Effect of Route of Administration on the Metabolism of Quinolinic Acid-6*14C in Animals

  • L. V. Hankes
  • M. Schmaeler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 398)

Abstract

After a study of quinolinic acid metabolism in patients with pellagra (Hankes et al., 1992), a study was done to determine the effect of route of administration of the labeled compound on its metabolism in an animal species which had an intestinal synthesis in a ceacum.

Keywords

Nicotinic Acid Quinolinic Acid Label Compound Rapid Absorption Picolinic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Hankes, L.V., De Bruin, E., Jansen, C. R., Vorster, L., and Schmaeler, M., 1977, South African Med. Jour. 51: 383.Google Scholar
  2. Hankes, L.V., Hugo, N., Jansen, C. R., and Schmaleler, M., 1992, Metabolism of quinolinic acid-6-14C, in Bantu with pellagra, in: Advances in Tryptophan Research, Ishiguro I., Kido R., Nagatsu T., Nagamura Y., Ohta Y., eds., Fujita Health University Press, Toyoake, pp 269–272.Google Scholar
  3. Mahin, D.T., and Lofberg, R.T., 1966, A simplified method of sample preparation for determination of tritium, carbon-14, or sulfur-35 in blood or tissue by liquid scintillation counting, Anal Biochem. 16: 500.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • L. V. Hankes
    • 1
  • M. Schmaeler
    • 1
  1. 1.Med. Res. Center Brookhaven Natl. LabUptonUSA

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