Rheumatic Mitral Valve Disease

  • Narain Moorjani
  • Bushra S. Rana
  • Francis C. Wells


A 45 year-old lady presented with a long-standing history of increasing dyspnoea on exertion, associated with fatigue and lethargy. She had a previous history of rheumatic fever as a child and had been followed up with serial echocardiography. Clinical examination revealed a pan-systolic and mid-diastolic murmur, both loudest at the apex.


Rheumatic mitral valve disease Rheumatic fever Lancefield group A β-haemolytic streptococcal infection Restricted leaflet motion Calcified thickened sub-valvular apparatus Commissural fusion Commissurotomy Leaflet augmentation Mitral valve replacement Papillary muscle splitting 

Recommended Reading

  1. Antunes MJ. Repair of rheumatic mitral valve regurgitation: how far can we go? Eur J Cardiothorac Surg. 2013;44(4):689–91.CrossRefGoogle Scholar
  2. Dillon J, Yakub MA, Nordin MN, Pau KK, Krishna Moorthy PS. Leaflet extension in rheumatic mitral valve reconstruction. Eur J Cardiothorac Surg. 2013;44(4):682–9.CrossRefGoogle Scholar
  3. Lee EM, Shapiro LM, Wells FC. Importance of subvalvular preservation and early operation in mitral valve surgery. Circulation. 1996;94(9):2117–23.CrossRefGoogle Scholar
  4. Mihos CG, Pineda AM, Capoulade R, Santana O. A systematic review of mitral valve repair with autologous pericardial leaflet augmentation for rheumatic mitral regurgitation. Ann Thorac Surg. 2016;102(4):1400–5.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Ltd., part of Springer Nature 2018

Authors and Affiliations

  • Narain Moorjani
    • 1
  • Bushra S. Rana
    • 2
  • Francis C. Wells
    • 1
  1. 1.Department of Cardiothoracic SurgeryRoyal Papworth HospitalCambridgeUK
  2. 2.Department of CardiologyRoyal Papworth HospitalCambridgeUK

Personalised recommendations