Role of Titin in Skeletal Muscle Function and Disease

  • Coen A. C. Ottenheijm
  • Henk GranzierEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 682)


This review covers recent developments in the titin field. Most recent reviews have discussed titin’s role in cardiac function: here we will mainly focus on skeletal muscle, and discuss recent advances in the understanding of titin’s role in skeletal muscle function and disease.


Striated muscle Sarcomere PEVK Titin isoforms Single molecule 


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of PhysiologyUniversity of ArizonaTucsonUSA

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