Generation and Selection of Surrogate Methods for Correlation Analysis

  • Sebastien Louis
  • Christian Borgelt
  • Sonja GrünEmail author
Part of the Springer Series in Computational Neuroscience book series (NEUROSCI, volume 7)


Generating artificial data from experimental data as a means for implementing a null hypothesis is becoming widely used. The reason is twofold: increasing computer power now allows for this type of approach, and it has become clear that the complexity of experimental data does not in general allow one to formulate a null hypothesis analytically. This is particularly true for the correlation analysis of parallel spike trains. Neglecting statistical features of experimental data can easily lead to the occurrence of false positive results, which of course needs to be avoided. Therefore surrogate data are used to generate the predictor by modifying the original data in such a way that the feature of interest (temporal coordination of spikes) is destroyed but other features of the data are preserved. The latter aspect is the most demanding and requires the selection of a surrogate type that best fits the data at hand. This chapter will demonstrate the need for such a selection and will show selection criteria.


False Positive Rate False Negative Rate Spike Train Surrogate Data Spike Time 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Sebastien Louis
    • 1
  • Christian Borgelt
    • 2
  • Sonja Grün
    • 1
    Email author
  1. 1.Laboratory for Statistical NeuroscienceRIKEN Brain Science InstituteWakoshiJapan
  2. 2.Intelligent Data Analysis and Graphical Models Research UnitEuropean Centre for Soft ComputingMieresSpain

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