Infectious Diseases Associated with Escherichia Coli

  • Lee W. Riley
Chapter

Abstract

Escherichia coli first described by Theodore Escherich in 1885, was initially regarded as a nonpathogenic commensal present in feces. Over time, however, the pathogenic potential of some E. coli strains became recognized and today, diseases associated with E. coli span a wide spectrum of clinical manifestations, epidemiologic patterns, pathogenesis, diagnostic considerations, and management. Hence, each disease associated with E. coli must be addressed separately.

Keywords

Urinary Tract Infection Virulence Determinant Asymptomatic Bacteriuria Neonatal Meningitis Colonization Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Literature Cited

  1. Agbonlahor, D. E., and T. O. Odugbemi. 1982. Enteropathogenic, enterotoxigenic, and enteroinvasive Escherichia coli isolated from acute gastroenteritis patients in Lagos, Nigeria. Trans. R. S. Trop. Med. Hyg. 76:265–67.Google Scholar
  2. Arnow, P. M., L. M. Weiss, D. Weil, and N. R. Rosen. 1986. Escherichia coli sepsis from contaminated platelet transfusion. Arch. Intern. Med. 146:321–324.PubMedGoogle Scholar
  3. Baumgartner, J-D.,M. P. Glauser, J. A. McCutchan, E. J. Ziegler, G. van Melle, M. R. Klauber, M. Vogt, E. Muehlen, R. Luethy, R. Chiolero, and S. Geroulanos. 1985. Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid. Lancet ii:59–63.Google Scholar
  4. Bennet, R., M. Eriksson, B. Melen, and R. Zetterstrom. 1985. Changes in the incidence and spectrum of neonatal septicemia during a fifteen-year period. Acta Paediatr. Scand. 74:687–690.PubMedGoogle Scholar
  5. Beutler, B., and A. Cerami. 1987. Cachectin: More than a tumor necrosis factor. N. Engl. J. Med. 316:379–385.PubMedGoogle Scholar
  6. Black, R. E., K. H. Brown, and S. Becker. 1984. Effects of diarrhea associated with specific enteropathogens on the growth of children in rural Bangladesh. Pediatrics 6:799–805.Google Scholar
  7. Bodey, G. P., L. Elting, H. Kassamali, and B. Lim. 1986. Escherichia coli bacteremia in cancer patients. Am. J. Med. 81:85–95.PubMedGoogle Scholar
  8. Boileau, C. R., H. M. D’Hauteville, and P. J. Sansonetti. 1984. DNA hybridization technique to detect Shigella species and enteroinvasive Escherichia coli. J. Clin. Microbiol. 20:959–961.PubMedGoogle Scholar
  9. Bone, R. C., C. J. Fisher, T. P. Clemmer, G. J. Slotman, C. A. Metz, R. A. Balk, and the Methylprednisolone Severe Sepsis Study Group. 1987. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N. Engl. J. Med. 317:653–658.PubMedGoogle Scholar
  10. Bopp, C. A., K. D. Greene, F. P. Downes, E. G. Sowers, J. G. Wells, and I. K. Wachsmuth. 1987. Unusual verotoxin-producing Escherichia coli associated with hemorrhagic colitis. J. Clin. Microbiol. 25:1486–1489.PubMedGoogle Scholar
  11. Bray, J. 1945. Isolation of antigenically homogeneous strains of Bact. coli neopolitanum from summer diarrhoea of infants. J. Pathol. Bacteriol. 57:239–247.Google Scholar
  12. Carter, A. O., A. A. Borczyk, J. A. K. Carlson, B. Harvey, J. C. Hockin, M. A. Karmali, C. Krishnan, D. A. Korn, and H. Lior. 1987. A severe outbreak of Escherichia coli 0157:H7-associated hemorrhagic colitis in a nursing home. N. Engl. J. Med. 317:1496–1500.PubMedGoogle Scholar
  13. Centers for Disease Control. 1986. Surveillance summaries 1986. 35:17ss–29ss.Google Scholar
  14. Cravioto, A., R. J. Gross, S. M. Scotland, and B. Rowe. 1979. An adhesive factor found in strains of Escherichia coli belonging to the traditional infantile enteropathogenic serotypes. Curr. Microbiol. 3:95–99.Google Scholar
  15. Damato, J. J., M. T. Collins, M. V. Rothlauf, and J. K. McClatchy. 1983. Detection of mycobacteria by radio-metric and standard plate procedures. J. Clin. Microbiol. 17:1066–1073.PubMedGoogle Scholar
  16. D’Amato, R. F., J. C. McLaughlin, and M. J. Ferraro. 1985. Rapid and mechanized/automated methods for the detection and identification of bacteria and yeasts, p. 52–65. In: E. H. Lennette, A. Balows, W. J. Hausler Jr., and H. J. Shadomy (ed.). Manual of clinical microbiology. American Society for Microbiology, Washington, D.C.Google Scholar
  17. Day, N. P., S. M. Scotland, and B. Rowe. 1981. Comparison of an HEp-2 tissue culture test with the Sereny test for detection of enteroinvasiveness in Shigella spp. and Escherichia coli. J. Clin. Microbiol. 13:596–597.PubMedGoogle Scholar
  18. Dean, A. G., Y. C. Ching, R. G. Williams, and L. B. Harden. 1972. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J. Infect. Dis. 125:407–411.PubMedGoogle Scholar
  19. Dietzman, D. E., G. W. Fischer, and F. D. Schoenknecht. 1974. Neonatal Escherichia coli septicemia—bacterial counts in blood. J. Pediatr. 85:128–130.PubMedGoogle Scholar
  20. Donta, S. T., H. W. Moon, and S. C. Whipp. 1974. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture. Science 183:334–336.PubMedGoogle Scholar
  21. Donta, S. T., R. B. Wallace, S. C. Whipp, and J. Olarte. 1977. Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J. Infect. Dis. 135:482–485.PubMedGoogle Scholar
  22. DuPont, H. L., and W. W. Spink. 1969. Infections due to gram-negative organisms: an analysis of 860 patients with bacteremia at the University of Minnesota Medical Center, 1958–1966. Medicine 48:307–332.PubMedGoogle Scholar
  23. Echeverria, P., N. R. Blacklow, J. L. Vollet, C. V. Ulyangco, G. Cukor, V. B. Soriano, H. C. Dupont, J. H. Cross, F. Ørskov, and I. Ørskov. 1978. Reoviruslike agent and enterotoxigenic Escherichia coli infections in paediatric diarrhea in the Philippines. J. Infect. Dis. 138:326–332.PubMedGoogle Scholar
  24. Edwards, P. R., and W. H. Ewing. 1972. Identification of enterobacteriaceae, 3rd ed. Burgess Publishing Co., Minneapolis, Minnesota.Google Scholar
  25. European Organization for Research and Treatment of Cancer (EORTC). International Antimicrobial Therapy Cooperative Group. 1987. Ceftazidime combined with a short or long course of amikacin for empirical therapy of gram-negative bacteremia in cancer patients with granulocytopenia. N. Engl. J. Med. 317:1692–1698.Google Scholar
  26. Evans, D. G., and D. J. Evans Jr. 1978. New surface-associated heat-labile colonization factor antigen (CFA/II) produced by enterotoxigenic Escherichia coli of serogroups 06 and 08. Infect. Immun. 21:638–647.PubMedGoogle Scholar
  27. Evans, D. G., D. J. Evans Jr, W. S. Tjoa, and H. L. DuPont. 1978. Detection and characterization of colonization factor of enterotoxigenic Escherichia coli isolated from adults with diarrhea. Infect. Immun. 19:727–736.PubMedGoogle Scholar
  28. Evans, D. G., R. P. Silver, D. J. Evans Jr., D. G. Chase, and S. L. Gorbach. 1975. Plasmid-controlled colonization factor associated with virulence in Escherichia coli enterotoxigenic for humans. Infect. Immun. 12:656–667.PubMedGoogle Scholar
  29. Ewing, W. H., B. R. Davis, and T. S. Montague. 1963. Studies on the occurrence of Escherichia coli serotypes associated with diarrheal disease. Atlanta, Ga, U.S. Department of Health Service, Communicable Disease Center.Google Scholar
  30. Fairley, K. F., A. A. G. Bond, A. B. Brown, and P. Habersberger. 1967. Simple test to determine the site of urinary tract infections. Lancet ii:7513–7514.Google Scholar
  31. Farmer, J. J., III, B. R. Davis, F. W. Hickman-Brenner, A. McWhorter, G. P. Huntley-Carter, M. A. Asbury, C. Riddle, H. G. Wathen-Grady, C. Elias, G. R. Fanning, A. G. Steigerwalt, C. M. O’Hara, G. K. Morris, P. B. Smith, and D. J. Brenner. 1985. Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens. J. Clin. Microbiol. 21:46–76.PubMedGoogle Scholar
  32. Field, M. 1979. Modes of action of enterotoxins from Vibrio cholerae and Escherichia coli. Rev. Infect. Dis. 1:918–925.PubMedGoogle Scholar
  33. Finne, J., M. Leinonen, P. H. Makela. 1983. Antigenic similarities between brain components and bacteria causing meningitis. Lancet ii:354–357.Google Scholar
  34. Fitzhardinge, P. M., M. Kazemi, M. Ramsay, and L. Stern. 1974. Long-term sequelae of neonatal meningitis. Dev. Med. Child. Neurol. 16:3–10.PubMedGoogle Scholar
  35. Florman, A. L. and D. Teubner. 1969. Enhancement of bacterial growth in amniotic fluid by meconium. J. Pediatr. 74:111–114.PubMedGoogle Scholar
  36. Francis, D. H., J. E. Collins, and J. R. Duimstra. 1986. Infection of gnotobiotic pigs with an Escherichia coli 0157:H7 strain associated with an outbreak of hemor-rhagic colitis. Infect. Immun. 51:953–956.PubMedGoogle Scholar
  37. Freedman, R. M., D. L. Ingram, I. Gross, R. A. Ehrenkranz, J. B. Warshaw, and R. S. Baltimore. 1981. A half century of neonatal sepsis at Yale. Am. J. Dis. Child. 135:140–144.PubMedGoogle Scholar
  38. Gariepy, J., and G. K. Schoolnik. 1986. Design of a photoreactive analogue of the Escherichia coli heat-stable enterotoxin STIb: use in identifying its receptor on rat brush border membranes. Proc. Natl. Acad. Sci. USA 83:483–487.PubMedGoogle Scholar
  39. Gasser, C., E. Gautier, A. Stgech, R. E. Siebenmann, and R. Dechslin. 1955. Hamolytischuramische syndrome: Bilatorale Nierenrindennekrosen bei akuten erworbenen hamolytischen Anamien. Schweiz. Med. Wschr. 85:905–909.PubMedGoogle Scholar
  40. Giles, C., G. Sangster, and J. Smith. 1949. Epidemic gastroenteritis of infants in Aberdeen during 1947. Arch. Dis. Child. 24:45–53.PubMedGoogle Scholar
  41. Gillenwater, J. Y., R. B. Harrison, and C. N. Kunin. 1979. Natural history of bacteriuria in schoolgirls. N. Engl. J. Med. 301:396–399.PubMedGoogle Scholar
  42. Ginsburg, C. M., and G. H. McCracken. 1982. Urinary tract infections in young infants. Pediatrics 69:409–412.PubMedGoogle Scholar
  43. Glynn, A. A., and C. J. Howard. 1970. The sensitivity to complement of strains of Escherichia coli related to their K antigens. Immunology 18:331–346.PubMedGoogle Scholar
  44. Gomes, T. A., M. R. F. Toledo, L. R. Trabulsi, P. K. Wood, and J. G. Morris Jr. 1987. DNA probes for identification of enteroinvasive Escherichia coli. J. Clin. Microbiol. 25:2025–2027.PubMedGoogle Scholar
  45. Gorbach, S. L., B. H. Kean, D. G. Evans, D. J. Evans, and D. Bessudo. 1975. Travelers’ diarrhea and toxigenic Escherichia coli. N. Engl. J. Med. 292:933–936.PubMedGoogle Scholar
  46. Guerrant, R. L., L. V. Kirchhoff, D. S. Shields, M. K. Nations, J. Leslie, M. A. de Sousa, J. G. Araujo, L. L. Correia, K. T. Sauer, K. E. McClelland, F. L. Trowbridge, and J. M. Hughes. 1983. Prospective study of diarrheal illnesses in Northeastern Brazil: patterns of disease, nutritional impact, etiologies, and risk factors. J. Infect. Dis. 148:986–997.Google Scholar
  47. Gurwith, M. J., and T. W. Williams. 1977. Gastroenteritis in children: a two-year review in Manitoba. I. Etiology. J. Infect. Dis. 136:239–247.Google Scholar
  48. Harris, J. R., I. K. Wachsmuth, B. R. Davis, and M. L. Cohen. 1982. High molecular weight plasmid correlates with Escherichia coli enteroinvasiveness. Infect. Immun. 37:1295–1298.PubMedGoogle Scholar
  49. Honda, T., S. Taga, Y. Takeda, and T. Miwatani. 1981. Modified Elek test for detection of heat-labile enterotoxin of enterotoxigenic Escherichia coli. J. Clin. Microbiol. 13:1–5.PubMedGoogle Scholar
  50. Joe, L. K., B. Rukmono, S. Oemijati, K. Sahab, K. W. Newell, S. T. Hway, and R. W. Talogo. 1966. Diarrhoea among infants in a crowded area of Djakarta, Indonesia. Bull. Wld. Hlth. Org. 34:197–210.Google Scholar
  51. Jones, S. R., J. W. Smith, and J. P. Sanford. 1979. Localization of urinary tract infections by detection of anti- body-coated bacteria in urine sediment.- N. Engl. J. Med. 290:591–593.Google Scholar
  52. Källenius, G., R. Mollby, S. B. Svenson, J. Winberg, and H. Hultberg. 1980. Identification of a carbohydrate receptor recognized by uropathogenic Escherichia coli. Infection Suppl. 3:S288–S293.Google Scholar
  53. Karch, H., J. Heesemann, R. Laufs, A. D. O’Brien, C. O. Tacket, and M. M. Levine. 1987. A plasmid of enterohemorrhagic Escherichia coli 0157:H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells. Infect. Immun. 55:455–461.PubMedGoogle Scholar
  54. Karmali, M. A., B. T. Steele, M. Petric, and C. Lim. 1983. Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools. Lancet i:619–620.Google Scholar
  55. Kass, E. H. 1956. Asymptomatic infections of the urinary tract. Trans. Assoc. Am. Phys. 69:56–63.PubMedGoogle Scholar
  56. Kauffman, F. 1947. The serology of the coli group. J. Immunol. 57:71–100.Google Scholar
  57. Kim, K. S. 1985. Comparison of cefotaxime, imipenem-cilastatin, ampicillin-gentamicin, and ampicillin-chloramphenicol in the treatment of experimental Escherichia coli bacteremia and meningitis. Antimicrob. Agents Chemother. 28:433–436.PubMedGoogle Scholar
  58. Klein, J. O., and S. M. Marcy. 1976. Bacterial infections, p. 747–802. In: J. S. Remington, and J. O. Klein (ed), Infectious diseases of the fetus and newborn infant. W. B. Saunders Co., Philadelphia.Google Scholar
  59. Kunin, C. M. 1984. Genitourinary infections in the patient at risk: Extrinsic risk factors. Am. J. Med. 76(suppl): 131–139.PubMedGoogle Scholar
  60. Kunin, C. M. 1987. Detection, prevention, and management of urinary tract infections. Lea & Febiger, Philadelphia. 447 p.Google Scholar
  61. LaGamma, E. F., L. M. Drusin, A. W. Mackles, S. Machalek, and P. A. M. Auld. 1983. Neonatal infections. Am. J. Dis. Child. 137:838–841.Google Scholar
  62. Leffler, H., and C. Svanborg Eden. 1981. Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary epithelial cells and agglutinating human erythrocytes. FEMS Microbiol. Lett. 8:127–134.Google Scholar
  63. Levine, M. M. 1987. Escherichia coli that cause diarrhea: Enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent. J. Infect. Dis. 155:377–389.PubMedGoogle Scholar
  64. Levine, M. M., E. J. Bergquist, D. R. Nalin, D. H., Waterman, R. B. Hornick, C. R. Young, S. Sotman, and B. Rowe. 1978. Escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive. Lancet i: 1119–1122.Google Scholar
  65. Levine, M. M., J. P. Nataro, H. Karch, M. M. Baldini, J. B. Kaper, R. E. Black, M. L. Clements, and A. D. O’Brien. 1985. The diarrheal response of man to some classical enteropathogenic Escherichia coli is dependent upon a plasmid encoding an enteroadhesiveness factor. J. Infect. Dis. 152:550–559.PubMedGoogle Scholar
  66. Lindberg, U., U. Jodal, L. A. Hanson, and B. Kaijser. 1975. Asymptomatic bacteriuria in schoolgirls. IV. Difficulties of level diagnosis and the possible relation to the character of infecting bacteria. Acta Paediatr. Scand. 64:574–580.Google Scholar
  67. Lockwood, D. E., and D. C. Robertson. 1984. Development of a competitive enzyme-linked immunosorbent assay (ELISA) for Escherichia coli heat-stable enterotoxin (STa). J. Immunol. Methods 75:295–307.PubMedGoogle Scholar
  68. Lomberg, H., L. Å. Hanson, B. Jacobsson, U. Jodal, H. Leffler, and C. Svanborg Edén. 1983. Correlation of P blood group, vesicoureteral reflux, and bacterial attachment in patients with recurrent pyelonephritis. N. Engl. J. Med. 308:1189–1192.PubMedGoogle Scholar
  69. Marques, L. R. M., M. A. Moore, J. G. Wells, I. K. Wachsmuth, and A. D. O’Brien. 1986. Production of Shiga-like toxin by Escherichia coli. J. Infect. Dis. 154:338–341.PubMedGoogle Scholar
  70. Martin, M. L., L. D. Shipman, J. G. Wells, M. E. Potter, and K. Hedberg. 1986. Isolation of Escherichia coli 0157:H7 from dairy cattle associated with two cases of haemolytic-uremic syndrome. Lancet ii: 1043.Google Scholar
  71. Mathewson, J. J., P. C. Johnson, H. L. DuPont, D. R. Morgan, S. A. Thornton, L. V. Wood, and C. D. Ericsson. 1985. A newly recognized cause of travelers’ diarrhea: enteroadherent Escherichia coli. J. Infect. Dis. 151:471–475.PubMedGoogle Scholar
  72. McCabe, W. R., P. C. Carling, S. Bruins, and A. Greely. 1975a. The relation of K antigen to virulence of Escherichia coli. J. Infect. Dis. 131:6–10.PubMedGoogle Scholar
  73. McCabe, W. R., B. Kaijser, J. Ollings, M. Uwaydah, and L. A. Hanson. 1978. Escherichia coli in bacteremia: K and O antigens and serum sensitivity of strains from adults and neonates. J. Infect. Dis. 138:33–41.PubMedGoogle Scholar
  74. McCabe, W. R., S. M. Wolff, and J. V. Bennett. 1975b. Incidence of gram-negative bacteremia. N. Engl. J. Med. 292:111.Google Scholar
  75. McConnell, M. M., L. V. Thomas, N. P. Day, and B. Rowe. 1985. Enzyme-linked immunosorbent assays for the detection of adhesion factor antigens of enterotoxigenic Escherichia coli. J. Infect. Dis. 152:1120–1127.PubMedGoogle Scholar
  76. McCracken, G. H. Jr. 1984. Management of neonatal meningitis, 1984. J. Antimicrob. Chemother. Suppl. B 14:23–31.Google Scholar
  77. McCracken, G. H. Jr., and S. G. Mize. 1976. A controlled study of intrathecal antibiotic therapy in gram-negative enteric meningitis in infancy. J. Pediatr. 89:66–72.PubMedGoogle Scholar
  78. McCracken, G. H. Jr., S. G. Mize, and N. Threlkeld. 1980. Intra-ventricular gentamicin therapy in gram-negative bacillary meningitis of infancy. Report of the Second Neonatal Meningitis Cooperative Study Group. Lancet i:787–791.Google Scholar
  79. McCracken, G. H. Jr., L. D. Sarff, M. P. Glode, S. G. Mize, M. S. Schiffer, J. B. Robbins, E. C. Gotchlich, I. Orskov, and F. Orskov. 1974. Relation between Escherichia coli K1 capsular polysaccharide antigen and clinical outcome in neonatal meningitis. Lancet ii:246–250.Google Scholar
  80. McCracken, G. H. Jr., N. Threlkeld, S. G. Mize, C. J. Baker, S. L. Kaplan, I. Faingezicht, W. E. Feldman, U. Schaad, and the Neonatal Meningitis Cooperative Study Group. 1984. Moxalactam therapy for neonatal meningitis due to gram-negative bacilli. J. Am. Med. Assoc. 252:1427–1432.Google Scholar
  81. McGrady, G. A., J. R. Daling, and D. R. Peterson. 1985. Maternal urinary tract infection and adverse fetal outcomes. Am. J. Epidemiol. 121:377–381.PubMedGoogle Scholar
  82. McKay, D. G., and G. H. Wahle. 1955. Epidemic gastroenteritis due to Escherichia coli 0111:B4. Arch. Pathol. 60:679–693.Google Scholar
  83. Merson, M. H., F. Ørskov, I. Ørskov, R. B. Sack, I. Huq, and F. T. Koster. 1979. Relationship between enterotoxin production and serotypes in enterotoxigenic Escherichia coli. Infect. Immun. 23:325–329.PubMedGoogle Scholar
  84. Merson, M. H., G. K. Morris, D. A. Sack, J. G. Wells, J. C. Feeley, R. B. Sack, W. B. Creech, A. Z. Kapikian, and E. J. Gangarosa. 1976. Travelers’ diarrhea in Mexico. N. Engl. J. Med. 294:1299–1305.PubMedGoogle Scholar
  85. Morrison, D. M., D. L. J. Tyrrell, and L. D. Jewel. 1985. Colonic biopsy in verotoxin-induced hemorrhagic colitis and thrombotic thrombocytopenic purpura (TTP). Am. J. Clin. Pathol. 86:108–112.Google Scholar
  86. Moseley, S. L., P. Echeverria, J. Seriwatana, C. Tiparat, W. Chaicumpa, T. Sakuldaipeara, and S. Falkow. 1982. Identification of enterotoxigenic Escherichia coli by colony hybridization using three enterotoxin gene probes. J. Infect. Dis. 145:863–869.PubMedGoogle Scholar
  87. Moseley, S. L., I. Huq, A. R. M. A. Alim, M. So, M. Samadpour-Motalebi, and S. Falkow. 1980. Detection of enterotoxigenic Escherichia coli by DNA hybridization. J. Infect. Dis. 142:8792–8798.Google Scholar
  88. Mulder, C. J. J., L. van Alphen, and H. C. Zanen. 1984. Neonatal meningitis caused by Escherichia coli in the Netherlands. J. Infect. 9:177–184.PubMedGoogle Scholar
  89. Nataro, J. P., M. M. Baldini, J. P. Kaper, R. E. Black, N. Bravo, and M. M. Levine. 1985. Detection of an adherence factor in enteropathogenic Escherichia coli with a DNA probe. J. Infect. Dis. 152:560–565.PubMedGoogle Scholar
  90. Nataro, J. P., J. B. Kaper, R. Robins-Browne, V. Prado, P. Vial, and M. M. Levine. 1987. Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells. Pediatr. Infect. Dis. J. 6:829–831.PubMedGoogle Scholar
  91. Neubauer, M., E. Aldova, and J. Duben. 1982. Outbreak of enterocolitis caused by an enteroinvasive E. coli. Zbl. Bakt. Hyg. 252:507–513.Google Scholar
  92. O’Brien, A. D., and R. K. Holmes. 1987. Shiga and shiga-like toxins. Microbiol. Rev. 51:206–220.PubMedGoogle Scholar
  93. O’Brien, A. D., J. W. Newland, S. F. Miller, R. K. Holmes, H. W. Smith, and S. B. Formal. 1984. Shiga-like toxin-converting phases from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science 226:694–696.PubMedGoogle Scholar
  94. O’Hanley, P., D. Lark, S. Falkow, and G. K. Schoolnik. 1985. Molecular basis of Escherichia coli colonization of the upper urinary tract in BALB/c mice: gal-gal pili immunization prevents E. coli pyelonephritis. J. Clin. In¬vest. 75:347–360.Google Scholar
  95. Ørskov, I., A. Ferencz, and F. Ørskov. 1980. Tamm-Horsfall protein or uromucoid is the normal urinary slime that traps type 1 fimbriated Escherichia coli. Lancet i:887.Google Scholar
  96. Ørskov, I., and F. Ørskov. 1985. Escherichia coli in extraintestinal infections. J. Hyg. Camb. 95:551–575.PubMedGoogle Scholar
  97. Ørskov, I., F. Ørskov, B. Jann, and K. Jann. 1977. Serology, chemistry, and genetics of O and K antigens of Escherichia coli. Bacteriol. Rev. 41:667–710.PubMedGoogle Scholar
  98. Pai, C. H., R. Gordon, H. V. Sims, and L. E. Bryan. 1984. Sporadic cases of hemorrhagic colitis associated with Escherichia coli O157:H7. Ann. Intern. Med. 101:738–742.PubMedGoogle Scholar
  99. Pal, T., A. S. Pacsa, L. Emody, S. Voros, and E. Selley. 1985. Modified enzyme-linked immunosorbent assay for detecting enteroinvasive Escherichia coli and virulent Shigella strains. J. Clin. Microbiol. 21:415–418.PubMedGoogle Scholar
  100. Paulozzi, L. J., K. E. Johnson, L. M. Kamahele, C. R. Clausen, L. W. Riley, and S. D. Helgerson. 1986. Diarrhea associated with adherent enteropathogenic Escherichia coli in an infant and toddler center, Seattle, Washington. Pediatrics 77:296–300.PubMedGoogle Scholar
  101. Quie, P. G. 1987. The white cells: Use of granulocyte transfusions. Rev. Infect. Dis. 9:189–193.PubMedGoogle Scholar
  102. Remis, R. S., K. L. MacDonald, L. W. Riley, N. D. Puhr, J. G. Wells, B. R. Davis, P. A. Blake, and M. L. Cohen. 1984. Sporadic cases of hemorrhagic colitis associated with Escherichia coli 0157:H7. Ann. Intern. Med. 101:624–626.PubMedGoogle Scholar
  103. Riley, L. W. 1987. The epidemiologic, clinical, and microbiologic features of hemorrhagic colitis. Ann. Rev. Microbiol. 41:383–407.Google Scholar
  104. Riley, L. W., L. N. Junio, L. B. Libaek, and G. K. Schoolnik. 1987. Plasmid-encoded expression of lipo-polysaccharide O-antigenic polysaccharide in enteropathogenic Escherichia coli. Infect. Immun. 55:2052–2056.PubMedGoogle Scholar
  105. Riley, L. W., R. S. Remis, S. D. Helgerson, H. B. McGee, J. G. Wells, B. R. Davis, R. J. Hebert, E. S. Olcott, L. M. Johnson, N. T. Hargrett, P. A. Blake, and M. L. Cohen. 1983. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N. Engl. J. Med. 308:681–685.PubMedGoogle Scholar
  106. Robbins, J. B., G. H. McCracken Jr., E. C. Gotschlich, F. Ørskov, I. Ørskov, and L. Å. Hanson. 1974. Escherichia coli K1 capsular polysaccharide associated with neonatal meningitis. N. Engl. J. Med. 290:1216–1220.PubMedGoogle Scholar
  107. Ross, S., W. Rodriguez, G. Controni, G. Korengold, S. Watson, and W. Khan. 1975. Limulus lysate test for gram-negative bacterial meningitis: bedside application. J. Am. Med. Assoc. 233:1366–1369.Google Scholar
  108. Rothbaum, R. A., J. McAdams, R. Gianella, and J. C. Partin. 1982. A clinicopathologic study of enterocyte-adherent Escherichia coli: a cause of protracted diarrhea in infants. Gastroenterology 83:441–454.PubMedGoogle Scholar
  109. Rowe, B. 1979. The role of Escherichia coli in gastroenteritis. Clin. Gastroenterol. 8:625–644.PubMedGoogle Scholar
  110. Rowe, B., J. Taylor, and K. A. Bettelheim. 1970. An investigation of travellers’ diarrhea. Lancet i:l–5.Google Scholar
  111. Rubin, R. H. 1987. Infections of the urinary tract. Inf. Dis. Sci. Am. 7:1–10.Google Scholar
  112. Ryan, C. A., R. V. Tauxe, G. W. Hosek, J. G. Wells, P. A. Stoez, H. W. McFadden, P. W. Smith, G. F. Wright, and P. A. Blake. 1986. Escherichia coli 0157:H7 diarrhea in a nursing home: clinical, epidemiological, and pathological findings. J. Infect. Dis. 154:631–638.PubMedGoogle Scholar
  113. Sack, R. B., N. Hirschhorn, I. Brownlee, R. A. Cash, W. E. Woodward, and D. A. Sack. 1975. Enterotoxigenic E. coli associated diarrhoeal disease in Apache children. N. Engl. J. Med. 292:1041–1045.PubMedGoogle Scholar
  114. Sack, D. A., S. Huda, P. K. B. Neogi, R. R. Daniel, and W. M. Spira. 1980. Microtiter ganglioside enzyme- linked immunosorbent assay for Vibrio and Escherichia coli heat-labile enterotoxins and antitoxin. J. Clin. Microbiol. 11:35–40.PubMedGoogle Scholar
  115. Sack, D. A., J. C. McLaughlin, R. B. Sack, F. Ørskov, and I. Ørskov. 1977. Enterotoxigenic Escherichia coli isolated from patients at a hospital in Dacca. J. Infect. Dis. 135:275–280.PubMedGoogle Scholar
  116. Sack, D. A., and R. B. Sack. 1975. Test for enterotoxigenic Escherichia coli using Y1 adrenal cells in miniculture. Infect. Immun. 11:334–336.PubMedGoogle Scholar
  117. Saiki, R. K., T. L. Bugawan, G. T. Horn, K. B. Mullis, and H. A. Erlich. 1986. Analysis of enzymatically amplified -globin and HLA-DQ DNA with allele-specific oligonucleotide probes. Nature 324:163–666.PubMedGoogle Scholar
  118. Sanford, J. P. 1975. Urinary tract symptoms and infections. Ann. Rev. Med. 26:485.PubMedGoogle Scholar
  119. Sansonetti, P. J., T. L. Hale, G. J. Dammin, C. Kapfer, H. H. Collins Jr., and S. B. Formal. 1983. Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri. Infect. Immun. 39:1392–1402.PubMedGoogle Scholar
  120. Sansonetti, P. J., D. J. Kopecko, and S. B. Formal. 1981. Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence. Infect. Immun. 34:75–83.PubMedGoogle Scholar
  121. Scaletsky, I. C. A., M. L. M. Silva, and L. R. Trabulsi. 1984. Distinctive patterns of adherence of enteropathogenic Escherichia coli to HeLa cells. Infect. Immun. 45:534–536.PubMedGoogle Scholar
  122. Scharf, S. J., G. T. Horn, and H. A. Erlich. 1986. Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science 233:1076–1078.PubMedGoogle Scholar
  123. Scheckler, W. E. 1977. Septicemia in a community hospital. 1970 through 1973. J. Am. Med. Assoc. 237:1938–1941.Google Scholar
  124. Scheld, W. M., and J. P. Brodeur. 1983. Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis. Antimicrob. Agents Chemother. 23:108–112.PubMedGoogle Scholar
  125. Schumer, W. 1976. Steroids in the treatment of clinical septic shock. Ann. Surg. 184:333–341.PubMedGoogle Scholar
  126. Sereny, B. 1955. Experimental Shigella keratoconjunctivitis. Acta Microb. Acad. Sci. Hung. 2:293–296.Google Scholar
  127. Seriwatana, J., P. Echeverria, D. N. Taylor, T. Sakuldaipeara, S. Changchawalit, and O. Chivoratanond. 1987. Identification of enterotoxigenic Escherichia coli with synthetic alkaline phosphatase-conjugated oligonucleotide DNA probes. J. Clin. Microbiol. 25:1438–1441.PubMedGoogle Scholar
  128. Sever, J. L., J. H. Ellenbert, and D. Edmonds. 1978. Urinary tract infections during pregnancy: maternal and pediatric findings, p. 19–21. In: E. H. Kass, and W. Brumfitt. (ed.). Infections of the urinary tract. University of Chicago Press, Chicago.Google Scholar
  129. Small, P. L. C., R. R. Isberg, and S. Falkow. 1987. Comparison of the ability of enteroinvasive Escherichia coli, Salmonella typhimurium, Yersinia pseudotuberculosis, and Yersinia enterocolitica to enter and replicate within HEp-2 cells. Infect. Immun. 55:1674–1679.PubMedGoogle Scholar
  130. Speer, C. P., D. Hauptmann, P. Stubbe, and M. Gahr. 1985. Neonatal septicemia and meningitis in Gottingen, West Germany. Ped. Infect. Dis. 4:36–41.Google Scholar
  131. Spika, J. S., J. E. Parsons, D. Nordenberg, J. G. Wells, R. A. Gunn, and P. A. Blake. 1986. Hemolytic-uremic syndrome and diarrhea associated with Escherichia coli 0157:H7 in a day care center. J. Pediatr. 109:287–291.PubMedGoogle Scholar
  132. Sprung, C. L., P. V. Caralis, E. H. Marcial, M. Pierce, M. A. Gelbard, W. M. Long, R. C. Duncan, M. D. Tendler, and M. Karpf. 1984. The effects of high-dose corticosteroids in patients with septic shock: a prospective controlled study. N. Engl. J. Med. 311:1137–1143.PubMedGoogle Scholar
  133. Stamm, W. E. 1984. Prevention of urinary tract infections. Am. J. Med. 76(suppl): 148–154.PubMedGoogle Scholar
  134. Steeper, T. A., and J. McCullough. 1985. Platelet and granulocyte transfusion, p. 247–279. In: P. H. Wiernik, (ed). Contemporary issues in clinical oncology. Vol. 4. Leukemias and lymphomas. Churchill Livingstone, New York.Google Scholar
  135. Strockbine, N. A., L. R. Marques, J. W. Newland, H. W. Smith, R. K. Holmes, and A. D. O’Brien. 1986. Two toxin-converting phages from Escherichia coli 0157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities. Infect. Immun. 53:135–140.PubMedGoogle Scholar
  136. Svanborg Edén, C., R. Freter, L. Hagberg, R. Hull, H. Leffler, and G. K. Schoolnik. 1982. Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue. Nature 298:560–562.Google Scholar
  137. Svanborg Edén , C., L. Hagberg, L. Å. Hanson, T. Korhonen, H. Leffler, and S. Ollig. 1981. Adhesion of Escherichia coli in urinary tract infection, p. 161–187. In: K. Elliot, M. O’Connor, and J. Whelan (ed), Adhesion and microorganism pathogenicity. Ciba Foundation Symposium 80: Pitman Medical, Tunbridge Wells.Google Scholar
  138. Svanborg Edén, C., and H. A. Hansson. 1978. Escherichia coli pili as possible mediators of attachment to human urinary tract epithelial cells. Infect. Immun. 21:229–237.Google Scholar
  139. Svanborg Edén, C., L. Å. Hanson, U. Jodal, U. Lindberg, and A. S. Akerlund. 1976. Variable adherence to normal human urinary-tract epithelial cells of Escherichia coli strains associated with various forms of urinary tract infection. Lancet ii:490–492.Google Scholar
  140. Svennerholm, A. M.,and J. Holmgren. 1978. Identification of Escherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbent assay (GM1 ELISA) procedure. Curr. Microbiol. 1:19–23.Google Scholar
  141. Tacket, C. O., D. R. Maneval, and M. M. Levine. 1987. Purification, morphology, and genetics of a new fimbrial purtative colonization factor of enterotoxigenic Escherichia coli. Infect. Immun. 55:1063–1069.PubMedGoogle Scholar
  142. Thomas, L. V., A. Cravioto, S. M. Scotland, and B. Rowe. 1982. New fimbrial antigenic type (E8775) that may represent a colonization factor in enterotoxigenic Escherichia coli in humans. Infect. Immun. 35:1119–1124.PubMedGoogle Scholar
  143. Thomas, V., A. Shelokov, and M. Forland. 1979. Antibody-coated bacteria in the urine and the site of urinary-tract infection. N. Engl. J. Med. 290:588–590.Google Scholar
  144. Thompson, M. R., H. Brandwein, M. LaBine-Racke, and R. A. Gianella. 1984. Simple and reliable enzyme-linked immunosorbent assay with monoclonal antibodies for detection of Escherichia coli heat-stable enterotoxins. J. Clin. Microbiol. 20:59–64.PubMedGoogle Scholar
  145. Timmis, K. N., S. Sturm, and H. Watanabe. 1986. Genetic dissection of pathogenesis determinants of Shigella and enteroinvasive Escherichia coli, p. 107–126. In: J. Holmgren, A. Lindberg, and R. Mollby (eds.). Development of vaccines and drugs against diarrhea. 11th Nobel Conference. 1985. Studentlitterature, Lund, Sweden.Google Scholar
  146. Toledo, M. R. F., M. C. B. Alvariza, J. Murahovschi, S. R. T. S. Ramos, and L. R. Trabulsi. 1983. Enteropathogenic Escherichia coli serotypes and endemic diarrhea in infants. Infect. Immun. 39:586–589.PubMedGoogle Scholar
  147. Townsend, T. R., and R. P. Wentzel. 1981. Nosocomial bloodstream infections in a newborn intensive care unit. A case-matched control study of morbidity, mortality, and risk. Am. J. Epidemiol. 114:73–80.PubMedGoogle Scholar
  148. Tzipori, S., H. Karch I. K. Wachsmuth, R. M. Robins-Browne, A. D. O’Brien, H. Lior, M. L. Cohen, J. Smithers, and M. M. Levine. 1987. Role of a 60-mega-dalton plasmid and shiga-like toxins in the pathogenesis of infection caused by enterohemorrhagic Escherichia coli 0157:H7 in gnotobiotic pigs. Infect. Immun. 55:3117–3125.PubMedGoogle Scholar
  149. Veterans Administration Systemic Septis Cooperative Study Group. 1987. Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N. Engl. J. Med. 317:659–665.Google Scholar
  150. Vosti, K. L. 1975. Recurrent urinary tract infections: prevention by prophylactic antibiotics after sexual intercourse. J. Am. Med. Assoc. 231:934–940.Google Scholar
  151. Wallis, C., J. L. Melnick, and C. J. Longoria. 1981. Colorimetric method for rapid determination of bacteriuria. 14:342–446.Google Scholar
  152. Walz, W., M. A. Schmidt, A. F. Labigne-Roussel, S. Falkow, and G. K. Schoolnik. 1985. AFA-I, a cloned afibrial X-type adhesin from a human pyelonephritic Escherichia coli strain. Eur. J. Biochem. 152:315–321.PubMedGoogle Scholar
  153. Washington, J. A. 1975. Blood cultures. Principles and techniques. Mayo Clin. Proc. 50:91–98.Google Scholar
  154. Weinstein, M. P., J. R. Murphy, L. B. Reller, and K. A. Lichtenstein. 1983. The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. II. Clinical observations, with special reference to factors influencing prognosis. Rev. Infect. Dis. 5:54–70.PubMedGoogle Scholar
  155. Wolff, S. M. and J. V. Bennett. 1974. Gram-negative rod bacteremia. N. Engl. J. Med. 291:733–734.PubMedGoogle Scholar
  156. Wood, P. K., J. G. Morris Jr., P. L. C. Small, O. Sethabutr, M. R. F. Toledo, L. R. Trabulsi, and J. B. Kaper. 1986. Comparison of DNA probes and the Sereny test for identification of invasive Shigella and Escherichia coli strains. J. Clin. Microbiol. 24:498–500.PubMedGoogle Scholar
  157. Wu, T. C., E. C. Williams, S. Y. Koo, and J. D. MacLowry. 1985. Evaluation of three bacteriuria screening methods in a clinical hospital. J. Clin. Microbiol. 21:796–799.PubMedGoogle Scholar
  158. Young, L. S., W. J. Martin, R. D. Meyer, R. J. Weinstein, and E. T. Anderson. 1977. Gram-negative rod bacteremia: microbiologic, immunologic, and therapeutic considerations. Ann. Intern. Med. 86:456–471.PubMedGoogle Scholar
  159. Ziegler, E. J., J. A. McCutchan, J. Fierer, M. P. Glauser, J. C. Sadoff, H. Douglas, and A. I. Braude. 1982. Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N. Engl. J. Med. 307:1225–1230.PubMedGoogle Scholar

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