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The Metastasis of Human Teratomas

  • Chapter
The Human Teratomas

Part of the book series: Contemporary Biomedicine ((CB,volume 3))

Abstract

The increasingly successful treatment protocols for gonadal and extragonadal malignant germ cell tumors (MGCT), in particular nonseminomatous germ cell tumors (NSGCT), have stimulated careful clinical and pathological staging (Whitmore, 1979; Vugrin et al., 1979a; Hussey, 1981; Einhorn, 1981), and provided new data on the pattern of metastasis of these neoplasms. Moreover, the gradual acceptance of a more uniform histological classification of germ cell tumors (GCT) regardless of their site of origin (Serov and Scully, 1973; Mostofi, 1977b; Brodeur et al., 1981) has made a review of the recent literature on metastasis of these tumors more feasible.

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References

  • Altman RP, Randolph JG, Lilly JR (1974) Sacrococcygeal teratoma: American Academy of Pediatrics Surgical Section Survey-1973. J Pediatr Surg 9:389–398.

    PubMed  CAS  Google Scholar 

  • Baer W, Hedinger C (1976) Comparison of histologic types of primary testicular germ cell tumors with their metastases. Consequences for the WHO and the British nomenclatures? Virchows Arch A 370:41–54

    Google Scholar 

  • Beattie EJ (1979) Mediastinal germ cell tumors (surgery). Semin Oncol 6:109–112

    PubMed  Google Scholar 

  • Bagshaw MA, McLaughlin WT, Earle JD (1969). Definitive radiotherapy of primary mediastinal seminoma. Am J Roentgenol 105:86–94

    CAS  Google Scholar 

  • Bale PM, Painter DM, Cohen D (1975) Teratomas in childhood. Pathology 7:209–218

    PubMed  CAS  Google Scholar 

  • Benjamin F, Rorat E (1975) Solid ovarian teratoma with peritoneal and abdominal implants, progressive in vivo maturation, and probable cure. Gynecol Oncol 3:308–313

    PubMed  CAS  Google Scholar 

  • Bergman F (1966) Carcinoma of the ovary. A clinicopathological study of 86 autopsied cases with special reference to mode of spread. Acta Obstet Gynecol Scand 45:211–231

    PubMed  CAS  Google Scholar 

  • Bosl AJ, Vogelzang NJ, Goldman A, Fraley EE, Lange PH, Levitt SH, Kennedy BJ (1981) Impact of delay in diagnosis on clinical stage of testicular cancer. Lancet 2:970–973

    PubMed  CAS  Google Scholar 

  • Borski AA (1973) Diagnosis, staging and natural history of testicular tumors. Cancer 32:1202–1205

    PubMed  CAS  Google Scholar 

  • Brodeur GM, Howarth CB, Pratt CB, Caces J, Hustu O (1981) Malignant germ cell tumors in 57 children and adolescents. Cancer 48:1890–1898

    PubMed  CAS  Google Scholar 

  • Carr I, Carr J (1980) Experimental lymphatic invasion and metastasis. In Weiss L, Gilbert HA, Ballon SC (eds) Lymphatic System Metastasis. Hall, Boston, pp. 41–73

    Google Scholar 

  • Castaldo TW, Petrilli ES, Ballon SC, Berman ML (1980) Lymph node metastases from epithelial carcinoma of the ovary. In Weiss L, Gilbert HA, Ballon SC (eds). Lymphatic System Metastasis. Hall, Boston pp 383–389

    Google Scholar 

  • Chait MM, Kurtz RC, Hajdu SI (1978) Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis. Am J Dig Dis 23:925–928

    PubMed  CAS  Google Scholar 

  • Cheng E, Cvitkovic E, Wittes RE, Golbey RB (1978) Germ cell tumors (II) VAB II in metastatic testicular cancer. Cancer 42:2162–2168

    PubMed  CAS  Google Scholar 

  • Cox JD (1975) Primary malignant germinal tumors of the mediastinum; a study of 24 cases. Cancer 36:1162–1168

    PubMed  CAS  Google Scholar 

  • Di Saia PJ, Saltz A, Kagan AR, Morrow CP (1977) Chemotherapeutic retroconversion of immature teratoma of the ovary. Obstet Gynecol 49:346–350

    Google Scholar 

  • Einhorn LH, Donohue J (1977) cis-Diamminodichloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Int Med 87:293–298

    PubMed  CAS  Google Scholar 

  • Einhorn LH (1981) Testicular cancer as a model for a curable neoplasm: The Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res 41:3275–3280

    PubMed  CAS  Google Scholar 

  • Einhorn LH, Williams SD, Mandelbaum I, Donohue JP (1981) Surgical resection in disseminated testicular cancer following chemotherapeutic cytoreduction. Cancer 48:904–908

    PubMed  CAS  Google Scholar 

  • Exelby PR (1980) Testicular cancer in children. Cancer 45:1803–1809

    PubMed  CAS  Google Scholar 

  • Feldman GB (1975) Lymphatic obstruction in carcinomatous ascites. Cancer Res 35:325–329

    PubMed  CAS  Google Scholar 

  • Fidler IJ (1973) The relationship of embolic heterogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer 9:223–227

    PubMed  CAS  Google Scholar 

  • Fidler IJ (1978) Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 38:2651–2660

    PubMed  CAS  Google Scholar 

  • Fidler IJ, Kripke ML (1977) Metastasis results from preexisting variant cells within a malignant tumor. Science 197:893–895

    PubMed  CAS  Google Scholar 

  • Fidler IJ, Gruys E, Citone MA, Barnes Z, Bucana C (1981) Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin. J Natl Cancer Inst 67:947–953

    PubMed  CAS  Google Scholar 

  • Fosså SD, Klepp O, Elgjo RF, Eliassen G, Melsom H, Urnes T, Wang M (1981) The effect of patient’s delay and doctor’s delay in patients with malignant germ cell tumors. In: Skakkebaek NE, Berthelsen JG, Grigor KM, Visfeldt J (eds). Early Detection of Testicular Cancer. Scriptor, Copenhagen, pp 134–144

    Google Scholar 

  • Fox H, Langley FA (1976) Tumors of the Ovary. Heinemann, London, pp 172–261

    Google Scholar 

  • Fraley EE, Lange PH, Williams RD, Ortlip SA (1980). Staging of early nonseminomatous germ-cell testicular cancer. Cancer 45:1762–1767

    PubMed  CAS  Google Scholar 

  • Grosfeld JL, Ballantine TVN, Lowe D, Baehner RL (1976) Benign and malignant teratomas in children: Analysis of 85 patients. Surgery 80:297–305

    PubMed  CAS  Google Scholar 

  • Haimovic IC, Sharer L, Hyman RA, Beresford HR (1981) Metastasis of intracranial germinoma through a ventriculoperitoneal shunt. Cancer 48:1033–1036

    PubMed  CAS  Google Scholar 

  • Hermanek P (1977) Testicular cancer, histologic classification and staging, topography of lymph node metastases. Recent Results Cancer Res 60:202–211

    PubMed  Google Scholar 

  • Higgins CC, Buchert WI (1939) Malignant tumors of the testicle. A review of 83 cases. Am J Surg 43:675–687

    Google Scholar 

  • Hong WK, Wittes RE, Hajdu ST, Cvitkovic E, Whitmore WF, Golbey RB (1977) The evolution of mature teratoma from malignant testicular tumors. Cancer 40:2987–2992

    PubMed  CAS  Google Scholar 

  • Hultén L, Kindblom LG, Lindhagen J, Rosencrantz M, Seeman T, Wahlquist L (1973) Funicular and pedal lymphography in testicular tumors. Acta Chir Scand 139:746–758

    PubMed  Google Scholar 

  • Hussey DH (1981) A comparison of treatment methods for germinal cell tumors of the testis other than pure seminoma. Radiology 139:181–188

    PubMed  CAS  Google Scholar 

  • Jewett MAS, Whitmore WF (1976) Adult teratoma of the testis metastasizing as adult teratoma: case report and review of literature (letter). J Urol 115:342

    PubMed  CAS  Google Scholar 

  • Johnson DE, Appelt G, Samuels ML, Luna M (1976) Metastases from testicular carcinoma. Urology 8:234–239

    PubMed  CAS  Google Scholar 

  • Jonsson K, Wallace S, Jing BS, Boyle LE, Johnson DE (1978) Lymphangiography in patients with malignancy in a non-descended testicle. J Urol 119:614–617

    PubMed  CAS  Google Scholar 

  • Julian CG, Goss J, Blanchard K, Woodruff JD (1964) Biologic behaviour of primary ovarian malignancy. Obstet Gynecol 44:873–884

    Google Scholar 

  • Kahan B (1979) Ovarian localization of embryonal teratocarcinoma cells derived from female germ cells. Somat Cell Genet 5:763–780

    PubMed  CAS  Google Scholar 

  • Kaye SB, Bagshaw KD, McElwain TJ, Peckham MJ (1979) Brain metastases in malignant teratoma: a review of four years’s experience and an assessment of the role of tumor markers. Brit J Cancer 39:217–223

    PubMed  CAS  Google Scholar 

  • Kedia K, Fraley EE (1975) Adult teratoma of the testis metastasizing as adult teratoma: a case report and review of literature. J Urol 114:636–639

    PubMed  CAS  Google Scholar 

  • Kennedy BJ, Griffen WO, Lober P (1965) Specific effect of mithramycin on embryonal carcinoma of the testis. Cancer 18:1631–1636

    PubMed  CAS  Google Scholar 

  • Kleinsmith LJ, Pierce GB (1964) Multipotentiality of single embryonal carcinoma cells. Cancer Res 24:1544–1552

    PubMed  CAS  Google Scholar 

  • Kripke ML, Gruys E, Fidler IJ (1978) Metastatic heterogenity of cells from an ultraviolet light induced murine fibrosarcoma of recent origin. Cancer Res 38:2962–2967

    PubMed  CAS  Google Scholar 

  • Kurman RJ, Norris HJ (1978) Germ cell tumors of the ovary. Pathol Ann 13:291–325

    Google Scholar 

  • Kurokawa Y (1970) Experiments on lymph node metastases by intralymphatic inoculation of rat ascites tumor cells, with special reference to lodgement, passage, and growth of tumor cells in lymph nodes. Gann 61:461–471

    PubMed  CAS  Google Scholar 

  • Lee MS, Hendrickson FR (1978) Analysis of pattern of recurrence in nonseminomatous testicular tumor. Radiology 127:775–777

    PubMed  CAS  Google Scholar 

  • Liotta LA, Kleinerman J, Saidel GM (1976) The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Res 36:889–894

    PubMed  CAS  Google Scholar 

  • Luna MA, Valenzuela-Tamariz J (1976) Germ-cell tumors of the mediastinum, postmortem findings. Am J Clin Pathol 65:450–454

    PubMed  CAS  Google Scholar 

  • Mackenzie AR (1966) Chemotherapy of metastatic testis cancer. Results in 154 patients. Cancer 19:1369–1376

    PubMed  CAS  Google Scholar 

  • McGirr VG, Goldstein AM, Thompson DM, Utley WLF (1977) Testicular tumours: treatment by surgery and radiotherapy. AustNZJ Surg 47:491–495

    PubMed  CAS  Google Scholar 

  • Merrin C, Baumgartner G, Wajsman Z (1975) Benign transformation of testicular carcinoma by chemotherapy. Lancet 1:43–44

    PubMed  CAS  Google Scholar 

  • Mitchell MS (1980) A note on the lymph node as an immunologic barrier. In: Weiss L, Gilbert HA, Ballon SC (eds) Lymphatic System Metastasis, Hall, Boston, pp 74–79

    Google Scholar 

  • Morrow CP (1979) Classification and characteristics of ovarian cancer. Clin Obstet Gynecol 22:925–937

    PubMed  CAS  Google Scholar 

  • Mostofi FK (1973) Testicular tumors. Epidemiologic, etiologic and pathologic features. Cancer 32:1186–1201

    PubMed  CAS  Google Scholar 

  • Mostofi FK (1977a) Epidemiology and pathology of tumors of human testis. Recent Results Cancer Res 60:176–195

    PubMed  Google Scholar 

  • Mostofi FK (1977b) Histological typing of Testis Tumours. World Health Organization, Geneva.

    Google Scholar 

  • Norris HJ, Zirkin HJ, Benson WL (1976) Immature (malignant) teratoma of the ovary. A clinical and pathologic study of 58 cases. Cancer 37:2359–2372.

    PubMed  CAS  Google Scholar 

  • O’Hare MJ (1978) Teratomas, neoplasia and differentiation: a biological overview. I. The natural history of teratomas. Invest Cell Pathol 1:39–63

    PubMed  Google Scholar 

  • Oosterhuis JW, Andrews PW (1982) Effects of Cis-platinum (CDDP) on mouse teratocarcinoma cell lines in vitro: no induction of differentiation; preferential killing of stem cells. Proceedings of the 23rd Dutch Federation Meeting, Abstract 320

    Google Scholar 

  • Oosterhuis JW, Damjanov I (1982) Treatment of primary embryo derived teratocarcinomas in mice with Cis-diammine-dichloroplatinum. Eur J Cancer Clin Oncol (in press)

    Google Scholar 

  • Oosterhuis JW, Fox N, Damjanov I (1982) Maturation of mouse teratocarcinoma treated with Cis-diammine-dichloroplatinum (CDDP) (abstract). Proceedings of the AACR 23:225

    Google Scholar 

  • Oosterhuis JW, Suurmeijer AJH, Sleijfer DTh, Schraffordt-Koops H, Oldhoff J, Fleuren GJ (1982) Effects of multiple drug chemotherapy (Cis-diammine- dichloroplatinum, bleomycin and vinblastine) on the maturation of retroperitoneal lymph node metastases of non-seminomatous germ cell tumors of the testis: no evidence for de novo induction of differentiation. Cancer 23:225

    Google Scholar 

  • Parkinson C, Beilby JOW (1977) Features of prognostic significance in testicular germ cell tumours. J Clin Path 30:113–119

    PubMed  CAS  Google Scholar 

  • Patton JF, Seitzman DN, Zone RA (1960) Diagnosis and treatment of testicular tumors. Am J Surg 99:525–532

    PubMed  CAS  Google Scholar 

  • Peckham MJ (1981a) Investigation and staging: general aspects and staging classification. In: Peckham MJ (ed) The Management of Testicular Tumours. Edward Arnold, London, pp 89–101

    Google Scholar 

  • Peckham MJ (1981b) Non-seminomas: current treatment results and future prospects. In: Peckham MJ (ed) The Management of Testicular Tumours. Edward Arnold, London, pp 218–239

    Google Scholar 

  • Plentl AA, Friedman EA (1971) Lymphatic System of the Female Genitalia. Saunders, Philadelphia

    Google Scholar 

  • Ray B, Hajdu SI, Whitmore WF (1974) Distribution of retroperitoneal lymph node metastases in testicular germinal tumors. Cancer 33:340–348

    PubMed  CAS  Google Scholar 

  • Reynolds TF, Vugrin D, Cvitkovic E, Cheng E, Braun DW, O’Hehir MA, Dukeman ME, Whitmore WF, Golbey RB (1981) VAB-3 combination chemotherapy of metastatic testicular cancer. Cancer 48:888–898

    PubMed  CAS  Google Scholar 

  • Robboy SJ, Scully RE (1970) Ovarian teratoma with glial implants on the peritoneum. Human Pathol 1:643–653

    CAS  Google Scholar 

  • Rosai J, Khodaoust K, Silber I (1969) Spermatocytic seminoma II. Ultrastructural study. Cancer 24:103–116

    PubMed  CAS  Google Scholar 

  • Roth LM, Panganiban WG (1976) Gonadal and extragonadal yolk sac carcinomas. A clinicopathological study of 14 cases. Cancer 37:812–820

    PubMed  CAS  Google Scholar 

  • Rubinstein LJ (1981) Cytogenesis and differentiation of pineal neoplasms. Human Pathol 12:441–448

    CAS  Google Scholar 

  • Sakata K, Yamada H, Sakai N, Hosono Y, Kawasako T, Sasoaka I (1975) Extraneural metastasis of pineal tumor. Surg Neurol 3:49–54

    PubMed  CAS  Google Scholar 

  • Sandeman TF, Matthews JP (1979) The staging of testicular tumors. Cancer 43:2514–2524

    PubMed  CAS  Google Scholar 

  • Schold SC, Vugrin D, Golbey RB, Posner JB (1979) Central nervous system metastases from germ cell carcinoma of the testis. Semin Oncol 6:102–108

    PubMed  CAS  Google Scholar 

  • Scully RE (1979) Tumors of the Ovary and Maldeveloped Gonads. Armed Forces Institute of Pathology, Washington, pp 38–43

    Google Scholar 

  • Serov SF, Scully RE (1973) Histological Typing of Ovarian Tumors. World Health Organization, Geneva

    Google Scholar 

  • Sigel A, Krieger F (1977) Scrotal operation or biopsy of testicular tumors - a fatal mistake? Recent Results Cancer Res 60:212–214

    PubMed  Google Scholar 

  • Skakkebaek NE (1975) Atypical germ cells in the adjacent “normal” tissue of testicular tumours. Acta Pathol Microbiol Scand A 83:127–130

    PubMed  CAS  Google Scholar 

  • Skakkebaek NE, Berthelsen JG, Visfeldt J (1981) Clinical aspects of testicular carcinoma-in-situ. In: Skakkebaek NE, Berthelsen JG, Grigor KM, Visfeldt J (eds) Early Detection of Testicular Cancer. Scriptor, Copenhagen, pp 153–160

    Google Scholar 

  • Skinner DG (1976) Non-seminomatous testis tumors: A plan of management based on 96 patients to improve survival in all stages by combined therapeutic modalities. J Urol 115:65–69

    PubMed  CAS  Google Scholar 

  • Smith DR, Hardman JM, Earle KM (1969) Metastasizing neuroectodermal tumors of the central nervous system. J Neurosurg 31:50–58

    PubMed  CAS  Google Scholar 

  • Smithers DW (1969) Maturation in human tumours. Lancet 2:949–952

    PubMed  CAS  Google Scholar 

  • Snijder RN (1969) Completely mature pulmonary metastasis from testicular teratocarcinoma. Case report and review of literature. Cancer 24:810–819

    Google Scholar 

  • Solter D, Knowles BB (1978) Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Nat Acad Sci USA 75:5565–5569

    PubMed  CAS  Google Scholar 

  • Solter D, Damjanov I (1979) Teratocarcinoma and the expression of onco-developmental genes. Methods Cancer Res 18:277–332

    Google Scholar 

  • Solter D, Shevinsky L, Knowles BB, Strickland S (1979) The induction of antigenic changes in a teratocarcinoma stem cell line (F9) by retinoic acid. Dev Biol 70:515–521

    PubMed  CAS  Google Scholar 

  • Stoter G, Vendrik CPJ, Struyvenberg A, Brouwers ThM, Sleyfer DTh, Schraffordt Koops H, Van Oosterom AT, Pinedo HM (1979) Combination chemotherapy with Cis-diammine-dichloro-platinum, vinblastine and bleomycin in advanced testicular non-seminoma. Lancet 1:941–945

    PubMed  CAS  Google Scholar 

  • Sung DL, Harisiadis L, Chang CH (1978) Midline pineal tumors and suprasellar germinomas: highly curable by irradiation. Radiology 128:745–751

    PubMed  CAS  Google Scholar 

  • Takei Y, Pearl GS (1981) Ultrastructural study of intracranial yolk sac tumor: with special reference to the oncologic phylogeny of germ cell tumors. Cancer 48:2038–2046

    PubMed  CAS  Google Scholar 

  • Talerman A (1975) The incidence of yolk sac tumor (endodermal sinus tumor) elements in germ cell tumors of the testis in adults. Cancer 36:211–215

    PubMed  CAS  Google Scholar 

  • Thurlbeck WM, Scully RE (1960) Solid teratoma of the ovary. A clinicopathological analysis of 9 cases. Cancer 13:804–811

    PubMed  CAS  Google Scholar 

  • Vugrin D, Cvitkovic E, Whitmore WF, Golbey RB (1979a) Adjuvant chemotherapy in resected nonseminomatous germ cell tumors of the testis: stage I and II. Semin Oncol 6:94–98

    PubMed  CAS  Google Scholar 

  • Vugrin D, Cvitkovic E, Posner J, Hajdu S, Golbey RB (1979b) Neurological complications of malignant germ cell tumors of testis. Biology of brain metastases (I). Cancer 44:2349–2353

    PubMed  CAS  Google Scholar 

  • Vugrin D, Cvitkovic E, Whitmore WF, Cheng E, Golbey RB (1981a) VAB-4 combination chemotherapy in the treatment of metastatic testis tumors. Cancer 47:833–839

    PubMed  CAS  Google Scholar 

  • Vugrin D, Whitmore WF, Cvitkovic E, Grabstald H, Sogani P, Barzell W, Golbey RB (1981b) Adjuvant chemotherapy combination of Vinblastine, Actinomycin D, Bleomycin and Chlorambucil following retroperitoneal lymph node dissection for stage II testis tumor. Cancer 47:840–844

    PubMed  CAS  Google Scholar 

  • Vugrin D, Whitmore WF, Sogani PC, Bains M, Herr HW, Golbey RB (1981c) Combined chemotherapy and surgery in treatment of advanced germ-cell tumors. Cancer 47:2228–2231

    PubMed  CAS  Google Scholar 

  • Walter P (1980) Séminome spermatocytaire. Etude de 8 observations et revue de la littérature. Virchows Arch A 386:175–187

    CAS  Google Scholar 

  • Weiss L (1976) Introduction. In: Weiss L (ed) Fundamental Aspects of Metastasis. North Holland, Amsterdam, pp 1–6

    Google Scholar 

  • Weiss L (1980) Pathophysiology of metastasis within the lymphatic system. In: Weiss L, Gilbert HA, Ballon SC (eds) Lymphatic System Metastasis. Hall, Boston pp 2–40

    Google Scholar 

  • Whitmore WF (1970) Germinal tumors of the testis. In: National Cancer Conference 6th, Denver 1968, Proceedings. Lippincott, Philadelphia, pp 219–245

    Google Scholar 

  • Whitmore WF (1979) Surgical treatment of adult germinal testis tumors. Semin Oncol 6:55–68

    PubMed  Google Scholar 

  • Williams SD, Einhorn LH (1979) Brain metastases in disseminated germinal neoplasms. Incidence and clinical course. Cancer 44:1514–1516

    PubMed  CAS  Google Scholar 

  • Willis GW, Hajdu SI (1973) Histologically benign teratoid metastasis of testicular embryonal carcinoma. Am J Clin Path 59:338–343

    PubMed  CAS  Google Scholar 

  • Wilson ER, Takei Y, Bikoff WT, O’Brien MS, Tindall GT, Boehm WM (1979) Abdominal metastases of primary intracranial yolk sac tumors through ventriculoperitoneal shunts: Report of three cases. Neurosurgery 5:356–364

    PubMed  CAS  Google Scholar 

  • Wobbes Th, Schraffordt Koops H, Oldhoff J (1980) The relation between testicular tumours, undescended testes and inguinal hernias. J Surg Oncol 14:45–51

    PubMed  CAS  Google Scholar 

  • Wogalter H, Scofield GF (1962) Adult teratoma of the testicle metastasizing as adult teratoma. J Urol 87:573–576

    PubMed  CAS  Google Scholar 

  • Wolf A, Cowen D, Stewart WB (1954) Glioblastoma with extraneural metastases by way of ventriculopleural anastomosis. Trans Am Neurol Assoc 79:140–142

    Google Scholar 

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  1. Pathology Department of the University of Groningen, Groningen, The Netherlands

    Jan Wolter Oosterhuis

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  1. Jan Wolter Oosterhuis
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  1. Department of Pathology, Hahnemann Medical College and Hospital, Philadelphia, Pennsylvania, USA

    Ivan Damjanov

  2. The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA

    Davor Solter

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Oosterhuis, J.W. (1983). The Metastasis of Human Teratomas. In: Damjanov, I., Knowles, B.B., Solter, D. (eds) The Human Teratomas. Contemporary Biomedicine, vol 3. Humana Press. https://doi.org/10.1007/978-1-4612-5628-1_6

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  • DOI: https://doi.org/10.1007/978-1-4612-5628-1_6

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