Chemoreception pp 489-495 | Cite as

Ventilatory Chemosensory Drive in Cats, Rats and Guinea-pigs

  • Ricardo Fernández
  • Ivette Arriagada
  • Ana-María Garrido
  • Carolina Larraín
  • Patricio Zapata
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 536)

Abstract

Comroe and Schmidt (1938) proposed that decreasing PaO2is the effective stimulus for arterial chemoreceptors (aortic and carotid bodies), but they considered that these peripheral chemoreceptors could not play a role in the ventilatory control in normoxia. Nevertheless, electrophysiological recordings from the carotid (sinus) nerves showed chemoreceptor activity at normoxic PaO2, which became feeble or absent when the animal was made hyperoxic by breathing pure oxygen (Landgren and Zotterman, 1951; Åstrand, 1954).

Keywords

Carotid Body Peripheral Chemoreceptor Ventilatory Depression Ventilatory Change Hypoxic Challenge 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Ricardo Fernández
    • 1
  • Ivette Arriagada
    • 1
  • Ana-María Garrido
    • 1
  • Carolina Larraín
    • 1
  • Patricio Zapata
    • 1
  1. 1.Laboratory of NeurobiologyCatholic University of ChileSantiagoChile

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