Immunology of Norovirus Infection

  • Juan S. Leon
  • Menira Souza
  • Qiuhong Wang
  • Emily R. Smith
  • Linda J. Saif
  • Christine L. Moe


Noroviruses are the leading cause of epidemic non-bacterial gastroenteritis worldwide. Despite their discovery over three decades ago, little is known about the host immune response to norovirus infection. The purpose of this chapter is to review the field of norovirus immunology and discuss the contributions of outbreak investigations, human and animal challenge studies and population-based studies. This chapter will survey both humoral and cellular immunity as well as recent advances in norovirus vaccine development.


Norwalk Virus Histo Blood Group Antigen Lamina Propia STAT1 Knockout Mouse Infected Volunteer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Juan S. Leon
  • Menira Souza
  • Qiuhong Wang
  • Emily R. Smith
  • Linda J. Saif
  • Christine L. Moe
    • 1
  1. 1.Hubert Department of Global Health, Rollins School of Public HealthEmory UniversityAtlantaUSA

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