Three-Dimensional Morphology of Striatal Neurons in Relation to Compartmental Organization of the Striatum

  • Jérôme Yelnik
  • Chantal François
  • Gérard Percheron
Part of the Advances in Behavioral Biology book series (ABBI, volume 41)


The existence of a compartmentation of the striatum suggests that this neuronal set consists of different subdivisions, namely the striosomes and matrix (Graybiel and Ragsdale, 1978), which could process separately different types of information. Characteristically, this occurs in tight neuronal set-spaces (see Percheron et al. in this volume) which can constitute either closed or open nuclei according to whether the dendrites of their neurons cross or do not cross their cytoarchitectonic boundaries (Mannen, 1960). In the case of striatal compartmentation, the spatial organization of the dendrites of striatal neurons is crucial since it determines whether striosomes and matrix are informationally closed or open compartments.


Cholinergic Neuron Striatal Neuron Dendritic Arborization Compartmental Boundary Total Dendritic Length 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Arts, M.P.M., and Groenewegen, H.J., 1992, Relationships of the dendritic arborizations of ventral striatomesencephalic projection neurons with boundaries of striatal compartments. An in vitro intracellular labelling study in the rat, Europ. J. Neurosci. 4:574–588.CrossRefGoogle Scholar
  2. Bolam, J.P., Izzo, P.N., and Graybiel, A.M., 1988, Cellular substrate of the histochemically defined striosome/matrix system of the caudate nucleus:a combined Golgi and immunocytochemical study in cat and ferret, Neuroscience 24:853–875.PubMedCrossRefGoogle Scholar
  3. Bolam, J.P., Wainer, B.H., and Smith, A.D., 1984, Characterization of cholinergic neurons in the rat neostriatum. A combination of choline acetyltransferase immunocytochemistry, Golgi-impregnation and electron microscopy, Neuroscience 12:711–718.PubMedCrossRefGoogle Scholar
  4. Braak, H., and Braak, E., 1982, Neuronal types in the striatum of man, Cell Tissue Res. 227:319–342.PubMedCrossRefGoogle Scholar
  5. Chang, H.T., Wilson, C.J. and Kitai, S.T., 1982, A Golgi study of the rat neostriatal neurons:light microscopic analysis, J. Comp. Neurol. 208:107–126.PubMedCrossRefGoogle Scholar
  6. DiFiglia, M., 1987, Synaptic organization of cholinergic neurons in the monkey neostriatum, J. Comp.Neurol. 255:245–258.PubMedCrossRefGoogle Scholar
  7. DiFiglia, M., Pasik, P., and Pasik, T., 1976, A Golgi study of neuronal types in the neostriatum of monkeys, Brain Res. 114:245–256.PubMedCrossRefGoogle Scholar
  8. François, C, Percheron, G., Yelnik, J., and Heyner, S., 1979, Demonstration of the existence of local circuit neurons in the Golgi–stained primate substantia nigra, Brain Res. 172:160–164.PubMedCrossRefGoogle Scholar
  9. François, C, Yelnik, J., and Percheron, G., 1987, Golgi study of the primate substantia nigra II. Spatial organization of dendritic arborizations in relation to the cytoarchitectonic boundaries and to the striatonigral bundle, J. Comp. Neurol. 265:473–493.PubMedCrossRefGoogle Scholar
  10. Graveland, G.A., Williams, R.S., and DiFiglia, M., 1985, A Golgi study of the human neostriatum:neurons and afferent fibers, J. Comp. Neurol. 34:317–333.CrossRefGoogle Scholar
  11. Graybiel, A.M., and Ragsdale, C.W. Jr., 1978, Histochemically distinct compartments in the striatum of human, monkey and cat demonstrated by acetylcholinesterase staining, Proc. Natl. Acad. Sci. U.S.A. 75:5723–5726.PubMedCrossRefGoogle Scholar
  12. Kawaguchi, Y., 1992, Large aspiny cells in the matrix of the rat neostriatum in vitro:physiological identification, relation to the compartments and excitatory postsynaptic currents, J. Neurophysiol. 67:1669–1682.PubMedGoogle Scholar
  13. Kawaguchi, Y., Wilson, C.J., and Emson, P.C., 1989, Intracellular recording of identified neostriatal patch and matrix spiny cells in a slice preparation preserving cortical inputs, J. Neurophysiol 62:1052–1068.PubMedGoogle Scholar
  14. Mannen, H., 1960, «Noyau fermé» et «noyau ouvert», Arch. Ital. Biol. 98:333–350.Google Scholar
  15. Penny, G.R., Wilson, C.J., and Kitai, ST., 1988, Relationship of the axonal and dendritic geometry of spiny projection neurons to the compartmental organization of the neostriatum, J. Comp. Neurol 269:275–289.PubMedCrossRefGoogle Scholar
  16. Percheron, G., 1982, Principles and methods of the graph-theoretical analysis of natural binary arborescences,. J. Theoret. Biol. 99:509–552.CrossRefGoogle Scholar
  17. Percheron, G., François, C, Yelnik, J., Fénelon, G., and Talbi, B., 1993, The basal ganglia related system (or cortico-baso-thalamo-cortical system) of primates. Definition, description and informational analysis. Affinity for “patchy” patterns, in:“The Basal Ganglia IV — New Ideas and Data on Structure and Function”, G. Percheron, J.S. McKenzie, and J. Féger, eds, Plenum Press, New York.Google Scholar
  18. Yelnik, J., François, C, Percheron, G., and Heyner, S., 1987, Golgi study of the primate substantia nigra I.Quantitative morphology and typology of nigral neurons, J. Comp. Neurol. 265:455–472.PubMedCrossRefGoogle Scholar
  19. Yelnik, J., François, C, Percheron, G., and Tandé, D., 1991a, Morphological taxonomy of the neurons of the primate striatum, J. Comp. Neurol. 313:273–294.PubMedCrossRefGoogle Scholar
  20. Yelnik, J., Francois, C, Percheron, G., Lemonnier, E., 1991b, Cholinergic neurons of the rat and primate striatum are morphologically different, in: “Chemical Signalling in the Basal Ganglia”, Satellite Symposium of the 14th meeting of the European Neuroscience Association, Babraham, Cambridge, 7-8 septembre 1991, Abstr. p3.Google Scholar
  21. Yelnik, J., Percheron, G., and François, C, 1984, A Golgi analysis of the primate globus pallidus. II.Quantitative morphology and spatial orientation of dendritic arborizations, J. Comp. Neurol. 227:200–213.PubMedCrossRefGoogle Scholar
  22. Yelnik, J., Percheron, G., François, C, and Burnod, Y., 1983, Principal component analysis:A suitable method for the three-dimensional study of the shape, dimensions and orientation of dendritic arborizations, J. Neurosci. Methods 9:115–125.PubMedCrossRefGoogle Scholar
  23. Yelnik, J., Percheron, G., Perbos, J., and François, C, 1981, A computer-aided method for the quantitative analysis of dendritic arborizations reconstructed from serial sections, J. Neurosci. Methods 4:347–364.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1994

Authors and Affiliations

  • Jérôme Yelnik
    • 1
  • Chantal François
    • 1
  • Gérard Percheron
    • 1
  1. 1.Laboratoire de Neuromorphologie Informationnelle et de Neurologie Expérimentale du Mouvement INSERM U106Hôpital de la SalpêtrièreParis Cedex 13France

Personalised recommendations