Phenotypic Changes in Staphylococcal Cell Surface Characteristics Associated with Growth in Human Peritoneal Dialysis Fluid
Growth of Staphylococcus epidermidis clinical isolates in pooled human peritoneal dialysate (HPD) resulted in the generation of surface characteristics unique to this environment. Comparison of cell wall and membrane protein profiles of bacteria grown in HPD or Nutrient Broth revealed considerable differences. In particular, two highly immunogenic, iron-repressible membrane proteins, which may function as siderophore receptors, were induced in HPD-grown cells.
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