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Pancreas Transplantation

  • Amit D. TevarEmail author
  • Abhinav Humar
  • Amer H. Zureikat
  • Khalid O. Khwaja
  • A. Osama Gaber
  • M. Hosein Shokouh-Amiri
  • Miquel Tan
  • Raja Kandaswamy
  • Rainer W. G. Gruessner
  • David E. R. Sutherland
Chapter

Abstract

Diabetes mellitus is a significant burden to patients in the United States, with an estimated 10–15 % of the population affected. It remains a major cause of death within the United States. As described by the Diabetes Control and Complications Trial, intensive insulin-based therapy delays the onset and slows the progression of secondary complications of diabetes. These complications include retinopathy, neuropathy, and nephropathy. Although the insulin treatment regimens and modalities have advanced considerably over the past several decades, no patient can truly achieve euglycemia. Patients who are able to maintain very low serum blood sugars have a significantly increased incidence of hypoglycemic incidents, leading to morbidity, decreased quality of life, and mortality.

Keywords

Pancreas transplant Surgical technique Operative technique Pancreas-kidney transplant SPK transplant Living donor pancreas transplant Donor evaluation Complications Simultaneous pancreas kidney transplant Pancreas transplant alone Bladder drainage Living donor pancreas transplant Pancreas bench preparation 

Notes

Acknowledgments

A. Osama Gaber and Hosein Shoukouh-Amiri acknowledge the expert assistance of Dr. Mohammad Shokouh-Amiri for preparation of the illustrations and Mrs. Shaherah Rankins-Amos for assistance with manuscript preparation for the section “Simultaneous Pancreas Kidney: Portal/Enteric Drainage”.

Supplementary material

Video 6.1

Benching the pancreas from a deceased donor (Humar) (WMV 156889 kb)

Video 6.2

Pancreas transplant alone: systemic/bladder drainage (Humar) (WMV 110701 kb)

Video 6.3

Simultaneous pancreas kidney (SPK) transplant: portal/enteric drainage (Hosein Shokouh-Amiri, Osama Gaber) (WMV 135741 kb)

Video 6.4

Laparoscopic nephrectomy and distal pancreatectomy for living donor kidney and pancreas transplant (Miguel Tan, Raja Kandaswamy, Rainer Gruessner) (WMV 151967 kb)

Video 6.5

Total pancreatectomy islet auto transplant (Humar, Wijkstrom, Sturdevant) (MOV 642312 kb)

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Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  • Amit D. Tevar
    • 1
    Email author
  • Abhinav Humar
    • 2
  • Amer H. Zureikat
    • 3
  • Khalid O. Khwaja
    • 4
  • A. Osama Gaber
    • 5
  • M. Hosein Shokouh-Amiri
    • 6
  • Miquel Tan
    • 7
  • Raja Kandaswamy
    • 8
  • Rainer W. G. Gruessner
    • 9
  • David E. R. Sutherland
    • 10
  1. 1.Department of Surgery, Thomas E. Starzl Transplantation InstituteUniversity of Pittsburgh Medical Center, MontefiorePittsburghUSA
  2. 2.Division of Transplantation, Department of Surgery, Thomas E. Starzl Transplantation InstituteUniversity of Pittsburgh Medical Center, MontefiorePittsburghUSA
  3. 3.Department of SurgeryUniversity of PittsburghPittsburghUSA
  4. 4.Department of SurgeryBeth Israel Deaconess Medical CenterBostonUSA
  5. 5.Department of SurgeryThe Methodist Hospital/Cornell UniversityHoustonUSA
  6. 6.Department of SurgeryLouisiana State University Health Science CenterShreveportUSA
  7. 7.Kidney and Pancreas TransplantationPiedmont Transplant Institute, Piedmont HospitalAtlantaUSA
  8. 8.Division of TransplantationUniversity of MinnesotaMinneapolisUSA
  9. 9.Department of SurgeryUniversity of ArizonaTucsonUSA
  10. 10.Department of Surgery MMC 280University of Minnesota HospitalMinneapolisUSA

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