Pancreas and Pineal

  • R. L. Hazelwood
  • D. C. Meyer

Abstract

The avian pancreas is located in the abdominal cavity of all birds on the right side; it is tightly bound by mesentery and blood vessels in position between the descending and ascending duodenal loops. This organ varies greatly in size, although it is always well formed and exhibits discrete characteristics. It varies in weight, from 2 to 4 g in 1.5–2.1 kg adult chickens to a mere fraction of a gram in most passerine species, whose body weight may be at the most a few grams. Generally, it has a smooth macroscopic appearance, is yellowish white in color, and does not exhibit the highly vascular appearance so common to other vertebrate endocrine glands such as thyroid and adrenal tissue, etc.

Keywords

Pineal Gland Pancreatic Polypeptide Japanese Quail Domestic Fowl Ventral Lobe 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

Pancreas

  1. Andrew, A. (1977). Pancreatic D cells in very young chick embryos. Gen. Comp. Endocrinol., 31, 463.PubMedCrossRefGoogle Scholar
  2. Beaupain, D., and F. Dieterlen-Lievre. (1974). Etude immunocytologique de la differ enciation du pancreas endocrine chez l’embryon de poulet. Gen. Comp. Endocrinol., 23, 421.PubMedCrossRefGoogle Scholar
  3. Benzo, C.A., and T.D. Green. (1974). Functional differentiation of the chick endocrine pancreas: insulin storage and secretion. Anat. Rec., 180, 491.PubMedCrossRefGoogle Scholar
  4. Benzo, C.A., and S.B. Stearns. (1975). Radioimmunological evidence for early functional activity in chick embryonic alpha cells. Am. J. Anat., 142, 515.PubMedCrossRefGoogle Scholar
  5. Cameron, D.P., W. Stauffacher, L. Orci, M. Amherdt, and A.E. Renold. (1972). Defective immunoreactive insulin secretion in Acomys cahirinus. Diabetes, 21, 1060.PubMedGoogle Scholar
  6. Cieslak, S.R. (1984). Master’s Thesis, University of Houston, Houston, Texas.Google Scholar
  7. Cieslak, S.R., and R.L. Hazelwood. (1983). Does somatostatin (SRIF) stimulate glucagon release in Aves? Endocrinology, 112, 398 (Abstr. 1271).Google Scholar
  8. Colca, J.R., and R.L. Hazelwood. (1976). Pancreatectomy in the chicken: does an extra-pancreatic source of insulin exist? Gen. Comp. Endocrinol., 28, 151.PubMedCrossRefGoogle Scholar
  9. Colca, J.R., and R.L. Hazelwood. (1982). Persistence of im-munoreactive insulin, glucagon and pancreatic polypeptide in the plasma of depancreatized chickens. J. Endocrinol. (London), 92, 317.Google Scholar
  10. Dahl, E. (1973). The fine structure of the pancreatic nerves of the domestic fowl. Z. Zellforsch. Mikrosk. Anat., 136, 501.PubMedCrossRefGoogle Scholar
  11. DePablo, F., J. Roth, E. Hernandez, and R.M. Pruss. (1982). Insulin is present in chicken eggs and early chick embryos. Endocrinology, 111, 1909.CrossRefGoogle Scholar
  12. Dieterlen-Lievre, F., and D. Beaupain. (1974). Etude immunocytologique de la différenciation du pancreas endocrine chez l’embryon de poulet. I. Ilots a insuline. Gen. Comp. Endocrinol., 22, 62.PubMedCrossRefGoogle Scholar
  13. Goldman, J., W. Pugh, A. Yuen, and J.R. Kimmel. (1978). Differentiation of the avian endocrine pancreas. Diabetes, 27, 478 (Abstr.).Google Scholar
  14. Hazelwood, R.L. (1976). In “Avian Physiology” (3rd ed.) (P.D. Sturkie, Ed.). New York: Springer-Verlag, Chapter 21.Google Scholar
  15. Hazelwood, R.L. (1981). In “The Islets of Langerhans” (S. Cooperstein and D. Watkins, Eds.). New York: Academic Press, Chapter 12.Google Scholar
  16. Hseih, T.M. (1951). The sympathetic and parasympathetic nervous system of the fowl. Ph.D. Thesis, Royal Veterinary College, Edinburgh.Google Scholar
  17. King, D.L. (1971). Possible parasympathetic control of insulin secretion from the endocrine pancreas of the domestic fowl. M.S. Thesis, University of Houston, Houston, Texas.Google Scholar
  18. Langslow, D.R., J.R. Kimmel, and H.G. Pollock. (1973). Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals. Endocrinology, 93, 558.PubMedCrossRefGoogle Scholar
  19. Leibson, L., V. Bondareva, and L. Soltitskaya. (1976). The secretion and role of insulin in chick embryos and chicks. In “The Evolution of Pancreatic Islets” ( T. Grillo, L. Leibson, and A. Epple, Eds.) New York: Academic Press, p. 69.Google Scholar
  20. Mikami, S., and K. Ono. (1962). Glucagon deficiency induced by extirpation of alpha islets of the fowl pancreas. Endocrinology, 71, 464.PubMedCrossRefGoogle Scholar
  21. Oakberg, E.F. (1949). Quantitative studies of pancreas and islands of Langerhans in relation to age, sex, and body weight in White Leghorn chickens. Am. J. Anat., 84, 279.PubMedCrossRefGoogle Scholar
  22. Pollock, H.G., and J.R. Kimmel. (1981). Immunoassay for avian pancreatic polypeptide and applications in chickens. Gen. Comp. Endocrinol., 45, 386.PubMedCrossRefGoogle Scholar
  23. Przbylski, R.J. (1967a). Cytodifferentiation of the chick pancreas II. Ultrastructure of the acinar cells. J. Morphol., 123, 85.CrossRefGoogle Scholar
  24. Przbylski, R.J. (1967b). Cytodifferentiation of the chick pancreas. I. Ultrastructure of the islet cells and the initiation of granule formation. Gen. Comp. Endocrinol., 8, 115.CrossRefGoogle Scholar
  25. Rawdon, B.B., and A. Andrew. (1979). An immunocytochemical study of the distribution of pancreatic endocrine cells in chicks with special reference to the relationship between pancreatic polypeptide and somatostatin-immunoreactive cells. Histochemistry, 59, 189.PubMedCrossRefGoogle Scholar
  26. Smith, P.H. (1973). Pancreatic islets of Coturnix quail: Special reference to the islet organ of the splenic lobe. Anat. Rec., 178, 567.CrossRefGoogle Scholar
  27. Spiess, J., J.E. Rivier, J.A. Rodkey, C.D. Bennett, and W. Vale. (1979). Isolation and characterization of somatostatin from pigeon pancreas. Proc. Natl. Acad. Sci. U.S.A., 76, 2974.PubMedCrossRefGoogle Scholar
  28. Stellenwerf, W.A., and R.L. Hazelwood. (1978). Peripheral utilization of a glucose load in rats and chickens after alloxan and streptozotocin: A comparison. Gen. Comp. Endocrinol., 39, 131.CrossRefGoogle Scholar
  29. Swenne, I., and G. Lundquist. (1980). Islet structure and pancreatic hormone content of the developing chick embryo. Gen. Comp. Endocrinol., 41, 190.PubMedCrossRefGoogle Scholar
  30. Trenkle, A., and K. Hopkins (1971). Immunological investigation of an insulin-like substance in the chicken egg. Gen. Comp. Endocrinol., 16, 493.PubMedCrossRefGoogle Scholar
  31. Watanabe, T., and M. Yasuda. (1977). Electron microscopic study on the innervation of the pancreas of the domestic fowl. Cell Tissue Res., 180, 453.PubMedCrossRefGoogle Scholar
  32. Weir, G.C., P.C. Goltsos, E.P. Steinberg, and Y.C. Patel. (1976). High concentration of somatostatin immunoreactivity in chicken pancreas. Diabetologia, 12, 129.PubMedCrossRefGoogle Scholar
  33. Woods, S.C., and D. Porte, Jr. (1974). Neural control of the endocrine pancreas. Physiol. Rev., 54, 596.PubMedGoogle Scholar

Pineal

  1. Balemans, M. (1972). Age-dependent effects of 5-methoxytryptophol and melatonin on testes and comb growth of the White Leghorn (Gallus domesticus L.). J. Neural Transm., 33, 179.PubMedCrossRefGoogle Scholar
  2. Balemans, M. (1973). The inhibitory effect of 5-methoxytryptophol on ovarian weight, follicular growth, and egg production of adult White Leghorn hens (Gallus domesticus L.). J. Neural Trans., 34, 159.CrossRefGoogle Scholar
  3. Barchas J., F. DaCosta, and S. Spector. (1967). Acute pharmacology of melatonin. Nature (London), 214, 919.CrossRefGoogle Scholar
  4. Binkley, S., E. Kluth, and M. Menaker. (1971). Pineal function in sparrows: circadian rhythms and body temperature. Science, 174, 311.PubMedCrossRefGoogle Scholar
  5. Binkley, S., S. MacBride, D. Klein, and C. Ralph. (1973). Pineal enzymes: regulation of avian melatonin synthesis. Science, 181, 273.CrossRefGoogle Scholar
  6. Binkley-Tatem, S. (1984). Dark and light pulses shift circadian rhythms. Satellite Symposium; 7th International Congress of Endocrinology, Abstr. H 100. J. Steroid Biochem., 20, 6B.Google Scholar
  7. Cardinali, D.P., A.E. Cuello, J. Tramezzani, and J.M. Rosner. (1971). Effects of pinealectomy on the testicular function of the adult male duck. Endocrinology, 89, 1082.PubMedCrossRefGoogle Scholar
  8. Cogburn, L.A., and P.C. Harrison. (1980). Adrenal, thyroid, and rectal temperature responses of pinealectomized cockerels to different ambient temperatures. Poult. Sci., 59 (5), 1132.PubMedGoogle Scholar
  9. Deguchi, T. (1979). A circadian oscillator in cultured cells of chicken pineal gland. Nature (London), 282, 94.CrossRefGoogle Scholar
  10. Deguchi, T. (1981). Rhodopsin-like photosensitivity of isolated chicken pineal gland. Nature (London), 290 (5808), 706.CrossRefGoogle Scholar
  11. Gaston, S., and M. Menaker. (1968). Pineal function: the biological clock in sparrow. Science, 160, 1125.PubMedCrossRefGoogle Scholar
  12. Grady, R.K., Jr., A. Caliguri, and I. V. Mefford. (1984). Day/night differences in pineal indoles in the adult pigeon. Comp. Biochem. Physiol., C: Comp. Pharmacol., 78, 141.CrossRefGoogle Scholar
  13. Gwinner, E., and I. Benzinger. (1978). Synchronization of a circadian rhythm in pinealectomized European starlings by daily injections of melatonin. J. Comp. Physiol., A, 127 (3), 209.CrossRefGoogle Scholar
  14. Harrison, P.C., and W.C. Becker. (1969). Extraretinal photocontrol of oviposition in pinealectomized domestic fowl. Proc. Soc. Exp. Biol. Med., 132, 164.Google Scholar
  15. Harrison, P.C., C.J. Organek, and L. Cogburn. (1974). Northeastern Regional report (NE-61).Google Scholar
  16. Hedlund, L., and C.L. Ralph. (1967). Daily variation of pineal serotonin in Japanese quail and Sprague-Dawley rats. Am. Zool., 7, 712.Google Scholar
  17. Hedlund, L., and A.V. Nalbandov. (1969). Innervation of the avian pineal body. Am. Zool., 9, 1090.Google Scholar
  18. Hedlund, L., C.L. Ralph, J.D. Chepko, and J.J. Lynch. (1971). A diurnal serotonin cycle in the pineal body of Japanese quail: Photoperiod phasing and the effect of superior cervical ganglionectomy. Gen. Comp. Endocrinol., 16, 52.PubMedCrossRefGoogle Scholar
  19. Homma, K., L. McFarland, and W.O. Wilson (1967). Response of the reproductive organs of the Japanese Quail to pinealectomy and melatonin injections. Poult. Sci., 46, 314.Google Scholar
  20. Injidi, M.H., and J.M. Forbes. (1983). Growth and food intake of intact and pinealectomized chickens treated with melatonin and triiodothyronine. Br. Poult. Sci., 24, 463.PubMedCrossRefGoogle Scholar
  21. Lynch, H.J. (1971). Diurnal oscillations in pineal melatonin content. Life Sci., 10, 791.CrossRefGoogle Scholar
  22. MacBride, S.E., C.L. Ralph, S. Binkley, and D.C. Klein. (1973). Pineal rhythms persist in superior cervical ganglioectomized chickens. Fed. Proc. Fed. Am. Soc. Exp. Biol., 32, 251 (Abstr.).Google Scholar
  23. Maria, G., P. de Gallardo, and R.S. Piezzi. (1973). Serotonin content in pineal gland of Antarctic penguin. Gen. Comp. Endocrinol., 21, 468.CrossRefGoogle Scholar
  24. Meyer, D.C., P.D. Sturkie, and K. Gross. (1973). Diurnal rhythm in serotonin of blood and pineals of chickens. Comp. Biochem. Physiol. A, 46, 619.PubMedCrossRefGoogle Scholar
  25. Moore, Y.S., A. Heller, R. Bhatnager, R. Wurtman, and J. Axelrod. (1968). Central control of the pineal gland: Visual pathways. Arch. Neurol., 18, 208.PubMedGoogle Scholar
  26. Moszowska, A., A. Scemama, M.M. Lombard, and M. Hery. (1973). Experimental modulation of hypothalamic content of the gonadotropic releasing factors by pineal factors in the rat. J. Neural Transm., 34, 11.CrossRefGoogle Scholar
  27. Pelham, R.W., and C.L. Ralph (1973). Diurnal rhythm of serum melatonin in chicken: abolition by pinealectomy. Physiologist, 16, 236.Google Scholar
  28. Quay, W.B. (1963). Circadian rhythm in rat pineal serotonin and its modifications by estrous cycle and photoperiod. Gen. Comp. Endocrinol., 3, 473.CrossRefGoogle Scholar
  29. Quay, W.B. (1964). Circadian and estrus rhythms in pineal melatonin and 5-hydroxyindole-3-acetic acid (5-HIAA). Proc. Soc. Exp. Biol. Med., 115, 710.PubMedGoogle Scholar
  30. Quay, W.B. (1966). Rhythmic and light-induced changes in levels of pineal 5-hydroxyindoles in the pigeon (Columba livia). Gen Comp. Endocrinol., 6, 371.PubMedCrossRefGoogle Scholar
  31. Quay, W.B. (1974). “Pineal Chemistry.” Springfield: Thomas.Google Scholar
  32. Ralph, C.L., L. Hedlund, and W.A. Murphy. (1967). Diurnal cycles of melatonin in bird pineal bodies. Comp. Biochem. Physiol., 22, 591.CrossRefGoogle Scholar
  33. Reiter, R.J. (1973). Comparative physiology: Pineal gland. Annu. Rev. Physiol., 35, 305.PubMedCrossRefGoogle Scholar
  34. Saylor, A., and A. Wolfson. (1967). Avian pineal gland: progonadotrophic response in the Japanese quail. Science, 158, 1478.CrossRefGoogle Scholar
  35. Shellabarger, C.J. (1953). Observations on the pineal in the White Leghorn capon and cockerel. Poult. Sci., 32, 189.Google Scholar
  36. Singh, D.V., and C.W. Turner. (1967). Effect of melatonin upon the thyroid hormone secretion rate and endocrine glands of chicks. Proc. Soc. Exp. Biol. Med., 125, 407.PubMedGoogle Scholar
  37. Sharp, P.J., K. Klandorf, and R.W. Lea. (1984). Influence of lighting cycles on daily rhythms in concentrations of plasma tri-iodotyronine and thyroxine in intact and pinealectomized immature broiler hens (Gallus-domesticus). J. Endocrinol., 103, 337–345.PubMedCrossRefGoogle Scholar
  38. Sturkie, P.D., J.J. Woods, and D. Meyer. (1972). Serotonin levels in blood, heart, and spleen of chickens, ducks and pigeons. Proc. Soc. Exp. Biol. Med., 139, 364.PubMedGoogle Scholar
  39. Takahashi, J.S., H. Hamm, and M. Menaker. (1980). Orcadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro. Proc. Natl. Acad. Sci. U.S.A., 77 (4), 2319.PubMedCrossRefGoogle Scholar
  40. Tanabe, Y., K. Nakamura, and T. Nakamura. (1984). Photoperiodic regulation of plasma melatonin in intact or pinealectomized chickens. Satellite Symposium, 7th International Congress of Endocrinology, Abstr. H99. J. Steroid Biochem., 20, 6B.CrossRefGoogle Scholar
  41. Wight, P.A.L., and G.M. MacKenzie. (1971). The histochemistry of the pineal gland of the domestic fowl. J. Anat., 108, 261.PubMedGoogle Scholar
  42. Wurtman, R.J., J. Axelrod, and D. Kelly. (1968). “The Pineal.” New York: Academic Press.Google Scholar
  43. Zimmerman, N.H., and M. Menaker. (1975). Neural connections of sparrow pineal: role in circadian control of activity. Science, 190 (4213), 477.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York, Inc. 1986

Authors and Affiliations

  • R. L. Hazelwood
  • D. C. Meyer

There are no affiliations available

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