Malaria: Plasmodium falciparum (Welch 1898), Plasmodium vivax (Grassi and Filetti 1889), Plasmodium ovale (Stephens 1922), Plasmodium malariae (Laveran 1881)

  • Dickson D. Despommier
  • Robert W. Gwadz
  • Peter J. Hotez
Chapter

Abstract

Malaria is a mosquito-borne infection caused by protozoa of the genus Plasmodium. Humans are commonly infected by four species of the parasite: P. falciparum, P. vivax, P. ovale, and P. malariae. On rare occasions, certain species of Plasmodium that usually have simian hosts also infect humans.

Keywords

Plasmodium Falciparum Falciparum Malaria Cerebral Malaria Vivax Malaria Asexual Stage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Harrison G: Mosquitoes, Malaria, and Man. E.P. Dutton, New York, 1978Google Scholar
  2. 2.
    Bruce-Chwatt LJ: History of malaria from prehistory to eradication. In Wernsdorfer WH, McGregor SI (eds) Malaria, Principles and Practice of Malariology. Churchill Livingstone, Edinburgh, 1988, pp 1–59Google Scholar
  3. 3.
    Haggis AW: Fundamental errors in the early history of cinchona. Bull Hist Med 10:567–568, 1941Google Scholar
  4. 4.
    Garnham PCC: Malaria parasites of man: life cycles and morphology (excluding ultrastructure). In Wernsdorfer WH, McGregor SI (eds) Malaria, Principles and Practice of Malariology. Churchill Livingstone, Edinburgh, 1988, pp 61–96Google Scholar
  5. 5.
    Coatney GR, Collins WE, Warren M, et al: The Primate Malarias. US Department of Health, Education and Welfare, Bethesda, 1971Google Scholar
  6. 6.
    Meis JEGM, Verhave JP, Jap PHK, Meuwissen JHE: An ultrastructural study on the role of Kupffer cells in the process of infection by Plasmodium berghei sporozoites in rats. Parasitology 86: 231–242, 1983PubMedCrossRefGoogle Scholar
  7. 7.
    Hollingdale MR: Malaria and the liver. Hepatology 5:327–335, 1983CrossRefGoogle Scholar
  8. 8.
    Coatney GR: Relapse in malaria—an enigma. J Parasitol 62:3–9, 1976PubMedCrossRefGoogle Scholar
  9. 9.
    Schmidt LH: Compatibility of relapse patterns of Plasmodium cynomolgi infections in rhesus monkeys with continuous cyclical development and hypnozoite concepts of relapse. Am J Trop Med Hyg 35:1077–1099, 1986PubMedGoogle Scholar
  10. 10.
    Krotoski WA: Discovery of the hypnozoite and a new theory of malarial relapse. Trans R Soc Trop Med Hyg 79:1–11, 1985PubMedCrossRefGoogle Scholar
  11. 11.
    Dvorak, JSA, Miller LH, Whitehouse WC, et al: Invasion of erythrocytes by malaria merozoites. Science 187:748–750, 1975PubMedCrossRefGoogle Scholar
  12. 12.
    Aikawa M, Miller LH, Johnson J, et al: Erythrocyte entry by malaria parasites, a moving junction between erythrocyte and parasite. J Cell Biol 77:72–82, 1978PubMedCrossRefGoogle Scholar
  13. 13.
    Garvey G, Neu HC, Katz M: Transfusion-induced malaria after open heart surgery. NY State J Med 75:602–603, 1975Google Scholar
  14. 14.
    Covell G: Congenital malaria. Trop Dis Bull 47: 1147–1167, 1950PubMedGoogle Scholar
  15. 15.
    Spielman A, Perrone JB: Rapid diagnosis of malaria. Lancet 1:797, 1989Google Scholar
  16. 16.
    Snounou G, Viriyakosol S, Jarra W, et al: Identification of the four human malaria species in field samples by the polymerase chain reaction and detection of a high prevalence of mixed infections. Mol Biochem Parasitol 58:283–292, 1993PubMedCrossRefGoogle Scholar
  17. 17.
    World Health Organization: Severe and complicated malaria. Trans R Soc Trop Med Hyg 80(Suppl):l–50, 1986Google Scholar
  18. 18.
    MacPherson GG, Warrell MJ, White NJ, et al: Human cerebral malaria: a quantitative ultra-structural analysis of parasitized erythrocyte sequestration. Am J Pathol 119:385–401, 1985PubMedGoogle Scholar
  19. 19.
    Ruangjirachuporn W, Afzelius BA, Paulie S, et al: Cytoadherence of knobby and knobless Plasmodium falciparum. Parasitology 102:325–334, 1991PubMedCrossRefGoogle Scholar
  20. 20.
    Udeinya I, Schmidt JA, Aikawa M, et al: Falciparum malaria-infected erythrocytes bind to cultured human endothelial cells. Science 213: 555–557, 1981PubMedCrossRefGoogle Scholar
  21. 21.
    Chisti AH, Andrabi KI, Derick LM, et al: Isolation of skeleton-associated knobs from human blood cells infected with the malaria parasite Plasmodium falciparum. Mol Biochem Parasitol 52:293–297, 1992CrossRefGoogle Scholar
  22. 22.
    Looareesuwan S, Ho M, Wattanagoon Y, et al: Dynamic alteration in splenic function during acute falciparum malaria. N Engl J Med 317: 675–679, 1987PubMedCrossRefGoogle Scholar
  23. 23.
    Greenwood BM, Fakunle YM: The tropical splenomegaly syndrome: a review of its pathogenesis. In The Role of the Spleen in the Immunology of Parasitic Diseases. Tropical Disease Research Series 1. Schwabe, Basel, 1979, pp 229–244Google Scholar
  24. 24.
    Bruce-Chwatt ZJ: Malaria. In Jelliffe DB, Stanfield JP (eds) Diseases of Children in the Subtropics and Tropics (3rd ed). Edward Arnold, London, 1978, pp 827–856Google Scholar
  25. 25.
    Whittle HC, Brown J, Marsh K, Greenwood BM, et al: T-cell control of Epstein-Barr virus-infected B cells is lost during P. falciparum malaria. Nature 312:449–450, 1984PubMedCrossRefGoogle Scholar
  26. 26.
    Allison AC: Protection afforded by sickle-cell trait against subtertian malarial infection. BMJ 1: 290–294, 1954PubMedCrossRefGoogle Scholar
  27. 27.
    Dean J, Schecter AN: Sickle-cell anemia: molecular and cellular basis of therapeutic approaches [first of three parts]. N Eng J Med 296:752–763, 1978CrossRefGoogle Scholar
  28. 28.
    Dean J, Schecter AN: Sickle-cell anemia: molecular and cellular basis of therapeutic approaches [second of three parts]. 299:804–811, 1978Google Scholar
  29. 29.
    Dean J, Schecter AN: Sickle-cell anemia: molecular and cellular basis of therapeutic approaches [third of three parts]. 299:863–870, 1978Google Scholar
  30. 30.
    Miller LH: The challenge of malaria. Science 257:36–37, 1992PubMedCrossRefGoogle Scholar
  31. 31.
    Friedman, MJ: Ultrastructural damage to the malaria parasite in the sickled cell. J Protozool 26: 195–199, 1979PubMedGoogle Scholar
  32. 32.
    Friedman, MJ, Roth EF, Nagel RL, et al: Plasmodium falciparum: physiological interactions with human sickle cells. Exp Parasitol 47:73–80, 1979PubMedCrossRefGoogle Scholar
  33. 33.
    Bunn HF, Forget BG: Hemoglobin: Molecular, Genetic, and Clinical Aspects. Saunders, Philadelphia, 1986, p 690Google Scholar
  34. 34.
    Abu-Zeid YA, Theander TG, Abdulhadi NH, et al: Modulation of the cellular immune response during Plasmodium falciparum infections in sickle trait individuals. Clin Exp Immunol 88: 112-118, 1992PubMedCrossRefGoogle Scholar
  35. 35.
    Jarolim P, Palek J, Amato D, et al: Deletion in erythrocyte band 3 gene in malaria-resistant Southeast Asian ovalocytosis. Proc Natl Acad Sci USA 88:11022-11026, 1991PubMedCrossRefGoogle Scholar
  36. 36.
    Luzzi GA, Merry AH, Newbold CI, et al: Surface antigen expression on Plasmodium falciparum-infected erythrocytes is modified in alpha- and beta-thalassemia. J Exp Med 173:785–791, 1991PubMedCrossRefGoogle Scholar
  37. 37.
    Adams JH, Sim BKL, Dolan SA, et al: A family of erythrocyte binding proteins of malaria parasites. Proc Natl Acad Sci USA 89:7085–7089, 1992PubMedCrossRefGoogle Scholar
  38. 38.
    Gyang FN, Peterson DS, Wellems TE: Rapid detection of dihydrofolate reductase mutations that confer resistance to cycloguanil and pyrimethamine. Exp Parasitol 74:470–472, 1992PubMedCrossRefGoogle Scholar
  39. 39.
    Beier JC, Perkins PV, Wirtz RA, et al: Field evaluation of an enzyme-linked immunosorbent assay (ELISA) for Plasmodium falciparum sporozoite detection in anopheline mosquitoes from Kenya. Am J Trop Med Hyg 36:459–468, 1987PubMedGoogle Scholar
  40. 40.
    Bjorkman A: Drug resistance-changing pattern. In Target GAT (ed) Malaria: Waiting for the Vaccine. Wiley, Chichester, 1991, pp 105–121Google Scholar
  41. 41.
    Med Lett Drugs Ther 35:111–122, 1993Google Scholar
  42. 42.
    Miller KD, Lobel HO, Satriale RF, et al: Severe cutaneous reactions among American travelers using pyrimethamine-sulfadoxine (FansidarR) for malaria prophylaxis. Am J Trop Med Hyg 35: 451–458, 1986PubMedGoogle Scholar
  43. 43.
    Rouveix B, Bricaire F, Michon C, et al: Mefloquine and an acute brain syndrome. Ann Intern Med 110:577–578, 1989PubMedGoogle Scholar
  44. 44.
    Porter CH, Collins FH: Susceptibility of Anopheles hermsi to Plasmodium vivax. Am J Trop Med Hyg 42:414–416, 1990PubMedGoogle Scholar
  45. 45.
    Greenwood BM: Malaria chemoprophylaxis in endemic regions. In Target GAT (ed) Malaria: Waiting for the Vaccine. Wiley, Chichester, 1991, pp 83–104Google Scholar
  46. 46.
    Murphy GS, Basri H, Purnomo, et al: Vivax malaria resistant to treatment and prophylaxis with chloroquine. Lancet 341:96–100, 1993PubMedCrossRefGoogle Scholar
  47. 47.
    Lin LB: Bednets treated with pyrethroids for malaria control. In Target GAT (ed) Malaria: Waiting for the Vaccine. Wiley, Chichester, 1991, pp 67–82Google Scholar
  48. 48.
    Greenwood BM: A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, West Africa. Trans R Soc Trop Med Hyg 87(Suppl 2): 1–60, 1993Google Scholar
  49. 49.
    James AA: Mosquito molecular genetics: the hands that feed bite back. Science 257:37–38, 1992PubMedCrossRefGoogle Scholar
  50. 50.
    Gwadz RW: Genetic approaches to malaria control: how long the road? Am J Trop Med Hyg (in press) 1994Google Scholar
  51. 51.
    Sudre P, Breman JG, McFarland D, Koplan JP: Treatment of chloroquine-resistant malaria in African children: a cost-effectiveness analysis. Int J Epidemiol 21:146–154, 1992PubMedCrossRefGoogle Scholar
  52. 52.
    Foster SDF: The distribution and use of antimalarial drugs—not a pretty picture. In Target GAT (ed) Malaria: Waiting for the Vaccine. Wiley, Chichester, 1991, pp 123–139Google Scholar
  53. 53.
    Miller LH, Howard RJ, Carter R, et al: Research toward malaria vaccines. Science 234: 1349–1356, 1986PubMedCrossRefGoogle Scholar
  54. 54.
    Oaks SC, Mitchell VS, Pearson GW, Carpenter CCJ: Malaria: Obstacles and Opportunities. National Academy Press, Washington, DC, 1991, pp 169–210Google Scholar
  55. 55.
    Valero MV, Amador LR, Galindo C, et al: Vaccination with Spf66, a chemically synthesized vaccine against Plasmodium falciparum malaria in Colombia. Lancet 341:705–710, 1993PubMedCrossRefGoogle Scholar
  56. 56.
    Ballow WR, Hoffman SL, Sherwood MR, et al: Safety and efficacy of a recombinant DNA Plasmodium falciparum sporozoite vaccine. Lancet 1:1277–1281, 1987Google Scholar
  57. 57.
    Herrington DA, Clyde DF, Hosonsky M, Cortesia M, et al: Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Nature 328: 257–259, 1987PubMedCrossRefGoogle Scholar
  58. 58.
    Marsh K, Howard RJ: Antigens induced on erythrocytes by P. falciparum: expression of diverse and converged determinants. Science 231: 150–153, 1986PubMedCrossRefGoogle Scholar
  59. 59.
    Howard RJ: Antigenic variation of bloodstage malaria parasites. Philos Trans R Soc London [Biol] 307:141–158, 1984CrossRefGoogle Scholar
  60. 60.
    Kaslow DC: Toward a transmission-blocking vaccine for malaria. Vaccine Res 2:197–205, 1993Google Scholar

Copyright information

© Springer-Verlag New York, Inc. 1995

Authors and Affiliations

  • Dickson D. Despommier
    • 1
  • Robert W. Gwadz
    • 2
  • Peter J. Hotez
    • 3
  1. 1.College of Physicians and SurgeonsColumbia University, Presbyterian HospitalNew YorkUSA
  2. 2.Laboratory of Malaria Research, National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaUSA
  3. 3.Yale University School of MedicineNew HavenUSA

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