Dietary Fibre and Plasma Lipids: Potential for Prevention and Treatment of Hyperlipidaemias

  • A. S. Truswell
  • A. C. Beynen
Part of the ILSI Human Nutrition Reviews book series (ILSI HUMAN)


One of the major postulates of the dietary fibre hypothesis (Trowell, 1972) was that coronary heart disease (CHD) is associated with diets low in fibre and a high-fibre diet may protect against CHD. The most obvious direct mechanism for such an effect is by reduction of plasma total and LDL-cholesterol, presumably by some interference with sterol metabolism which would have to start in the gastro-intestinal tract, since fibre is by definition indigestible (by human enzymes) and so not absorbable as such. It is difficult to visualise how any other direct mechanism could work, such as a reduced tendency to thrombosis, reduced blood pressure or reduced liability to dangerous cardiac arrhythmias, from eating more dietary fibre.


Bile Acid Dietary Fibre Wheat Bran Plasma Cholesterol Plasma Total Cholesterol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag London Limited 1992

Authors and Affiliations

  • A. S. Truswell
  • A. C. Beynen

There are no affiliations available

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