Adipose Tissue–Muscle Interactions and the Metabolic Effects of n-3 LCPUFA – Implications for Programming Effects of Early Diet

Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 646)

Studies in adult animals as well as in humans have demonstrated beneficial effects of increased intake of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) on lipid metabolism, obesity, and insulin sensitivity. The lipid composition of breast milk, and in particular, the role of n-3 LCPUFA in imprinting of metabolism and its hormonal control need clarification as far as the long-term beneficial effects of breastfeeding on health are concerned. In this respect, animal studies have brought inconclusive results. However, the involvement of adipose tissue-muscle interactions in the short term effects of n-3 LCPUFA during perinatal development, as well as the lasting effects of n-3 LCPUFA intake, are likely to occur and should be further investigated.

Keywords

Adipose tissue muscle imprinting n-3 polyunsaturated fatty acids obesity insulin sensitivity 
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© Springer Science + Business Media B.V 2009

Authors and Affiliations

  1. 1.Department of Adipose Tissue BiologyInstitute of Physiology of the Academy of Sciences of the Czech Republic, v.v.i.VidenskaCzech Republic

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