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RNA-Mediated Resistance to Cassava Geminiviruses in Transgenic Cassava

  • Hervé Vanderschuren
  • Rashid Akbergenov
  • Mikhail M. Pooggin
  • Thomas Hohn
  • Wilhelm Gruissem
  • Peng Zhang
Conference paper

Cassava mosaic disease (CMD) is one of the major problems encountered in cassava fields in Africa where the disease can trigger overall yield losses up to 25%. CMD is caused by whitefly-transmitted geminiviruses. Synergism, recombination and pseudo-recombination between different cassava geminivirus species have led to the recent pandemics of severe CMD in Africa (Legg and Fauquet, 2004). Our research aims at developing different CMD prevention strategies in transgenic cassava and therefore providing local farmers with geminivirus resistant lines to secure cassava production in the subsistence faming system.

Keywords

Small RNAs Transcriptional Gene Silence Cassava Mosaic Disease African Cassava Mosaic Virus Transgenic Cassava 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Akbergenov R, Si-Ammour A, Blevins T, Amin I, Kutter C, Vanderschuren H, Zhang P, Gruissem W, Meins F Jr, Hohn T, Pooggin MM (2006) Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Res 34(2): 462-471.CrossRefPubMedGoogle Scholar
  2. Legg JP, Fauquet CM (2004) Cassava mosaic geminiviruses in Africa. Plant Mol Biol 56: 585-599.CrossRefPubMedGoogle Scholar
  3. Zhang P, Vanderschuren H, Fütterer J, Gruissem W (2005) Resistance to cassava mosaic disease in transgenic cassava expressing antisense RNAs targeting virus replication genes. Plant Biotechnol J 3: 385-397.CrossRefPubMedGoogle Scholar

Copyright information

© Springer 2007

Authors and Affiliations

  • Hervé Vanderschuren
    • 1
  • Rashid Akbergenov
    • 2
  • Mikhail M. Pooggin
    • 2
  • Thomas Hohn
    • 2
  • Wilhelm Gruissem
    • 1
  • Peng Zhang
    • 1
  1. 1.Institute of Plant Sciences, ETH ZurichSwitzerland
  2. 2.Institute of BotanyUniversity of BaselSwitzerland

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