Microencapsulated Islets in Type I Diabetics: Clinical Experience

  • Patrick Soon-Shiong
Chapter

Abstract

Nonencapsulated pancreatic islets, transplanted into Type I diabetic patients, have generally yielded disappointing results because immune rejection has remained a major obstacle to successful treatment, espite the use of high-dose immunosuppressive egimens. Immunosuppressive drugs are necessary for transplantation of organs or tissues directly into human patients, but severe side effects frequently limit their continued use and diminish their therapeutic effectiveness.

Keywords

Human Islet Islet Transplantation Insulin Requirement Insulin Independence Islet Cell Transplantation 
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© Springer Science+Business Media New York 1999

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  • Patrick Soon-Shiong

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