Treatment of Osteosarcoma. The Scandinavian Sarcoma Group Experience

  • Øyvind S. BrulandEmail author
  • Henrik Bauer
  • Thor Alvegaard
  • Sigbjørn Smeland
Part of the Cancer Treatment and Research book series (CTAR, volume 152)


Results from four consecutive trials, conducted from 1982 by members of the Scandinavian Sarcoma Group, are reviewed. A total of 330 classical osteosarcoma patients were enrolled. In all trials chemotherapy was based on the three active drugs, methotrexate, doxorubicin and cisplatinum and for the latter trials also ifosfamide. Post-operative chemotherapy was stratified by histological response to up-front treatment.


Limb Salvage Poor Responder Histological Response Good Responder Overt Metastasis 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Øyvind S. Bruland
    • 1
    Email author
  • Henrik Bauer
  • Thor Alvegaard
  • Sigbjørn Smeland
  1. 1.The Norwegian Radium HospitalUniversity of OsloOsloNorway

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