Hypertrophic Cardiomyopathy

  • Wojciech Mazur
  • Marilyn J. Siegel
  • Tomasz Miszalski-Jamka
  • Robert Pelberg
Chapter

Abstract

Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease characterized by diffuse or segmental left ventricle (LV) hypertrophy associated with a nondilated ventricular chamber, in the absence of other cardiac or systemic disease that might be capable of producing the same degree of hypertrophy [1]. It is an important cause of sudden cardiac death in any age group. The prevalence of HCM is approximately 0.2–0.5 % of the general population.

Keywords

Left Ventricle Fabry Disease Glycogen Storage Disease Cardiac Sarcoidosis Noonan Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Maron BJ, McKenna WJ, Danielson GK, Kappenberger LJ, Kuhn HJ, Seidman CE, et al. Task Force on Clinical Expert Consensus Documents. American College of Cardiology, Committee for Practice Guidelines. European Society of Cardiology American college of Cardiology/European society of cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the american college of cardiology foundation task force on clinical expert consensus documents and the european society of cardiology committee for practice guidelines. J Am Coll Cardiol. 2003;42:1687–713.PubMedCrossRefGoogle Scholar
  2. 2.
    Soor GS, Luk A, Ahn E, Abraham JR, Woo A, Ralph-Edwards A, et al. Hypertrophic cardiomyopathy: current understanding and treatment objectives. J Clin Pathol. 2009;62:226–35. doi: 10.1136/jcp.2008.061655.PubMedCrossRefGoogle Scholar
  3. 3.
    Chun EJ, Choi SI, Jin KN, Kwag HJ, Kim YJ, Choi BW, et al. Hypertrophic cardiomyopathy: assessment with MR imaging and multidetector CT. Radiographics. 2010;30:1309–28. doi: 10.1148/rg.305095074.PubMedCrossRefGoogle Scholar
  4. 4.
    Ghersin E, Lessick J, Litmanovich D, Engel A, Reisner S. Comprehensive multidetector CT assessment of apical ­hypertrophic cardiomyopathy. Br J Radiol. 2006;79:e200–4. doi: 10.1259/bjr/53601277.PubMedCrossRefGoogle Scholar
  5. 5.
    Saito H, Naito H, Takamiya M, Hamada S, Imakita S, Ohta M. Late enhancement of the left ventricular wall in hypertrophic cardiomyopathy by ultrafast computed tomography: a comparison with regional myocardial thickening. Br J Radiol. 1991;64:993–1000.PubMedCrossRefGoogle Scholar
  6. 6.
    Shiozaki AA, Santos TS, Artega E, Rochitte CE. Images in cardiovascular medicine. myocardial delayed enhancement by computed tomography in hypertrophic cardiomyopathy. Circulation. 2007;115:e430–1.PubMedCrossRefGoogle Scholar
  7. 7.
    Okayama S, Uemura S, Soeda T, Horii M, Saito Y. Role of cardiac computed tomography in planning and evaluating percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy. J Cardiovasc Comput Tomogr. 2010;4:62–5. doi: 10.1016/j.jcct.2009.10.004.PubMedCrossRefGoogle Scholar
  8. 8.
    Ghersin E, Soto V, Heldman AW. Multidetector computerized tomography can guide and document alcohol septal ablation in hypertrophic obstructive cardiomyopathy. Circulation. 2011;123:e5–7. doi: 10.1161/CIRCULATIONAHA.110.975599.PubMedCrossRefGoogle Scholar
  9. 9.
    Chen CC, Chen MT, Lei MH, Hsu YC, Chung SL, Sung YJ. Assessing myocardial bridging and left ventricular configuration by 64-slice computed tomography in patients with apical hypertrophic cardiomyopathy presenting with chest pain. J Comput Assist Tomogr. 2010;34:70–4.PubMedCrossRefGoogle Scholar
  10. 10.
    Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA. 2002;287:1308–20.PubMedCrossRefGoogle Scholar
  11. 11.
    Otto CM. Textbook of clinical echocardiography. Philadelphia: Saunders/Elsevier; 2009. p. 217–9.Google Scholar
  12. 12.
    Maron MS, Rowin EJ, Lin D, Appelbaum E, Chan RH, Gibson CM, et al. Prevalence and clinical profile of myocardial crypts in hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2012;5(4):441–7. doi: 10.1161/CIRCIMAGING.112.972760.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Wojciech Mazur
    • 1
  • Marilyn J. Siegel
    • 2
  • Tomasz Miszalski-Jamka
    • 3
    • 4
  • Robert Pelberg
    • 1
  1. 1.The Christ Hospital Heart and Vascular Center of Greater CincinnatiThe Lindner Center for Research and EducationCincinnatiUSA
  2. 2.Mallinckrodt Institute of RadiologyWashington University School of MedicineSt. LouisUSA
  3. 3.Department of Clinical Radiology and Imaging Diagnostics4th Military HospitalWrocławPoland
  4. 4.Center for Diagnosis Prevention and TelemedicineJohn Paul II HospitalKrakówPoland

Personalised recommendations