The Biology of Spinal Fusion

  • George F. Muschler
  • Joseph M. Lane
  • Edgar G. Dawson


This chapter is devoted to the discussion of the biology and biological principles of spinal fusion. Successful fusion is a critical element in the successful treatment in a large percentage of patients undergoing spinal surgery.1–7 Failed spinal fusions result in significant morbidity of spinal surgery patients. The incidence of pseudarthrosis ranges from 5% to 34% in large series,3,7,8 although generally lower in fusions for idiopathic scoliosis.


Bone Graft Bone Morphogenetic Protein Spinal Fusion Graft Material Demineralized Bone Matrix 
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Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • George F. Muschler
  • Joseph M. Lane
  • Edgar G. Dawson

There are no affiliations available

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