A Makeup Artist with Crohn’s Disease
Anti-TNF alpha therapy is a major advance in disease modifying treatments for autoimmune inflammatory diseases. However their increasing use has led to the recognition of immune mediated adverse events, in particular, immune-mediated demyelination of the CNS or PNS. Here we present a case of a multifocal motor neuropathy with conduction block associated with infliximab treatment for Crohn’s disease. Cessation of infliximab resulted in neurological recovery. This case highlights the importance of investigation, and consideration of discontinuation of medication, in patients reporting neurological symptoms in the context of anti-TNF alpha treatments.
KeywordsTNF alpha Demyelination Neuropathy Infliximab
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