Advertisement

Biochemical Studies On The Effect of Plotosus Lineatus Crude Venom (In Vivo) And Its Effect On Eac-Cells (In Vitro)

  • Fawzia A. Fahim
  • Essam A. Mady
  • Samira M. Ahmed
  • M. A. Zaki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 391)

Abstract

The oriental catfish, Plotosus lineatus, is one of the most dangerous venomous fishes known which occasionally causes death (Halstead, 1978). This fish is responsible for approximately many hundreds of envenomation to fishermen during handling in Suez Gulf and Red Sea. The envenomation, from P. lineatus, resulted in severe pain, numbness, fever, weakness, nausea, local paralysis and dizziness. In extreme cases there may be a massive edema involving the entire limb and gangrene of the area around wounds (Shiomi et al, 1986, 1987 and 1988 and Zerman, 1989).

Keywords

Sublethal Dose Venom Gland Skin Secretion Median Lethal Dose Crude Venom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Al-Hassan, J. M.; Thomoson, M. and Criddle, R. S. (1982). Composition of the proteinaceous gel secretion from the skin of the Arabian Gulf catfish (Arius, thalassinus). Mar. Biol., 70: 27.Google Scholar
  2. Al-Hassan, J. M.; Ali, M.; Thomson, M.; Fatima, T. and Gubler, C. J (1985a). Toxic effect of the soluble skin secretion from the Arabian Gulf catfish (Arius. thalassinus)on plasma and liver enzyme levels. Toxicon., 23: 532.CrossRefGoogle Scholar
  3. Al-Hassan, J. M.; Ali, M.; Thomson, M.; Fatima, T; Gubler, C. J Criddle, R. S. and Summers, B. (1985b). Catfish epidermal secretions in response to threat or injury: A novel defense response. Mar. Biol., 88: 117.Google Scholar
  4. Al-Hassan, J. M.; Ali, M.; Thomson, M.; Fatima, T; Gubler, C. J and Criddle, R. S. (1987a). Prostaglandin associated mortality following intravenous injection of catfish epidermal secretions in rabbits. Prostaglandins, Leukotrienes. Med., 28: 95.Google Scholar
  5. Al-Hassan, J. M.: Thomson, M.; Ali, M. and Criddle, R. S. (1987b). Toxic and pharmacologically active secretions from the Arabian Gulf catfish (Arius. thalassinus Ruppell),. J. Toxicol.-Toxin Rev., 6:1.Google Scholar
  6. Ali, M.; Thomson, M.: Al-Hassan, J. M.; Al-Saleh, J.:Fayad, S.; Assad, H. and Criddle, R. S. (1989). Comparative biochemical and pharmacological properties of epidermal secretion from Ariid catfish of the Arabian Gulf. Comp. Biochem. Physiol., 92B: 205.Google Scholar
  7. Al-Lahham; Al-Hassan, J. M.; Thomson, M.; and Criddle, R. S. (1987). A hemolytic protein secreted from epidermal cells of the Arabian Gulf catfish Arius. thalassinus (Ruppell). Comp. Biochem. Physiol., 87B: 321.Google Scholar
  8. Al-Naqeeb, M. A.; AI-Hassan, J. M.; Ali, M.; Thomson, M. and Criddle, R. S. (1989). Histopathological observations on organs from rabbits injected with the skin toxin of the Arabian Gulf catfish Arius. thalassinus, Valenciennes). Toxicon., 27: 789.CrossRefGoogle Scholar
  9. Belfield, A. and Golderg, D. M. (1971). Revised assay for serum alkaline phosphatase activity using 4-amino antipyrine. Enzyme., 12: 561.PubMedGoogle Scholar
  10. Birkhead, W. E. (1972). Toxicity of stings of Ariidand Ictaluridcatfish. Copeia. 1972: 790.CrossRefGoogle Scholar
  11. Cabaud, P; Wroblewski, F. and Ruggiero, V. (1958). Calorimetrie measurement of lactate dehydrogenase activity of body fluids. Am. J. Clin. Pathol., 30: 234.PubMedGoogle Scholar
  12. Datta, A; Gomes, A.; Sarangi, B.; Kar, P. K. and Lahiri, S. C. (1982). Parmacodynamic actions of crude venom of the Indian catfish (Hetropneustes fossilis). Indian J. Med. Res., 76: 829.Google Scholar
  13. Ellman, G. L.; Courtney, K. D.; Anders, V. J. and Featger stone, R. M. (1961). A new and rapid calorimetrie determination of acetyl Cholinesteraseactivity. Biochem. Pharmacol., 7: 88.Google Scholar
  14. Fahim, F. A. and Zahran, F. I. (1987). Effect of the most lethal fraction (F. Ill) of Naja nigricollisvenom: part I: on liver function, ppl73. 12th international Congress for Statistic, Computer Science, Social and demographic research center. Ain Shams University, Cairo, Egypt.Google Scholar
  15. Fahim, F. A.; Zahran, F. I. and Mady, E. A. (1988). Effect of Nnigricollis venom and its fraction on EAC-cells in mice. The first Inter. Conf. (Feb. 15, 1988). The Egypt. Soc. of Tumor Markers Oncology.Google Scholar
  16. Fisher, G. H. and Yates, F. (1943). Tests of significance based on the normal distraction. In: Statistical tables for biological, agricultural and medical research. Oliver and Boyd. Edinberg and London.Google Scholar
  17. Goldin, A.; Carter, S. and Mantel, N. (1974). In: Antineoplastic and Immunosuppressive Agents. Eds. Sartorelli, A and John, D. G., Springer Verlag. Berlin Heidelberg. New York. Part 1. 12.Google Scholar
  18. Grunbaum, H. G. and Grunbaum, A. S. (1911). Lancet 1:879.Google Scholar
  19. Hald, P. M. (1951). Determination of sodium and potassium ions with flame photometric method. In: Medical research. Vol. IV: 79.Google Scholar
  20. Halstead, B.W. (1978). Venomous catfish. In: Venomous and poisonous marine animals of world. Vol. 3, Government printing office, Washington, DC.Google Scholar
  21. Jendrassik, L. and Grof, P. (1983). A calorimetrie method for bilirubin determination. Bioch. J., 297: 81.Google Scholar
  22. Khoo, H. E.; Yuen, R.; Poh, C. H. and Tann, C. H. (1992). Biological activities of Synanceja hórrida (stonefish) venom. Nat. Toxins., 1: 54.CrossRefGoogle Scholar
  23. Knight, J. A.; Anderson, S. and Rauk, J. M. (1972). Chemical basis of the Sulfo-Phosphovanillin reaction for estimating total serum lipids. Clin. Chem., 18: 199.Google Scholar
  24. Larsen, J. B. and Price, W. J. Jr. (1978). Some physiological effects of fractionated jelly fish toxins. Toxicon (suppl)., 1: 517.Google Scholar
  25. Mansour, M. A.; Abdel-Hamid, M. E.; Ramadan, M. A. and Al-Nagy, S. A. (1980). Physicochemical studies on the protein and mineral metabolism in rabbits poisoned by Arthron hispidustetrodotoxin. Ann. Zool., 16: 139.Google Scholar
  26. Marsh, W. H.; Fringerhut, B. and Miller, H. (1965). Determination of serum urea by diaoxal method. In: Practical clinical biochemistry, 5th (edn) by Varley London.Google Scholar
  27. Martin, D. W. (1983). Blood plasma and clotting. In: Harper–s review of Biochemistry, pp.635,20th ed. Medical publication, Los Anglos, California.Google Scholar
  28. Nair, R. B. (1981). Effect of sublethal dose of toxic protein isolated from venom of the scorpion Heterometrus scaber. Indian J. Exp. Biol., 19: 103.Google Scholar
  29. Quick, A. J. (1940). Thromboplastin reagent for the determination of prothrombin time. Science. 92: 113.Google Scholar
  30. Ramadan, M. A.; Tash, F. M.; Al-Nagdy, S. A.; Mahdy, Z. and Mansour, M. A. (1980). Effect of the toxin extracted from the Red Sea Fish Arthron hispiduson the metabolism of carbohydrates and lipid metabolism. Zool. Soc. Egypt. Bull., 22: 22.Google Scholar
  31. Reed, L. J. and Meuench, H. (1938). A simple method for estimated fifty percent end points. Amer. J. Hygi., 37: 493.Google Scholar
  32. Reitman, S. and Frankle, S. (1957). A colorimeteric method for the determination of glutamic oxaloacetic & glutamic pyruvate transaminase. Am. J. Clin. Pathol, 28: 56.PubMedGoogle Scholar
  33. Seifter, S.; Dayton, S.; Novic, B. and Muntmyler, E. (1950). Estimation of glycogen with the anthrone reagent. Arch. Biochem., 25: 291.Google Scholar
  34. Sellei, C. C; Eckhardt, S. and Mette, L. (1970). In: Chemotherapy of neoplastic disease, Academy, Kado, Budapest.Google Scholar
  35. Shiomi, K.; Takamiya, M.; Yamanaka, H.; Kikuch, T. and Konno, K. (1986). Short communications: Hemolytic, lethal and edema forming activities of the skin secretion from the oriental catfish (Plotosus lineatus). Toxicon. 24: 1015.PubMedCrossRefGoogle Scholar
  36. Shiomi, K.; Takamiya, M., Yamanaka, H. and kikuch, T. (1987). Purification of lethal factor in the skin secretion from the oriental catfish (Plotosus lineatus). Toxicon 53: 1275.Google Scholar
  37. Shiomi, K.; Takamiya, M., Yamanaka, H. and kuch, T. and Susuki, Y. (1988). Toxins in the skin secretion of the oriental catfish (Plotosus lineatus): Immunological properties and immunocychemical identification of producing cells. Toxicon 26: 353.PubMedCrossRefGoogle Scholar
  38. Scasz, G. (1969). A kinetic photometric method for serum GGT. Clin. Chem., 15: 124.Google Scholar
  39. Trinder, P. (1969). Determination of glucose in blood using glucose oxidase with an alternative oxygen receptor Ann. Clin. Biochem. 6: 24.Google Scholar
  40. Varley, H.; Gowenlock, A. H. and Bell, M. (1980). Practical clinical Biochemistry. Vol. I. General topics and commoner test. 5th William Heinmann medical books LTD. London.Google Scholar
  41. Weichelbaum, T.E. (1946). An accurate and rapid method for the determination of proteins in small amounts of blood and plasma. Am. J. Clin. Path. Tech. Sec., 10: 4.Google Scholar
  42. Zerman, M.G. (1989). Catfish Strings, A report of 3 cases. Ann. Emerg Med, 18: 211.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Fawzia A. Fahim
    • 1
  • Essam A. Mady
    • 1
  • Samira M. Ahmed
    • 2
  • M. A. Zaki
    • 2
  1. 1.Department of BiochemistryFaculty of Science Ain Shams UniversityCairoEgypt
  2. 2.National Institute of Oceanography and FisheriesEgypt

Personalised recommendations