Abstract
The use of BioNOC II microcarriers in a fixed bed bioreactor setup allows to produce high protein levels in a CHO-320 cell line expressing constitutively interferon-γ and also with insect cells used with a baculovirus transient expression vector.
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References
Burteau, C. C., F. R. Verhoeye et al. (2003). “Fortification of a protein-free cell culture medium with plant peptones improves cultivation and productivity of an interferon-producing CHO cell line.” In Vitro Cellular and Developmental Biology 39: 291–296.
Ikonomou, L., G. Bastin et al. (2001). “Design of an efficient medium for insect cell culture and recombinant protein production.” In Vitro Cellular and Developmental Biology-Animal 37: 549–559.
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Drugmand, JC., Michiels J.-F., JF., Agathos, S., Schneider, YJ. (2007). Growth of Mammalian and Lepidopteran Cells on BioNOC® II Disks, a Novel Macroporous Microcarrier. In: Smith, R. (eds) Cell Technology for Cell Products., vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5476-1_143
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DOI: https://doi.org/10.1007/978-1-4020-5476-1_143
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5475-4
Online ISBN: 978-1-4020-5476-1
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