med. 109:112–119.PubMedGoogle Scholar
  141. 141.
    Cantin, M. and Genest, J., 1987, The heart as an endocrine gland, Hypertension 10(I)1118–1121.Google Scholar
  142. 142.
    Cole, B.R., Schwartz, D., Manning, P.T., Katsube, N.C., and Needleman, P., 1986, Atriopeptins: Circulating volume regulatory hormones with potential therapeutic role in chronic renal failure, J. Hypertension 4(2)S13–S16.Google Scholar
  143. 143.
    Inagami, T., Misono, K.S., Fukumi, H., Maki, M., Tanaka, I., Takayanagi, R., Imada, T., Grammer, R.T., Naruse, M., Naruse, K., Pandey, K.N., Parmentier, M., Yasujima, M., and Abe, K., 1987, Structure and physiological actions of rat atrial natriuretic factor, Hypertension 10 (I)1113–1117.Google Scholar
  144. 144.
    Thibault, G., Garcia, R., and Gutkowska, J., 1986, Identification of the released form of atrial natriuretic factor by the perfused rat heart, Proc. Soc. Exp. Biol. Med. 182:137–141.PubMedGoogle Scholar
  145. 145.
    Miyata, A., Kangawa, K., and Matsuo, H., 1986, Molecular forms of atrial natriuretic peptides in rat tissues and plasma, J. Hypertension 4(2)S9–S11.Google Scholar
  146. 146.
    Fried, T.A., Ayon, M.A., McDonald, G., Lau, A., Inagami, T., and Stein, J.H., 1987, Atrial natriuretic peptide, right atrial pressure, and sodium excretion rate in the rat, Am. J. Physiol. 253: F969–F975.PubMedGoogle Scholar
  147. 147.
    Schiebinger, R.J. and Linden, J., 1986, The influence of resting tension on immunoreactive atrial natriuretic peptide secretion by rat atria supervised in vitro, Circ. Res. 59:105–109.PubMedGoogle Scholar
  148. 148.
    Bilder, G.E., Schofield, T.L., and Blaine, E.H., 1986, Release of atrial natriuretic factor. Effects of repetitive stretch and temperature, Am. J. Physiol. 251:F817–F821.PubMedGoogle Scholar
  149. 149.
    Kohno, M., Clegg, K.B., and Sambhi, M.P., 1987, Effects of volume change on circulating immunoreactive atrial natriuretic factor in rats, Hypertension 10:171–175.PubMedGoogle Scholar
  150. 150.
    Eskay, R., Zukowska-Grojec, Z., Haass, M., Dave, J.R., and Zamir, N., 1986, Circulating atrial natriuretic peptides in conscious rats: Regulation of release by multiple factors, Science 232:636–639.PubMedGoogle Scholar
  151. 151.
    Verburg, K.M., Freeman, R.H., Davis, J.O., Villarreal, D., and Vari, R.C., 1986, Control of atrial natriuretic factor release in conscious dogs, Am. J. Physiol. 251:R947–R956.PubMedGoogle Scholar
  152. 152.
    Wei, Y., Rodi, C.P., Day, M.L., Wiegand, R.C., Needleman, L.D., Cole, B.R., and Needleman, P., 1987, Developmental changes in the rat atriopeptin hormonal system, J. Clin. Invest. 79:1325–1329.PubMedGoogle Scholar
  153. 153.
    Raine, A.E.G., Erne, P., Burgisser, E., Müller, F.B., Bolli, P., Burkart, F., and Bühler, F.R., 1986, Atrial natriuretic peptide and atrial pressure in patients with congestive heart failure, N. Engl. J. Med. 315:533–537.PubMedGoogle Scholar
  154. 154.
    Müller, F.B., Erne, P., Raine, A.E.G., Bolli, P., Linder, L., Resink, T.J., Cottier, C., and Buhler, F.R., 1986, Atrial antipressor natriuretic peptide: release mechanisms and vascular action in man, J. Hypertension 4(2)S109–S114.Google Scholar
  155. 155.
    Anderson, J.V., Gibbs, J.S.R., Woodruff, P.W.R., Greco, C., Rowland, E., and Bloom, S.R., 1986, The plasma atrial natriuretic peptide response to treatment of acute cardiac failure, spontaneous supraventricular tachycardia and induced re-entrant tachycardia in man, J. Hypertension 4(2)S137–S141.Google Scholar
  156. 156.
    Miki, K., Hajduczok, G., Klocke, M.R., Krasney, J.A., Hong, S.K., and deBold, A.J., 1986, Atrial natriuretic factor and renal function during head-out water immersion in conscious dogs, Am. J. Physiol. 251:R1000–R1008.PubMedGoogle Scholar
  157. 157.
    Nishida, Y., Miyata, A., Morita, H., Uemura, N., Kangawa, K., Matsuo, H., and Hosomi, H., 1987, Lack of neural control of atrial natriuretic peptide release in conscious dogs, Am. J. Physiol. 253:F1164–F1170.PubMedGoogle Scholar
  158. 158.
    Goetz, K.L., Wang, B.C., Geer, P.G., Leadley, R.J., Jr., and Reinhardt, H.W., 1986, Atrial stretch increases sodium excretion independently of release of atrial peptides, Am. J. Physiol. 250: R946–R950.PubMedGoogle Scholar
  159. 159.
    Lang, R.E., Dietz, R., Merkel, A., Unger, T., Ruskoaho, H., and Ganten, D., 1986, Plasma atrial natriuretic peptide values in cardiac diseases, J. Hypertension 4(2)S119–S123.Google Scholar
  160. 160.
    Burnett, J.C., Jr., Kao, P.C., Hu, D.C., Heser, D.W., Heublein, D., Granger, J.P., Opgenorth, T.J., and Reeder, G.S., 1986, Atrial natriuretic peptide elevation in congestive heart failure in the human, Science 231:1145–1147.PubMedGoogle Scholar
  161. 161.
    Espiner, E.A., Nicholls, M.G., Yandle, T.G., Crozier, I.G., Cuneo, R.C., McCormick, D., and Ikram, H., 1986, Studies on the secretion, metabolism and action of atrial natriuretic peptide in man, J. Hypertension 4(2)S85–S91.Google Scholar
  162. 162.
    Mendez, R.E., Pfeffer, J.M., Ortola, F.V., Bloch, K.D., Anderson, S., Seidman, J.G., and Brenner, B.M., 1987, Atrial natriuretic peptide transcription, storage, and release in rats with myocardial infarction, Am. J. Physiol. 253:H1449–H1455.PubMedGoogle Scholar
  163. 163.
    . Tsunoda, K., Hodsman, G.P., Sumithran, E., and Johnston, C.I., 1986, Atrial natriuretic peptide in chronic heart failure in the rat: A correlation with ventricular dysfunction, Circ. Res. 59:256–261.PubMedGoogle Scholar
  164. 164.
    Edwards, B.S., Ackermann, D.M., Schwab, T.R., Heublein, D.M., Edwards, W.D., Wold, L.E., and Burnett, J.C., Jr., 1986, The relationship between atrial granularity and circulating atrial natriuretic peptide in hamsters with congestive heart failure, Mayo Clin. Proc. 61:517–521.PubMedGoogle Scholar
  165. 165.
    Montorsi, P., Tonolo, G., Polonia, J., Hepburn, D., and Richards, A.M., 1987, Correlates of plasma atrial natriuretic factor in health and hypertension, Hypertension 10:570–576.PubMedGoogle Scholar
  166. 166.
    Arendt, R.M., Gerbes, A.L., Riter, D., Stangl, E., Bach, P., and Zähringer, J., 1986, Atrial natriuretic factor in plasma of patients with arterial hypertension, heart failure or cirrhosis of the liver, J. Hypertension 4(2)S131–S135.Google Scholar
  167. 167.
    Onwochei, M.O., Snajdar, R.M., and Rapp, J.P., 1987, Release of atrial natriuretic factor from heart-lung preparations of inbred Dahl rats, Am. J. Physiol. 253:H1044–H1052.PubMedGoogle Scholar
  168. 168.
    Lattion, A.-L., Michel, J.-B., Arnauld, E., Corvol, P., and Soubrier, F., 1986, Myocardial recruitment during ANF mRNA increase with volume overload in the rat, Am. J. Physiol. 251: H890–H896.PubMedGoogle Scholar
  169. 169.
    Walsh, K.P., Williams, T.D.M., Canepa-Anson, R., Pitts, E., Lightman, S.L., and Sutton, R., 1987, Effects of endogenous atrial natriuretic peptide released by rapid atrial pacing in dogs, Am. J. Physiol. 253:R599–R604.PubMedGoogle Scholar
  170. 170.
    Freeman, R.H., Villarreal, D., Vari, R.C., and Verburg, K.M., 1987, Endogenous atrial natriuretic factor in dogs with caval constriction, Circ. Res. 61(I)I96–199.PubMedGoogle Scholar
  171. 171.
    Suzuki, M., Almeida, F.A., Nussenzveig, D.R., Sawyer, D., and Maack, T., 1987, Binding and functional effects of atrial natriuretic factor in isolated rat kidney, Am. J. Physiol. 253:F917–F928.PubMedGoogle Scholar
  172. 172.
    Weidmann, P., Hasler, L., Gnädinger, M.P., Lang, R.E., Uehlinger, D.E., Shaw, S., Rascher, W., and Reubi, F.C., 1986, Blood levels and renal effects of atrial natriuretic peptide in normal man, J. Clin. Invest. 77:734–742.PubMedGoogle Scholar
  173. 173.
    Biollaz, J., Nussberger, J., Waeber, B., and Brunner, H.R., 1986, Clinical pharmacology of atrial natriuretic (3-28) eicosahexapeptide, J. Hypertension 4(2)S101–S108.Google Scholar
  174. 174.
    Trippodo, N.C., Kardon, M.B., Pegram, B.L., Cole, F.E., and MacPhee, A.A., 1986, Acute haemodynamic effects of the atrial natriuretic hormone in rats, J. Hypertension 4(2)S35–S40.Google Scholar
  175. 175.
    Garcia, R., Cantin, M., Cusson, J.R., Genest, J., Gutkowska, J., Larochelle, P., Schiffrin, E.L., and Thibault, G., 1986, Some physiopathological aspects of atrial natriuretic factor, J. Hypertension 4(2)S125–S129.Google Scholar
  176. 176.
    Natsume, T., Kardon, M.B., Trippodo, N.C., Januszewicz, A., Pegram, B.L., and Frolich, E.D., 1986, Atriopeptin III does not alter cardiac performance in rats, J. Hypertension 4:477–480.Google Scholar
  177. 177.
    Gaillard, C.A., Koomans, H.A., Rabelink, A.J., and Dorhout Mees, E.J., 1987, Effects of indomethacin on renal response to atrial natriuretic peptide, Am. J. Physiol. 253:F868–F873.PubMedGoogle Scholar
  178. 178.
    Krayacich, J., Kline, R.L., Macchi, A., and Calaresu, F.R., 1986, Renal responses to atriopeptin II are not dependent on renal nerves, Am. J. Physiol. 251:R187–R191.PubMedGoogle Scholar
  179. 179.
    Seymour, A.A., Smith, S.G., III, and Mazack, E.K., 1987, Effects of renal perfusion pressure on the natriuresis induced by atrial natriuretic factor, Am. J. Physiol. 253:F234–F238.PubMedGoogle Scholar
  180. 180.
    Blaine, E.H., Heinel, L.A., Schorn, T.W., Marsh, E.A., and Whinnery, M.A., 1986, The character of the atrial natriuretic response: pressure and volume effects, J. Hypertension 4(2)S17–S24.Google Scholar
  181. 181.
    Davis, C.L. and Briggs, J.P., 1987, Effect of reduction in renal artery pressure on atrial natriuretic peptide-induced natriuresis, Am. J. Physiol. 252:F146–F153.PubMedGoogle Scholar
  182. 182.
    Mendez, R.E., Dunn, B.R., Troy, J.L., and Brenner, B.M., 1986, Modulation of the natriuretic response to atrial natriuretic peptide by alterations in peritubular Starling forces in the rat, Circ. Res. 59:605–611.PubMedGoogle Scholar
  183. 183.
    Opgenorth, T.J., Burnett, J.C., Jr., Granger, J.P., and Scriven, T.A., 1986, Effects of atrial natriuretic peptide on renin secretion in nonfiltering kidney, Am. J. Physiol. 250:F798–F801.PubMedGoogle Scholar
  184. 184.
    Itoh, S., Abe, K., Nushiro, N., Omata, K., Yasujima, M., and Yoshinaga, K., 1987, Effect of atrial natriuretic factor on renin release in isolated afferent arterioles, Kidney Int. 32:493–497.PubMedGoogle Scholar
  185. 185.
    Deray, G., Branch, R.A., Herzer, W.A., Ohnishi, A., and Jackson, E.K., 1987, Effects of atrial natriuretic factor on hormone-induced renin release, Hypertension 9:513–517.PubMedGoogle Scholar
  186. 186.
    Holtz, J., Sommer, O., and Bassenge, E., 1987, Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs, Hypertension 9:350–354.PubMedGoogle Scholar
  187. 187.
    Kiberd, B.A., Larson, T.S., Robertson, C.R., and Jamison, R.L., 1987, Effect of atrial natriuretic peptide on vasa recta blood flow in the rat, Am. J. Physiol. 252:F1112—F1117.PubMedGoogle Scholar
  188. 188.
    Takezawa, K., Cowley, A.W., Jr., Skelton, M., and Roman, R.J., 1987, Atriopeptin III alters renal medullary hemodynamics and the pressure-diuresis response in rats, Am. J. Physiol. 252: F992–F1002.PubMedGoogle Scholar
  189. 189.
    Hildebrandt, D.A. and Banks, R.O., 1987, Effect of atrial natriuretic factor on renal function in rats with papillary necrosis, Am. J. Physiol. 252:F977–F980.PubMedGoogle Scholar
  190. 190.
    Davis, C.L. and Briggs, J.P., 1987, Effect of atrial natriuretic peptides on renal medullary solute gradients, Am. J. Physiol. 253:F679–F684.PubMedGoogle Scholar
  191. 191.
    Cogan, M.G., 1986, Atrial natriuretic factor can increase renal solute excretion primarily by raising glomerular filtration, Am. J. Physiol. 250:F710–F714.PubMedGoogle Scholar
  192. 192.
    Dunn, B.R., Ichikawa, I., Pfeffer, J.M., Troy, J.L., and Brenner, B.M., 1986, Renal and systemic hemodynamic effects of synthetic atrial natriuretic peptide in the anesthetized rat, Circ. Res. 59:237–246.PubMedGoogle Scholar
  193. 193.
    Fried, T.A., McCoy, R.N., Osgood, R.W., and Stein, J.H., 1986, Effect of atriopeptin II on determinants of glomerular filtration rate in the in vitro perfused dog glomerulus, Am. J. Physiol. 250:F1119–F1122.PubMedGoogle Scholar
  194. 194.
    Shimonaka, M., Saheki, T., Hagiwara, H., Hagiwara, Y., Sono, H., and Hirose, S., 1987, Visualization of ANP receptor on glomeruli of bovine kidney by use of a specific antiserum, Am. J. Physiol. 253:F1058–F1062.PubMedGoogle Scholar
  195. 195.
    Burnett, J.C., Jr., Opgenorth, T.J., and Granger, J.P., 1986, The renal action of atrial natriuretic peptide during control of glomerular filtration, Kidney Int. 30:16–19.PubMedGoogle Scholar
  196. 196.
    Pollock, D.M. and Arendshorst, W.J., 1986, Effect of atrial natriuretic factor on renal hemodynamics in the rat, Am. J. Physiol. 251:F795–F801.PubMedGoogle Scholar
  197. 197.
    Salazar, F.J., Granger, J.P., Fiksen-Olsen, M.J., Bentley, M.D., and Romero, J.C., 1987, Possible modulatory role of angiotensin II on atrial peptide-induced natriuresis, Am. J. Physiol. 253:F880–F883.PubMedGoogle Scholar
  198. 198.
    Paul, R.V., Kirk, K.A., and Navar, L.G., 1987, Renal autoregulation and pressure natriuresis during ANF-induced diuresis, Am. J. Physiol. 253:F424–F431.PubMedGoogle Scholar
  199. 199.
    Roy, D.R., 1986, Effect of synthetic ANP on renal and loop of Henle functions in the young rat, Am. J. Physiol. 251:F220–F225.PubMedGoogle Scholar
  200. 200.
    Bourgoignie, J.J., Gavellas, G., and Hwang, K.H., 1986, Renal effects of atrial natriuretic factor in primate, Am. J. Physiol. 251 :F1049–F1054.PubMedGoogle Scholar
  201. 201.
    Biollaz, J., Bidiville, J., Diezi, J., Waeber, B., Nussberger, J., Brunner-Ferber, F., Gomez, H.J., and Brunner, H.R., 1987, Site of the action of a synthetic atrial natriuretic peptide evaluated in humans, Kidney Int. 32:537–546.PubMedGoogle Scholar
  202. 202.
    Burnett, J.C., Jr., Granger, J.P., and Opgenorth, T.J., 1984, Effects of synthetic atrial natriuretic factor on renal function and renin release, Am. J. Physiol. 247:F863–F866.PubMedGoogle Scholar
  203. 203.
    Hammond, T.G., Yusufi, A.N.K., Knox, F.G., and Dousa, T.P., 1985, Administration of atrial natriuretic factor inhibits sodium-coupled transport in proximal tubules, J. Clin. Invest. 75: 1983–1989.PubMedGoogle Scholar
  204. 204.
    Baum, M. and Toto, R.D., 1986, Lack of a direct effect of atrial natriuretic factor in the rabbit proximal tubule, Am. J. Physiol. 250:F66–F69.PubMedGoogle Scholar
  205. 205.
    Spinelli, F., Kamber, B., and Schnell, C., 1986, Observations on the natriuretic response to intravenous infusions of atrial natriuretic factor in water-loaded anesthetized rats, J. Hypertension 4(2)S25–S29.Google Scholar
  206. 206.
    Harris, P.J., Thomas, D., and Morgan, T.O., 1987, Atrial natriuretic peptide inhibits angiotensin- stimulated proximal tubular sodium and water reabsorption, Nature 326:697–698.PubMedGoogle Scholar
  207. 207.
    Peterson, L.N., De Rouffignac, C., Sonnenberg, H., and Levine, D.Z., 1987, Thick ascending limb response to dDAVP and atrial natriuretic factor in vivo, Am. J. Physiol. 252:F374–F381.PubMedGoogle Scholar
  208. 208.
    Sonnenberg, H., Honrath, U., Chong, C.K., and Wilson, D.R., 1986, Atrial natriuretic factor inhibits sodium transport in medullary collecting duct, Am. J. Physiol. 250:F963–F966.PubMedGoogle Scholar
  209. 209.
    Cantiello, H.F. and Ausiello, D.A., 1986, atrial natriuretic factor and cGMP inhibit amiloridesensitive Na+ transport in the cultured renal epithelial cell line, LLC-PK1, Biochem. Biophys. Res. Commun. 134:852–860.PubMedGoogle Scholar
  210. 210.
    Hamet, P., Tremblay, J., Pang, S.C., Skuherska, R., Schiffrin, E.L., Garcia, R., Cantin, M., Genest, J., Palmour, R., Ervin, F.R., Martin, S., and Goldwater, R., 1986, Cyclic GMP as mediator and biological marker of atrial natriuretic factor, J. Hypertension 4(2)S49–S56.Google Scholar
  211. 211.
    Ballerman, B.J. and Brenner, B.M., 1986, Role of atrial peptides in body fluid homeostasis, Circ. Res. 58:619–630.Google Scholar
  212. 212.
    Huang, C-L., Ives, H.E., and Cogan, M.G., 1986, In vivo evidence that cGMP is the second messenger for atrial natriuretic factor, Proc. Natl. Acad. Sci. USA 83:8015–8018.PubMedGoogle Scholar
  213. 213.
    Zeidel, M.L. and Brenner, B.M., 1987, Actions of atrial natriuretic peptides on the kidney, Semin. Nephrol. 7:91–97.PubMedGoogle Scholar
  214. 214.
    Edwards, R.M. and Weidley, E.F., 1987, Lack of effect of atriopeptin II on rabbit glomerular arterioles in vitro, Am. J. Physiol. 252:F317–F321.PubMedGoogle Scholar
  215. 215.
    Appel, R.G. and Dunn, M.J., 1987, Papillary collecting tubule responsiveness to atrial natriuretic factor in Dahl rats, Hypertension 10:107–114.PubMedGoogle Scholar
  216. 216.
    Zeidel, M.L., Silva, P., Brenner, B.M., and Seifter, J.L., 1987, cGMP mediates effects of atrial peptides on medullary collecting duct cells, Am. J. Physiol. 252:F551–F559.PubMedGoogle Scholar
  217. 217.
    Schriven, T.A., and Burnett, J.C., Jr., 1985, Effects of synthetic atrial natriuretic peptide on renal function and renin release in acute experimental heart failure, Circulation 72:892–897.Google Scholar
  218. 218.
    Laragh, J.H., 1985, Atrial natriuretic hormone, the renin-aldosterone axis, and blood pressureelectrolyte homeostasis, N. Engl. J. Med. 313:1330–1340.PubMedGoogle Scholar
  219. 219.
    Vari, R.C., Freeman, R.H., Davis, J.O., Villarreal, D., and Verburg, K.M., 1986, Effect of synthetic atrial natriuretic factor on aldosterone secretion in the rat, Am. J. Physiol. 251:R48–R52.PubMedGoogle Scholar
  220. 220.
    Goodfriend, T.L., Elliott, M.E., and Atlas, S.A., 1984, Actions of synthetic atrial natriuretic factor on bovine adrenal glomerulosa, Life Sci. 35:1675–1682.PubMedGoogle Scholar
  221. 221.
    Chartier, L., Schiffrin, E., and Thibault, G., 1984, Effect of atrial natriuretic factor (ANF)-related peptides on aldosterone secretion by adrenal glomerulosa cells: Critical role of the intramolecular disulphide bond, Biochem. Biophys. Res. Commun. 122:171–174.PubMedGoogle Scholar
  222. 222.
    Campbell, W.B., Currie, M.G., and Needleman, P., 1985, Inhibition of aldosterone biosynthesis by atriopeptins in rat adrenal cells, Circ. Res. 57:113–118.PubMedGoogle Scholar
  223. 223.
    Chartier, L., Schiffrin, E., Thibault, G., and Garcia, R., 1984, Atrial natriuretic factor inhibits the stimulation of aldosterone secretion by angiotensin II, ACTH, and potassium in vitro and angiotensin II-induced steroidogenesis in vivo, Endocrinology 115:2026–2028.PubMedGoogle Scholar
  224. 224.
    Sagnella, G.A., Markandu, N.D., Shore, A.C., and MacGregor, G.A., 1986, Changes in plasma immunoreactive atrial natriuretic peptide in response to saline infusion or to alterations in dietary sodium intake in normal subjects, J. Hypertension 4(2)S115–SI18.Google Scholar
  225. 225.
    Salazar, F.J., Granger, J.P., Joyce, M.L.M., Burnett, J.C., Jr., Bove, A.A., and Romero, J.C., 1986, Effects of hypertonic saline infusion and water drinking on atrial peptide, Am. J. Physiol. 251:R1091-R1094.Google Scholar
  226. 226.
    Epstein, M., Loutzenhiser, R.D., Friedland, E., Aceto, R.M., Camargo, M.J.F., and Atlas, S.A., 1986, Increases in circulating atrial natriuretic factor during immersion-induced central hypervolaemia in normal humans, J. Hypertension 4(2)S93–S99.Google Scholar
  227. 227.
    Schwab, T.R., Edwards, B.S., Heublein, D.M., and Burnett, J.C., Jr., 1986, Role of atrial natriuretic peptide in volume-expansion natriuresis, Am. J. Physiol. 251:R310–R313.PubMedGoogle Scholar
  228. 228.
    Villarreal, D., Freeman, R.H., Davis, J.O., Verburg, K.M., and Vari, R.C., 1986, Effects of atrial appendectomy on circulating atrial natriuretic factor during volume expansion in the rat, Proc. Soc. Exp. Biol. Med. 183:54–58.PubMedGoogle Scholar
  229. 229.
    Hirth, C., Stasch, J-P., John, A., Kazda, S., Morich, F., Neuser, D., and Wohlfeil, S., 1986, The renal response to acute hypervolemia is caused by atrial natriuretic peptides, J. Cardiovasc. Pharm. 8:268–275.Google Scholar
  230. 230.
    Benjamin, B.A., Metzler, C.H., and Peterson, T.V., 1987, Renal response to volume expansion in atrial-appendectomized dogs, Am. J. Physiol. 253:R786–R793.PubMedGoogle Scholar
  231. 231.
    Trippoda, N.C., 1987, An update on the physiology of atrial natriuretic factor, Hypertension 10 (1)1122–1127.Google Scholar
  232. 232.
    Khraibi, A.A., Granger, J.P., Burnett, J.C., Jr., Walker, K.R., and Knox, F.G., 1987, Role of atrial natriuretic factor in the natriuresis of acute volume expansion, Am. J. Physiol. 252:R921–R924.PubMedGoogle Scholar
  233. 233.
    Barbee, R.W. and Trippodo, N.C., 1987, The contribution of atrial natriuretic factor to acute volume natriuresis in rats, Am. J. Physiol. 253:F1129–F1135.PubMedGoogle Scholar
  234. 234.
    Kaneko, K., Okada, K., Ishikawa, S-E., Kuzuya, T., and Saito, T., 1987, Role of atrial natriuretic peptide in natriuresis in volume-expanded rats, Am. J. Physiol. 253:R877–R882.PubMedGoogle Scholar
  235. 235.
    Hofbauer, K.G., Criscione, L., Sonnenburg, C., Muir, A., and Mah, S.C., 1986, Acute and chronic haemodynamic and natriuretic effects of atriopeptin II in conscious rats, J. Hypertension 4 (2)S41–S47.Google Scholar
  236. 236.
    Laragh, J.H., 1986, The endocrine control of blood volume, blood pressure and sodium balance: Atrial hormone and renin system interactions, J. Hypertension 4(2)S143–S156.Google Scholar
  237. 237.
    Sugawara, A., Nakao, K., Morii, N., Sakamoto, M., Horii, K., Shimokura, M., Kiso, Y., Nishimura, K., Ban, T., Kihara, M., Yamori, Y., Kangawa, K., Matsuo, H., and Imura, H., 1986, Significance of α-human atrial natriuretic polypeptide as a hormone in humans, Hypertension 8(I)1151–1155.Google Scholar
  238. 238.
    Ballerman, B.J. and Brenner, B.M., 1987, Atrial natriuretic peptide and the kidney, Am. J. Kidney Dis. X(l)7–12.Google Scholar
  239. 239.
    Casto, R., Hilbig, J., Schroeder, G., and Stock, G., 1987, Atrial natriuretic factor inhibits central angiotension II pressor responses, Hypertension 9:473–477.PubMedGoogle Scholar
  240. 240.
    Maddox, D.A. and Gennari, J.F., 1987, The early proximal tubule: A high-capacity deliveryresponsive reabsorptive site, Am. J. Physiol. 252:F573–F584.PubMedGoogle Scholar
  241. 241.
    Howlin, K.J., Alpern, R.J., Berry, C.A., and Rector, F.C., Jr., 1986, Evidence for electroneutral sodium chloride transport in rat proximal convoluted tubule, Am. J. Physiol. 250:F644–F648.PubMedGoogle Scholar
  242. 242.
    Warnock, D.G. and Eveloff, J., 1982, NaCl entry mechanisms in the luminal membrane of renal tubule, Am. J. Physiol. 242:F561–F574.PubMedGoogle Scholar
  243. 243.
    Baum, M. and Berry, C.A., 1984, Evidence for neutral transcellular NaCl transport and neutral basolateral chloride exit in the rabbit proximal convoluted tubule, J. Clin. Invest. 74:205–211.PubMedGoogle Scholar
  244. 244.
    Baum, M., 1987, Evidence that parallel Na+-H + and CI~-HCO~3(OH~) antiporters transport NaCl in the proximal tubule, Am. J. Physiol. 252:F338–F345.PubMedGoogle Scholar
  245. 245.
    Rector, F.C., Jr., 1983, Sodium, bicarbonate, and chloride absorption by the proximal tubule, Am. J. Physiol. 244:F461–F471.PubMedGoogle Scholar
  246. 246.
    Cantiello, H.F., Scott, J.A., and Rabito, C.A., 1987, Conductive Na+ transport in an epithelial cell line (LLC-PKj) with characteristics of proximal tubular cells, Am. J. Physiol. 252:F590–F597.PubMedGoogle Scholar
  247. 247.
    Harris, R.C., Seifter, J.L., and Lechene, C., 1986, Coupling of Na-H exchange and Na-K pump activity in cultured rat proximal tubule cells, Am. J. Physiol. 251:C815–C824.PubMedGoogle Scholar
  248. 248.
    Yang, W.C., Arruda, J.A.L., and Taylor, Z., 1987, Na+-H+ antiporter in posthypercapnic state, Am. J. Physiol. 253:F833–F840.PubMedGoogle Scholar
  249. 249.
    Weinman, E.J., Shenolikar, S., and Kahn, A.M., 1987, cAMP-associated inhibition of Na+- H + exchanger in rabbit kidney brush-border membranes, Am. J. Physiol. 252:F19–F25.PubMedGoogle Scholar
  250. 250.
    Rocco, V.K., Cragoe, E.J., Jr., and Warnock, D.G., 1987, N-ethoxycarbonyl-2-ethoxy-l,2- dihydroquinoline, amiloride analogues, and renal Na+/H+ antiporter, Am. J. Physiol. 252:F517–F524.PubMedGoogle Scholar
  251. 251.
    Bidet, M., Merot, J., Tauc, M., and Poujeol, P., 1987, Na+-H+ exchanger in proximal cells isolated from kidney. II. Short-term regulation by glucocorticoids, Am. J. Physiol. 253:F945–F951.PubMedGoogle Scholar
  252. 252.
    Ichikawa, I. and Kon, V., 1986, Role of peritubular capillary forces in the renal action of carbonic anhydrase inhibitor, Kidney Int. 30:828–835.PubMedGoogle Scholar
  253. 253.
    Johnston, J.R., Brenner, B.M., and Hebert, S.C., 1987, Uninephrectomy and dietary protein affect fluid absorption in rabbit proximal straight tubules, Am. J. Physiol. 253:F222–F233.PubMedGoogle Scholar
  254. 254.
    Beach, R.E., Schwab, S.J., Brazy, P.C., and Dennis, V.W., 1987, Norepinephrine increases Na+-K+ -ATPase and solute transport in rabbit proximal tubules, Am. J. Physiol. 252:F215–F220.PubMedGoogle Scholar
  255. 255.
    Dominguez, J.H., Snowdowne, K.W., Freudenrich, C.C., Brown, T., and Borle, A.B., 1987, Intracellular messenger for action of angiotensin II on fluid transport in rabbit proximal tubule, Am. J. Physiol. 252:F423–F428.PubMedGoogle Scholar
  256. 256.
    Kaskel, F.J., Kumar, A.M., Lockhart, E.A., Evan, A., and Spitzer, A., 1987, Factors affecting proximal tubular reabsorption during development, Am. J. Physiol. 252:F188–F197.PubMedGoogle Scholar
  257. 257.
    Hebert, S.C. and Andreoli, T.E., 1984, Control of NaCI transport in the thick ascending limb, Am. J. Physiol. 246:F745–F756.PubMedGoogle Scholar
  258. 258.
    Molony, D.A., Reeves, W.B., and Andreoli, T.E., 1987, Some transport characteristics of mammalian renal diluting segments, Mineral Electrolyte Metab. 13:442–450.Google Scholar
  259. 259.
    Molony, D.A., Reeves, W.B., Hebert, S.C., and Andreoli, T.E., 1987, ADH increases apical Na+ K+, 2C1~ entry in mouse medullary thick ascending limbs of Henle, Am. J. Physiol. 252: F177–F187.PubMedGoogle Scholar
  260. 260.
    Elalouf, J-M., Sari, D.C., Roinel, N., and De Rouffignac, C., 1987, NaCI and Ca delivery at the bend of rat deep nephrons decreases during antidiuresis, Am. J. Physiol. 252:F1055–F1064.PubMedGoogle Scholar
  261. 261.
    Tabei, K. and Imai, M., 1987, K transport in upper portion of descending limbs of long-loop nephron from hamster, Am. J. Physiol. 252:F387–F392.PubMedGoogle Scholar
  262. 262.
    Haas, M. and Forbush, B., III., 1987, Na, K, Cl-cotransport system: Characterization by bumetanide binding and photolabelling, Kidney Int. 32(23)S134–S140.Google Scholar
  263. 263.
    Scherzer, P., Wald, H., and Popovtzer, M.M., 1987, Enhanced glomerular filtration and Na+- K + -ATPase with furosemide administration, Am. J. Physiol. 252:F910–F915.PubMedGoogle Scholar
  264. 264.
    Taniguchi, J., Tabei, K., and Imai, M., 1987, Profiles of water and solute transport along longloop descending limb: analysis by mathematical model, Am. J. Physiol. 252:F393–F402.PubMedGoogle Scholar
  265. 265.
    Ellison, D.H., Velazquez, H., and Wright, F.S., 1987, Mechanisms of sodium, potassium and chloride transport by the renal distal tubule, Mineral Electrolyte Metab. 13:422–432.Google Scholar
  266. 266.
    Ellison, D.H., Velazquez, H., and Wright, F.S., 1987, Thiazide-sensitive sodium chloride cotransport in early distal tubule, Am. J. Physiol. 253:F546–F554.PubMedGoogle Scholar
  267. 267.
    Velazquez, H., Ellison, D.H., and Wright, F.S., 1987, Chloride-dependent potassium secretion in early and late renal distal tubules, Am. J. Physiol. 253:F555–F562.PubMedGoogle Scholar
  268. 268.
    Schnermann, J., Steipe, B., and Briggs, J.P., 1987, In situ studies of distal convoluted tubule in rat. II.K secretion, Am. J. Physiol. 252:F970–F976.Google Scholar
  269. 269.
    O’Neil, R.G. and Sansom, S.C., 1984, Characterization of apical cell membrane Na + and K + conductances of cortical collecting duct using microelectrode techniques, Am. J. Physiol. 247: F14–F24.PubMedGoogle Scholar
  270. 270.
    Koeppen, B.M., 1985, Conductive properties of the rabbit outer medullary collecting duct: Inner stripe, Am. J. Physiol. 248:F500–F506.PubMedGoogle Scholar
  271. 271.
    Schuster, V.L. and Stokes, J.B., 1987, Chloride transport by the cortical and outer medullary collecting duct, Am. J. Physiol. 253:F203–F212.PubMedGoogle Scholar
  272. 272.
    Cupples, W.A. and Sonnenberg, H., 1987, Load dependency of sodium chloride reabsorption by medullary collecting duct in rat, Am. J. Physiol. 253:F642–F648.PubMedGoogle Scholar
  273. 273.
    Sonnenberg, H., Honrath, U., and Wilson, D.R., 1987, Effects of amiloride in the medullary collecting duct of rat kidney, Kidney Int. 31: 1121–1125.PubMedGoogle Scholar
  274. 274.
    Sands, J.M., Nonoguchi, H., and Knepper, M.A., 1987, Vasopressin effects on urea and H2O transport in inner medullary collecting duct subsegments, Am. J. Physiol. 253:F823–F832.PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Ali A. Khraibi
    • 1
  • Franklyn G. Knox
    • 1
  1. 1.Departments of Physiology and Biophysics, and MedicineMayo Medical School, Mayo FoundationRochesterUSA

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