The Function of Normal and Familial Hypertrophic Cardiomyopathy-Associated Tropomyosin

  • Rethinasamy Prabhakar
  • Kathy Pieples
  • Ganapathy Jagatheesan
  • Stephanie Burge
  • David F. Wieczorek
Chapter
Part of the Cardiovascular Molecular Morphogenesis book series (CARDMM)

Abstract

This review will focus on the role of sarcomeric tropomyosin during the assembly and function of thin filaments in striated muscle. Particular emphasis will be devoted to how mutations in familial hypertrophic cardiomyopathy influence these processes. Due to the complex and extensive nature of this topic, this review will not address the role of tropomyosin in the cytoskeleton; however, excellent articles on this topic have addressed this area (Lin et al., 1988; Hegmann et al., 1989).

Keywords

Thin Filament Indirect Flight Muscle Nemaline Myopathy Troponin Complex Mutant Heart 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Rethinasamy Prabhakar
  • Kathy Pieples
  • Ganapathy Jagatheesan
  • Stephanie Burge
  • David F. Wieczorek

There are no affiliations available

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