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Coronaviruses

  • Arnold S. Monto
Chapter

Abstract

Coronaviridae are a monogeneric family of RNA-containing agents that have been associated with respiratory illnesses in man and with a number of other diseases in laboratory and domestic animals. The name for the family was adopted to describe the characteristic fringe of crownlike projections seen around the viruses by electron microscopy; these projections are club-shaped rather than sharp or pointed as is the case with the myxoviruses. Like the myxoviruses, the coronaviruses contain essential lipids and are 80–160 nm in diameter.(23)Unlike them, the coronaviruses are positive stranded.(57,69)Whereas the animal strains are readily isolated in several different systems, recovery of the human strains has posed major problems. A number of these strains have been isolated only in organ culture of the human respiratory tract. This factor has made it difficult to determine the relationship among isolates and has complicated efforts to understand the role of these viruses in human respiratory illness. Therefore, much of the information on the epidemiology of the agents has come from serological studies.

Keywords

Infectious Bronchitis Virus Mouse Hepatitis Virus Human Coronavirus Coronavirus Infection Human Coronaviruses 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Arnold S. Monto
    • 1
  1. 1.Departments of Epidemiology and International Health, School of Public HealthUniversity of MichiganAnn ArborUSA

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