Adhesion/Growth-Regulatory Galectins: Insights into Their Ligand Selectivity Using Natural Glycoproteins and Glycotopes

  • Albert M. Wu
  • Tanuja Singh
  • Jia-Hau Liu
  • Sabine André
  • Martin Lensch
  • Hans-Christian Siebert
  • Mickael Krzeminski
  • Alexandre M. J. J. Bonvin
  • Herbert Kaltner
  • June H. Wu
  • Hans-Joachim Gabius
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 705)

Abstract

“Biochemistry text books commonly make it appear that it is a foregone conclusion that the hardware of biological information storage and transfer is confined to nucleotides and amino acids, the letters of the genetic code. However, the remarkable talents of a third class of biomolecules are often overlooked” [1]. This statement from a recent review guides the readers to look at and fully appreciate the chemical/lectinochemical characteristics of carbohydrates that underlie the concept of the sugar code [2].

Keywords

Agglutinin Docking Glycosylation Lectin phylogeny Sugar code 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Albert M. Wu
    • 1
  • Tanuja Singh
  • Jia-Hau Liu
  • Sabine André
  • Martin Lensch
  • Hans-Christian Siebert
  • Mickael Krzeminski
  • Alexandre M. J. J. Bonvin
  • Herbert Kaltner
  • June H. Wu
  • Hans-Joachim Gabius
  1. 1.Glyco-Immunochemistry Research Laboratory, Institute of Molecular and Cellular Biology, College of MedicineChang-Gung UniversityKwei-Shan, Tao-YuanTaiwan

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