General Considerations and Etiologies of Aortic Stenosis

Chapter

Abstract

The earliest descriptions of aortic stenosis are credited to Riverius in 1646 where he provided a clear-cut description of the observed pathological findings of calcified aortic valve cusps in association with weak and diminished peripheral pulses. Aortic stenosis was described again by Bonet in 1679, however, John Baptist Morgagni, professor of anatomy in the University of Padua, referred to aortic stenosis in 1761 and is credited in providing a brilliant description of an autopsy specimen of calcified aortic valve cusps found in a patient and suggested the valve was both stenotic and incompetent. In his description, he quoted a similar case described by Georgius Greiselius and he clarified the anatomical and pathophysiological features of acquired aortic stenosis. In 1806, Corvisart provided another impressive correlation of clinical and autopsy findings and in 1854, William Stokes provided yet another vivid description of the disease. This chapter will provide a general overview of aortic stenosis as well as a review of the common etiologies of aortic stenosis.

Keywords

Aortic stenosis Etiology of aortic stenosis Left ventricular outflow tract (LVOT) Valvular aortic stenosis Supra-valvular aortic stenosis Sub-valvular aortic stenosis Epidemiology of aortic stenosis Causes of aortic stenosis 
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© Springer-Verlag London 2015

Authors and Affiliations

  1. 1.Department of Cardiovascular MedicineBeaumont Health, Oakland University/William Beaumont School of MedicineRoyal OakUSA

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