Salvage Esophagectomy for Persistent or Recurrent Disease After Definitive Chemoradiotherapy

Chapter
First Online:
Part of the Difficult Decisions in Surgery: An Evidence-Based Approach book series (DDSURGERY, volume 1)

Abstract

It is not uncommon for patients to either undergo definitive chemoradiotherapy with the expectation that locally recurrent tumor may possibly be treated by ‘salvage’ esophagectomy, or that patients be treated with chemoradiothearpy followed by selective use of surgery in cases of persistent disease. The literature supporting use of salvage esophagectomy is sparse. Nevertheless, esophagectomy has been shown to result in better survival than what can be achieved by either supportive care or non-operative strategies. Consideration should be given to performing salvage esophagectomy in carefully selected patients with persistent or recurrent cancer who are physiologically fit and who have a high likelihood of being able to undergo complete resection of their tumor.

Keywords

Esophageal cancer Esophagectomy Recurrent cancer Salvage esophagectomy Neoadjuvant therapy Chemoradiotherapy 
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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of Thoracic and Cardiovascular SurgeryUniversity of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Research Medical LibraryThe University of Texas MD Anderson Cancer CenterHoustonUSA

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