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In this introductionnary chapter, we present the wide range of current findings and research issues in longevity, and identify questions still unanswered that should be investigated in the years to come.

This review is based mostly upon work on human longevity published between 1998 and 2004. However, some older work is invoked given its continued importance today.We have followed a five-part plan, starting with demographic questions surrounding longevity (Part 1), followed by epidemiological questions on the health of extremely old people (Part 2).We then address strictly bio-demographic issues (Part 3) mixing biology and demography, most often in a family framework. Part 4 examines biological questions focusing on markers and on the role played by genes. A final part deals briefly with databases on human longevity.

Keywords

Research Issue Development Review Demographic Research Human Longevity Health Expectancy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Abbott, A. (2004) “Growing old gracefully”, Nature, 428:116-118.Google Scholar
  2. Abernethy, V., and Hip, R. (1990) “Parent characteristics and sex differential infant mortality: The case in Tennessee”, Human Biology, 62(2):279-290.Google Scholar
  3. Allard, M., and Robine, J.-M. (2000) Les centenaires fran çais. Etude de la Fondation IPSEN, 1990-2000. Paris: Serdi Edition.Google Scholar
  4. Allard, M., Vallin, J., Andrieux, J. M., and Robine, J.-M. (1996) “In search of the secret of centenarians: A demographic and medical survey about centenarians in France”. In: Caselli, G., Lopez, A. D. (eds.), Health and Mortality Among Elderly Populations. Oxford: Clarendon Press, pp. 61-86 (Chapter 4)Google Scholar
  5. Alter, G. (2004) “Height, frailty, and the standard of living : Modeling the effects of diet and disease on declining mortality and increasing height”, Population Studies, 58(3):265-279Google Scholar
  6. Ambra, R., Mocchegiani, E., Giacconi, R., Canali, R., Rinna, A., Malavolta, M., and Virgili, F. (2004) “Characterization of the hps70 response in lymphoblasts from aged and centenarian subjects and differential effectes of vitro zinc supplementation”, Experimental Gerontology, 39:1475-1484.Google Scholar
  7. Andersen-Ranberg, K., Christensen, K., Jeune, B. et al. (1999) “Declining physical abilities with age: A crosssectional study of older twins and centenarians in Denmark”, Age and Ageing, 28:373-377.Google Scholar
  8. Andersen-Ranberg, K., Vasegaard, L., and Jeune, B. (2001) “Dementia is not inevitable: A population-based study of Danish centenarians”, Journal of Gerontology: Psychososial Sciences, 56B(3):P152-P159.Google Scholar
  9. Ankri, J., and Poupard, M. (2003) “Pr évalence et incidence des d émences au grand âge. Analyse de la litt érature”, Rev. Epidemiol. Sant é Publique, 51:349-360.Google Scholar
  10. Arantes-Oliveira, N., Berman, J. R., and Kenyon, C. (2003) “Healthy animals with extreme longevity”, Science, 302:611.Google Scholar
  11. Arkhipov, I. J. A. (1980) “La long évit é : essai d’interpr étation du ph énom ène à partir de sa distribution g éographique”, La Revue de G ériatrie, 5(8):405-407.Google Scholar
  12. Atzmon, G., Gabriely, I., Greiner, W. et al. (2002) “Plasma HDL levels highly correlate with cognitive function in exceptional longevity”, Journal of Gerontology: Medical Sciences, 57A(11):M712-M715.Google Scholar
  13. Austad, S. (2005) “Patterns in mammalian aging: Demography and Evolution”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  14. Bagnara, G. P., Bonsi, L., Strippoli, P. et al. (2000) “Hemopoesis in healthy old people and centenarians”, Journal of gerontology: Biologocal Sciences, 55A(2):B61-B66.Google Scholar
  15. Baltes, P. B. (2003) “Extending longevity: Dignity gain or dignity drain”, Max Plank Research, 3:15-19.Google Scholar
  16. Barbi, E., Caselli, G., and Vallin, J. (2003) “Trajectories of extreme survival in heterogeneous populations”, Population, E58 (1): 43-66.Google Scholar
  17. Bartke, A., Coschigano, K., Kopchick, J. et al. (2001) “Genes that prolong life: Relationships of growth hormone and growth to aging and life span”, Journal of Gerontology: Biological Sciences, 56A(8):B340-B349.Google Scholar
  18. Barzilai, N. (2003) “Discovering the secrets of successful longevity”, Journal of Gerontology: Medical Sciences, 58A(3):225-226.Google Scholar
  19. Barzilai, N., Atzmon, G., Schechter, C., et al. (2003) “Unique lipoprotein phenotype and genotype associated with exceptional longevity”, The Journal of the American Medical Association, 290(15): 2030-2040.Google Scholar
  20. Barzilai, N., Gabriely, I., Gabriely, M., et al. (2001) “Offsring of centenarians have a favorable lipid profile”, Journal of the American Geriatric Society, 491:76-79.Google Scholar
  21. Barzilai, N., and Shuldiner, A. R. (2001) “Searching for human longevity genes: The future history of gerontology in the Post-genomic Era”, Journal of Gerontology: Biological Sciences, 56A(2):M83-M87.Google Scholar
  22. Beaumel, C., D ésesquelles, A., Richet-Mastain, L., and Vatan, M. (2004) La situation d émographique en 2002. Insee Soci ét é n 34.Google Scholar
  23. Bell, F. C., Wade, A. H., and Goss, S. G. (1992) Life Tables for the United States: 1900-2080. Actuarial Study, No. 107. SSA Publication No. 11-11536. Administration Office of Actuary.Google Scholar
  24. Benjamin, B. (1959) “Actuarial aspects of human lifespans”. In: Wolstenholme, G. E. W., O’Connor, M. (eds.), CIBA Foundation Colloquia on Ageing, Vol. 5, The Life Span of Animals. Boston: Little, Brown and Company, pp. 2-20.Google Scholar
  25. Benjamin, B. (1963) “Actuarial methods of mortality analysis: Adaptation to changes in the age and cause pattern”, Proceedings of the Royal Society, B159:1-255.Google Scholar
  26. Benjamin, B. (1964) “Demographic and actuarial aspects of ageing, with special reference to England and Wales”, Journal of the Institute of Actuaries, 90:211-253.Google Scholar
  27. Benjamin, B. (1982) “The span of life”, Journal of the Institute of Actuaries, 109:319-357.Google Scholar
  28. Benjamin, B. (1988) “Years of life lost and other mortality indices”, Journal of the Institute of Actuaries, 115:709-719.Google Scholar
  29. Bennett, N. G., and Garson, L. K. (1986) “Extraordinary longevity in the Soviet Union: Fact or artifact?” The Gerontologist, 26(4):358-361.Google Scholar
  30. Bertillon, J. (1878) “Discussion sur le bulletin-mod èle de mariage”, Annales de demographie internationale, 5:472-473.Google Scholar
  31. Bladbjerg, E. M., Andersen-Ranberg, K., de Maat, M. P. M., et al. (1999) “Longevity is independent of common variations in genes associated with cardiovascular risk”, Thrombosis and Haemostasis, 82:1100-1105.Google Scholar
  32. Blanch é, H. (2003) “Les facteurs g én étiques de la long évit é ”, Presse Medicale, 32:365-369.Google Scholar
  33. Blanch é, H., Cabanne, L., Sahbatou, M., et al. (2001) “A study of French centenarians: Are ACE and APOE associated with longevity?” CR Academic Science Life Sciences, 324:129-135.Google Scholar
  34. Blansjaar, B. A., Thomassen, R., and van Schaik, H. W. (2000) “Prevalence of dementia in centenarians”, International Journal of Geriatric Psychiatry, 15:219-225.Google Scholar
  35. Blazer, D. G., Fillenbaum, G., and Burchett, B. (2001) “The APOE-E4 allele and the risk of functional decline in a community sample of African American and white older adults”, Journal of Gerontology: Medical Sciences, 56A(12):M785-M789.Google Scholar
  36. Bocquet-Appel, J. P., and Jakobi, L. (1991) “La transmission familiale de la long évit é à Arthez d’Asson (1685-1975)”, Population, 46:327-347.Google Scholar
  37. Bodio, L. (1887) “Quelques renseignments sur les conditions hygieniques et sanitaires de l’Italie”, Bulletin de l’Institut international de statistique, II(part 1):264-84.Google Scholar
  38. Bodnar, A. G., Ouellette, M., Frolkis, M., et al. (1998) “Extension of life-span by introduction of telomerase into normal human cells”, Science, 279:349-352.Google Scholar
  39. Bonafe, M., Barbi, C., Storci, G., et al. (2002) “What studies on human longevity tell us about the risk for cancer in the oldest old: Data and hypotheses on the genetics and immunology of centenarians”, Experimental Gerontology, 37:1263-1271.Google Scholar
  40. Bonafe, M., Barbieri, M., Marchegiani, F., et al. (2003) “Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: Cues for an evolutionarily concerved mechanism of life span control”, Journal of Clinical Endocrinology and Metabolism, 88:3299-3304.Google Scholar
  41. Bongaarts, J., and Feeney, G. (2002) “How long do we live?”, Population and Development Review, 28(1):13-29.Google Scholar
  42. Bonneux, L., Barendregt, J. J., and Van der Maas, P. J. (1998) “The expiry date of man: A synthesis of evolutionary biology and public health”, Journal of Epidemiology and Community Health, 52:619-623.Google Scholar
  43. Boulding, K. (2003) “Possible consequences of increased life expectancy”, Population and Development Review, 29 (3):193-504.Google Scholar
  44. Bourbeau, R., and Desjardins, B. (2005) “Mortality at extreme ages and data quality: The Canadian experience”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  45. Bourgeois-Pichat, J. (1952) “Essai sur la mortalit é biologique de l’homme”, Population, 7(3):381-394Google Scholar
  46. Bourli ère, F. (1987) “Vieillissement “normal” et vieillissement pathologique”, Gerontologica Perspecta, 1:475-485.Google Scholar
  47. Bowerman, W. G. (1939) “Centenarians”, Transactions of Actuaries, 40:360-378.Google Scholar
  48. Buffon, G.L.L. (1749). Oeuvres Compl ètes. Paris: P Dum énil Editeur (Edition de 1836).Google Scholar
  49. Caldwell, J. C. (1979) “Education as a factor in mortality decline: An examination of Nigerian data”, Population Studies, 33(3):395-413.Google Scholar
  50. Campisi, J., Kim, S. H., Lim, C. S., et al. (2001) “Cellular senescence, cancer and aging: The telomere connection”, Experimental Gerontology, 36:1619-1637.Google Scholar
  51. Carey, J. R. (1997) “What demographers can learn from fruit fly actuarial models and biology”, Demography, 34(1):17-30.Google Scholar
  52. Carey, J. R. (2003) Longevity, the Biology and Demography of Life Span. Princeton: University Press.Google Scholar
  53. Carey, J., and Judge, D. S. (2005) “Life span extension in humans is self-reinforcing: A general theory of longevity”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  54. Carey, J. R., Liedo, P., Orozco, D., and Vaupel, J. W. (1992) “Slowing of mortality rates at older ages in large medfly cohorts”, Science, 258:457-461.Google Scholar
  55. Carey, J. R., Robine, J-M., Michel, J. P., and Christen, Y. (2005) Longevity and Frailty. Berlin: Springer.Google Scholar
  56. Carnes, B., and Olshansky, S. J. (1993) “Evolutionary perspectives on human senescence”, Population and Development Review, 19:793-806.Google Scholar
  57. Carnes, A. B., and Olshansky, S. J. (1997) “A biologically motivated partitioning of mortality”, Experimental Gerontology, 32(6):615-631.Google Scholar
  58. Carnes, B., Olshansky, S. J., and Grahn, D. (1996) “Continuing the search for a law of mortality”, Population and Development Review, 22:231-264.Google Scholar
  59. Carnes, B. A., Olshansky, S. J., and Grahn, D. (2003) “Biological evidence for limits to the duration of life”, Biogerontology, 4:31-45.Google Scholar
  60. Caselli, G., Vaupel, J., and Yashin, A. (2005) “Explanation of the decline in mortality among the oldest-old: A demographic point of view”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.) Human Longevity, individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  61. Catalano, R. (2002) “Economic antecedents of mortality among the very old”, Epidemiology, 13:133-137.Google Scholar
  62. Cawthon, R. M., Smith, K. R., O’brien, E., et al. (2003) “Association between telomere length in blood and mortality in people aged 60 years and older”, The Lancet, 361:393-395.Google Scholar
  63. Charbonneau, H. (1990). “Pierre Joubert a-t-il v écu 113 ans?” Mem Soc Geneal Can-Fr, 41:45-49.Google Scholar
  64. Charbonneau, H., and Desjardins, B. (1990) “Vivre cent ans dans la vall ée du Saint-Laurent avant 1800”, Annales de D émographie Historique, 218-226.Google Scholar
  65. Chen, C., Dewaele, S., Braeckman, B., Desmyter, L., Verstraelen, J., Borgonie, G., Vanfleteren, J., and Contreras, R. (2003) “A high-throughput screening system for genes extending life-span”, Experimental Gerontology, 38: 1051-1063.Google Scholar
  66. Cheung, J. (2001) The Long-Term Trend of Non-Maori Mortality and its More Recent Compression Effect. Presented at the Population Association of New Zealand biannual conference, Wellington.Google Scholar
  67. Cheung, S. L. K. (2003) Scalar Expansion and Normal Longevity in Hong Kong. Hong Kong University of Science and Technology. PhD Thesis.Google Scholar
  68. Cheung, S. L. K., Robine, J-M., Tu, E. J. C., and Caselli, G. (2005a) “Change in the distribution of normal life durations through the demographic transition: The case of Hong Kong”, (unpublished manuscript).Google Scholar
  69. Cheung, S. L. K., Robine, J-M., Tu, E. J. C., et al. (2005b) “Three dimensions of the survival curve: Horizontalization, verticalization and longevity extension”, Demography, 42(2):243-252.Google Scholar
  70. Choi, Y. H., Kim, J. H., Kim, D. K., et al. (2003) “Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians”, Journal of Gerontology: Medical Sciences, 58A(3):227-231.Google Scholar
  71. Christen, Y. (2003) “Les facteurs environnementaux de la long évit é ”, Presse Medicale, 32:370-376.Google Scholar
  72. Christensen, K., and Herskind, A. M. (2005) “Genetic factors associated with individual life duration: Heritability”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  73. Clarke, R. D. (1950) “A bio-acturial approach to forecasting rates of mortality”, In: Proceedings of the Centenary Assembly of the Institutes of Actuaries, Cambridge: Cambridge University Press, Vol. 2, pp. 12-27.Google Scholar
  74. Coale, A. J. (1996) “Age patterns and time sequence of mortality in national populations with the highest expectation of life at birth”, Population and Development Review, 22(1):127-135.Google Scholar
  75. Coles, L. S. (2001) “Table of world-wide living supercentenarians”, Journal of Anti-Aging Medicine, 4(3):267-269.Google Scholar
  76. Coles, L. S. (2004) “Demography of human supercentenarians”, Journal of Gerontology: Biological Sciences, 59A(6):579-586.Google Scholar
  77. Coley, D. M., Schlittler, D. L., Glickman, L. T., Hayeck, M., and Waters, D. J. (2003) “Exceptional longevity in pet dogs is accompanied by cancer resistance and delayed onset of major diseases”, Journal of Gerontology: Biological Sciences, 58A(12):1078-1084.Google Scholar
  78. Comfort, A. (1956) The Biology of Senescence. London: Routledge and Kegan Paul.Google Scholar
  79. Comfort, A. (1964) Aging: The Biology of Senescence. Austin, TX: Holt, Rinehart and Winston, Inc.Google Scholar
  80. Cournil, A., and Kirkwood, T. B. L. (2001) “If you would live long, choose your parents well”, Trends in Genetics, 17(5):233-235.Google Scholar
  81. Cournil, A., Legay, J-M., and Sch ächter, F. (2000) “Evidence of sex-linked effects on the inheritance of human longevity: A population-based study in the Valserine valley (French Jura), 18-20th centuries”, Philosophical Transactions of the Royal Society of London B. Biological Science, 267:1021-1025.Google Scholar
  82. Crimmins, E. M. (2004) “Trends in the health of the elderly”, Annual Review of Public Health, 25:79-98.Google Scholar
  83. Cutler, R. G. (1985) “La biologie du vieillissement et de la long évit é ”, Gerontologica Biomedica Acta, 1:7-61.Google Scholar
  84. D’Amico, M., Agozzino, E., Biagino, A., et al. (1999) “Ill-defined and multiple causes on death certificates-a study of misclassification in mortality statistics”, European Journal of Epidemiology, 15:141-8.Google Scholar
  85. De Moivre, A. (1756) The Doctrine of Chances. Third edition.Google Scholar
  86. Deevey, E. S. (1947) “Life tables for natural populations of animals”, The Quarterly Review of Biology, 22:283-314.Google Scholar
  87. D époid, F. (1973). “La mortalit é des grands vieillards”, Population, (4-5):755-792.Google Scholar
  88. Desjardins, B., and Charbonneau, H. (1990) “L’h éritabilit é de la long évit é ”, Population, 3:603-616.Google Scholar
  89. Desjardins, B. (1999) “Did Marie Louise Meilleur become the oldest person in the world?”. In: Jeune, B., Vaupel, J. W. (eds.), Validation of Exceptional Longevity. Odense: Odense University Press, pp. 189-194.Google Scholar
  90. Dewey, M. E., and Copeland, J. R. M. (2001) “Dementia in centenarians”, International Journal of Geriatric Psychiatry, 16:538-539.Google Scholar
  91. Doblhammer, G., and Vaupel, J. W. (2001) “Lifespan depends on month of birth”, Proceedings of the National Academy of Sciences of the United States of America, 98(5):2934-2939.Google Scholar
  92. Dublin, L. I. (1923) “The possibility of extending human life”, Metron, 3(2):175-197.Google Scholar
  93. Dublin, L. I., Kopf, E. W., and Lotka, J. A. (1926) “The components of death curves. An analysis of life table deaths by causes”, The American Journal of Hygiene, 7:S299-S333.Google Scholar
  94. Dublin, L. I., and Lotka, J. A. (1934) “The history of longevity in the United States”, Human Biology, 1.Google Scholar
  95. Dublin, L. I., and Lotka, J. A. (1945) “Trends in longevity”, The Annals of the American Academy, 5:123-134.Google Scholar
  96. Eakin, T., and Witten, M. (1995) “How square is the survival curve of a given species?”, Experimental Gerontology 30:33-64.Google Scholar
  97. Eichner, J. E., Dunn, S. T., Perveen, G., et al. (2002) “Apolipoprotein E polymorphism and cardiovascular disease: A HuGE review”, The American Journal of Epidemiology, 155(6):487-495.Google Scholar
  98. Evert, J., Lawler, E., Bogan, H., et al. (2003) “Morbidity profiles of centenarians: Survivors, delayers, and escapers”, Journal of Gerontology: Medical Sciences, 58A(3):232-237.Google Scholar
  99. Ewbank, D. C. (2004) “The APOE gene and differences in life expectancy in Europe”, Journal of Gerontology: Biological Sciences, 59A(1):16-20.Google Scholar
  100. Ewbank, D. C. (2005) “Mortality among the least frail: Lessons from research on the APOE gene”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  101. Faber, J. F. (1982) Life tables for the United States: 1900-2050. Actuarial Study, No. 87. SSA Publication No. 11-11534. Administration Office of Actuary.Google Scholar
  102. Faber, J. F., and Wade, A. H. (1983 ) Life Tables for the United States: 1900-2050. Actuarial Study, No. 89. SSA Publication No. 11-11536. Administration Office of Actuary.Google Scholar
  103. Ferrucci, L., Izmirlian, G., Leveille, S. G., et al. (1999) “Smoking, physical activity and active life expectancy”, American Journal of Epidemiology, 149:645-653.Google Scholar
  104. Fillenbaum, G. G., Blazer, D. G., Burcher, B. M., et al. (2002) “Apolipoprotein E ε4 and risk of mortality in African and white older community residents”, The Gerontologist, 42(3):381-386.Google Scholar
  105. Finch, C. E. (1998) “Variations senescence and longevity include the possibility of negligible senescence”, Journal of Gerontology: Series A Biological Science and Medical Science, 53:B235-B239.Google Scholar
  106. Finch, C. E., and Crimmins, E. M. (2004) “Inflammatory exposure and historical changes in Human life spans”, Science, 305:1736-1739.Google Scholar
  107. Finch, C. E., and Kirkwood, T. L. (2000) Chance, Development, and Aging. Oxford: Oxford University Press.Google Scholar
  108. Finch, C. E., and Pike, M. C. (1996) “Maximum life span predictions from the gompertz mortality model”, Journal of Gerontology: Biological Sciences, 51A(3):B183-B194.Google Scholar
  109. Finch, C. E., Tanzi, R. E. (1997) “Genetics of aging”, Science, 278:407-411.Google Scholar
  110. Fogata, M. L., Naik, P. N., and Goldberg, T. H. (1996) “Causes of death in the very old”, Journal of the American Geriatric Society, 44:1412-3.Google Scholar
  111. Fondation IPSEN (1991) 100 tableaux pour 100 ans. Fondation IPSEN. Paris: A la recherche du secrtet des centenaires, Document 1.Google Scholar
  112. Frederiksen, H., MCGue, M., Jeune, B., et al. (2002) “Do children of long-lived paprents age more successfully?”, Epidemiology, 13(3):334-339.Google Scholar
  113. Freudenberg, K. (1934) “Die Gesetzm ässigkeiten der menschilchen Lebensdauer. Ergebn. D”, Hygiene, 15:335-441.Google Scholar
  114. Fried, P. L., Tangen, C. M., Walston, J., et al. (2001) “Frailty in older adults: Evidence for a phenotype”, Journal of Gerontology: Series A Biological Sciences and Medical Sciences, 56A(3):M146-M156.Google Scholar
  115. Fries, J. F. (1980) “Aging, natural death, and the compression of morbidity”, The New England Journal of Medicine, 303(3):130-135.Google Scholar
  116. Fries, J. F. (1984) “The compression of morbidity: Miscellaneous comments about a theme”, The Gerontologist, 24:354-359.Google Scholar
  117. Fries, J. F. (1989) “The compression of morbidity: Near or far?”, Milbank Quarterly, 67(2):208-232.Google Scholar
  118. Fries, J. F. (2002) “Reducing disability in older age”, The Journal of the American Medical Association, 288(24):3164-3166.Google Scholar
  119. Fries, J. F., and Crapo, L. M. (1981) Vitality and Aging: Implication of the Rectangular Curve. San Francisco: W. H. Freeman and Company.Google Scholar
  120. Frisoni, G. B., Louhija, J., Geroldi, C., et al. (2001) “Longevity and the ε2 allele of Apolipoprotein E: The finnish centenarians study”, Journal of Gerontology: Medical Sciences, 56A(2):M75-M78.Google Scholar
  121. Gangemi, S., Basile, G., Alba, R., et al. (2003) “Increased circulating interleukin-18 levels in centenarians with no signs of vascular disease: Another paradox in longevity?”, Experimental Gerontology, 38:669-672.Google Scholar
  122. Gavrilov, L. A., and Gavrilova, N. S. (1997a) “When fatherhood should stop”, Science, 277:17-18.Google Scholar
  123. Gavrilov, L. A., and Gavrilova, N. S. (1997b) “Parental age at conception and offspring longevity”, Review in Clinical Gerontology, 7:5-12.Google Scholar
  124. Gavrilov, L. A., and Gavrilova, N. S. (1998). “The future of long life”, Science, 281(11):1611.Google Scholar
  125. Gavrilov, L. A., and Gavrilova, N. S. (2003) “The quest for a general theory of aging and longevity”, Science of Aging Knowledge Environment, www.sageke.sciencemag.org/cgi/content/full/sageke;2003/28/re5.
  126. Gavrilov, L. A., Gavrilova, N. S., Evdokushkina, G. N., Semyonova, V. G., Gavrilova, A. L., Evdokushkina, N. N., and Lapshin, E. V. (1996a) “Determinants of human longevity: Parental age at conception and offspring longevity”, Longevity Report, 10(54):7-15.Google Scholar
  127. Gavrilov, L. A., Gavrilova, N. S., Kroutko, V. N., Evdokushkina, G. N., Semyonova, V. G., Gavrilova, A. L., Lapshin, E. V., Evdokushkina, N. N., Kushnareva Yu, E., (1996b) “Specific decrease in longevity of daughters conceived by old fathers”, Longevity Report, 10(56):4-5.Google Scholar
  128. Gavrilov, L. A., Gavrilova, N. S., Kroutko, V. N., Evdokushkina, G. N., Semyonova, V. G., Gavrilova, A. L., Lapshin, E. V., Evdokushkina, N. N., and Kushnareva Yu, E., (1997) “Mutation load and human longevity”, Mutation Research, 377:61-62.Google Scholar
  129. Gavrilov, L. A., and Gavrilova, S. N. (1999) “Season of birth and human longevity”, Journal of Anti-aging Medicine, 2(4):365-366.Google Scholar
  130. Gavrilov, L. A., and Gavrilova, S. N. (2003) “Early-life factors modulating lifespan”. In: Rattan, S. I. S. (ed.), Modulating Aging and Longevity. Dordrecht: Kluwer Academic Publishers.Google Scholar
  131. Gavrilov, L. A., and Gavrilova, N. S. (2001a) “The reliability theory of aging and longevity”, Journal of Theoretical Biology, 213:527-545.Google Scholar
  132. Gavrilov, L.A., and Gavrilova, N. S. (2001b) “Biodemographic study of familial determinants of human longevity”, Population, 13(1):197-222.Google Scholar
  133. Gavrilova, N. S., Gavrilov, L. A., Evdokushkina, G. N., Semyonova, V. G., Gavrilova, A. L., Lapshin, E. V., Evdokushkina, N. N., Kushnareva Yu E., Kroutko, V. N., and Andreyev A Yu. (1998) “Evolution, mutations, and human longevity: European royal and noble families”, Human Biology, 70:799-804.Google Scholar
  134. Gavrilova, S. N., Gavrilov, L. A., Evdokushkina, G. N., et al. (2003) “Early-life predictors of human longevity: Analysis of the XIXth century birth cohorts”, Annales de d émographie historique, (2):177-198.Google Scholar
  135. Geesaman, B. J., Benson, E., Brewster, S. J., et al. (2003) “Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan”, Proceedings of the National Academy, 100(24):14115-14120.Google Scholar
  136. Go, C. G., Brustrom, J. E., Lynch, M. F., and Aldwin, C. M. (1995) “Ethnic trends in survival curves and mortality”, The Gerontologist, 35(3):318-326.Google Scholar
  137. Gompertz, B. (1825) “On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies”, Philosophical Transactions of the Royal Society of London B Biological Science, 115:513-585.Google Scholar
  138. Gordon, T. J. (1980) Changing Mortality Patterns. In the Future of Life Expectancy: Economic, Social and Medical Implications of Living Longer. Society of Actuaries, Chicago. Proceedings of a two-day symposium held March 10-11, 1980.Google Scholar
  139. Graunt, J. (1661) Observations Naturelles et Politiques R épertori ées dans l’Index ci-apr ès et faites sur les Bulletins de Mortalit é : Edition critique by E. Vilquin. Paris: INED.Google Scholar
  140. Greenwood, F. R. S. (1928) “ ‘Laws’of mortality from the biological point of view ”, Journal of Hygiene, XXVIII: 267-294.Google Scholar
  141. Greenwood, M., and Irwin. J. O. (1939) “The Biostatistics of senility”, Human Biology, 11(1):1-23.Google Scholar
  142. Grundy, E. (2005) “Marital status and family support of the oldest old in Great Britain”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.) Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  143. Gueresi, P., Troiano, L., Minicuci, N., et al. (2003) “The MALVA (MAntova LongeVA) study: An investigation on people 98 years of age and over in a province of Northern Italy”, Experimental Gerontology, 38:1189-1197.Google Scholar
  144. Gumbel, E. L. (1937) “La dur ée extr ême de la vie humaine”, Actualit és Scientifique et Industrielles 520, Paris: Statistique math ématique, Hermann et Cie Editeurs.Google Scholar
  145. Gurland, B. J., Page, W. F., and Plassman, B. L. (2004) “A twin study of the genetic contribution to age-related functional impairment”, Journal of Gerontology: Medical Sciences, 59A(8):859-863.Google Scholar
  146. Hagberg, B., Bauer, A. B., and Poon, L. W. (2001) “Cognitive functioning in centenarians: A coordinated analysis of results from three countries”, Journal of Gerontology: Psychological Sciences, 56B(3):P141-P151.Google Scholar
  147. Hayflick, L. (1981) “Prospects for human life extension by genetic manipulation”. In: Danon, D., Shock, N. W., Marois, M. (eds.), Aging: A Challenge to Science and Society, Vol. I. Oxford: Oxford University Press, pp. 162-179.Google Scholar
  148. Hayflick, L. (1996) How and Why we Age? New York: Ballantine Books.Google Scholar
  149. Hayflick, L. (2002) “Anarchy in gerontological terminology”, The Gerontologist, 42(3):416-421.Google Scholar
  150. Heiniger, M., and Wanders, A.C. (2002) Portrait d émographique de la Suisse. Berne: Office f éd éral de la statis-tique.Google Scholar
  151. Helle, S., Lummaa, V., and Jokela, J. (2002) “Sons reduced maternal longevity in preindustrial humans”, Science, 296:1085.Google Scholar
  152. Herskind, A. M., McGue, M. J., Holm, N. W., Sorense, T. I., Harvale, B., and Vaupel, J. W. (1996) “The heritability of Human Longevity: A population-based study of 2872 Danish Twin Pairs born 1870-1900”, Human Genetics, 97:319-323.Google Scholar
  153. Hill, G. B., (1993) “The entropy of the survival curve: An alternative measure”, Canadian Studies in Population 20(1): 43-57.Google Scholar
  154. Hill, M. E., Preston, S. H., and Rosenwaike, I. (2000) “Age reporting among white American aged 85 +: Results of a record linkage study”, Demography, 37(2):175-186.Google Scholar
  155. Hitt, R., Young-Xu, Y., Silver, M., and Perls, T. (1999) “Centenarians: The older you get, the healthier you have been”, The Lancet, 353:652.Google Scholar
  156. Hong Kong Census and Statistic Department. (2002) Hong Kong Life Tables 1996-2031. Hong Kong Government Printer.Google Scholar
  157. Horiuchi, S. (1991) “Assessing effects of mortality reduction on population aging”, Population Bulletin of the United Nations, 31:38-51.Google Scholar
  158. Horiuchi, S. (1997) “Postmenopausal acceleration of age-related mortality increase”, Journal of Gerontology, 52A(1):B78-B92.Google Scholar
  159. Horiuchi, S. (2000) “Greater lifetime expectations”, Nature, 405:744-745.Google Scholar
  160. Horiuchi, S. (2003) “Interspecies differences in the life span distribution: Humans versus invertebrates”. In: Carey, J. R., Shripad, T. (eds.), Population and Development Review, Vol. 29, pp. 127-151.Google Scholar
  161. Horiuchi, S. (2005) “Causes of death among the oldest-old: Age-related changes in the causes-of-death distribution”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  162. Horiuchi, S., and Wilmoth, J. R. (1997) “Age patterns of the life table aging rate for major causes of death in Japan, 1951-1990”, Journal of Gerontology, 52A(1):B67-B77.Google Scholar
  163. Horiuchi, S., and Wilmoth, J. R. (1998) “Deceleration in the age pattern of mortality at older ages”, Demography, 35(4):391-412.Google Scholar
  164. Hu, P., Reuben, D. B., Crimmins, E. M., Harris, T. B., Huang M-H., and Seeman, T. E. (2004) “The effect of serum Beta-Carotene concentration and burden of inflammation on all-cause mortality risk in hight-functioning older persons: Mac Arthur studies of successful aging”, Journal of Gerontology: Medical Sciences, 59A(8):849-854.Google Scholar
  165. Hubert, H. B., Bloch, D. A., Oehlert, J. W., and Fries, J. F. (2002) “Lifestyle habits and compression of morbidity”, Journal of Gerontology, 57A(6):M347-M351.Google Scholar
  166. Human Mortality Database. University of California, Berkeley (USA), and Max Planck Institute for Demo-graphic Research (Germany). Available at www.mortality.org or www.humanmortality.de (data downloaded on November 2004).
  167. Hyland, P., Duggan, O., and Turbitt, J. (2002) “Nonagenarians from the Swedish NONA immune study have increased plasma antioxidant capacity and similar levels of DNA damage in perpherical blood mononuclear cells compared to tounger control subjects”, Experimental Gerontology, 37:465-473.Google Scholar
  168. International Database on Longevity. Max Planck Institute for Demographic Research (Germany). Available at www.demogr.mpg.de/general/structure/division1/lab-sl/90.htm
  169. Ivanova, R., H énon, N., Lepage, V., et al. (1998) “HLA-DR alleles display sex-dependent effects on survival and discriminate between individual and familial longevity”, Human Molecular Genetics, 7:187-194.Google Scholar
  170. Jacquard, A. (1982) “Heritability of human longevity”. In: Preston, S. V. (ed.) Biological and Social Aspects of Mortality and the Length of Life. Li ège: Ordina Edition, pp. 303-313.Google Scholar
  171. Jansen, F., Nusselder, W. J., Looman, C. W. N., Mackenbach, J. P., and Kunst, A. E. (2003) “Stagnation in mortality decline among elders in the Netherlands”, The Gerontologist, 43(5):722-734.Google Scholar
  172. Jazwinski, S. M. (1996) “Longevity, genes and aging”, Science, 273:54-59.Google Scholar
  173. Jeune, B. (1995) “In search of the first centenarians”. In: Jeune, B., Vaupel, J. W. (eds.), Exceptional Longevity: From Prehistory to the Present. Odense: Odense University Press. (Odense Monographs on population Aging 2).Google Scholar
  174. Jeune, B. (2005) “Explanation of the decline in mortality among the oldest-old: A medical point of view”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  175. Jeune, B., and Skytthe, A. (2001) “Centenarians in Denmark in the past and the present”, Population, 13(1):75-94.Google Scholar
  176. Jeune, B., and Vaupel, J. W. (1999). Validation of Exceptional Longevity. Odense: Odense University Press.Google Scholar
  177. Jylha, M., and Luukkaala, T. (2005) “Social determinants of mortality in the oldest-old: Social class and the individual way of life”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  178. Kaeberlein, M., Jegalian, B., and McVey, M. (2002) “AGEID: A database of aging genes and interventions”, Mechanisms of Aging and Development, 123:1115-1119.Google Scholar
  179. Kannisto, V. (1988) “On the survival of centenarians and the span of life”, Population Studies, 42:389-406. Kannisto, V. (1991) “Frailty and survival”, Genus, 47(3-4):101-118.Google Scholar
  180. Kannisto, V. (1994) Development of Oldest-Old Mortality, 1950-1990: Evidence from 28 Developed Countries. (Odense Monographs on Population Aging 1) Odense: Odense University Press.Google Scholar
  181. Kannisto, V. (1996). The Advancing Frontier of Survival. Odense: Odense University Press.Google Scholar
  182. Kannisto, V. (1999) Measuring the Compression of Mortality. Paper distributed at European Population Conference, EAPS, IUSSP, NIDI, SN, NVD.Google Scholar
  183. Kannisto, V. (2000a). Central and Dispersion Indicators of Individual Life Duration: New Methods. International Union for the Scientific Study of Population, Seminar on Human Longevity, Individual Life Durations and Growth of the Oldest-Old, Montpellier, 23-26 October.Google Scholar
  184. Kannisto, V. (2000b) “Measuring the Compression of Mortality”, Demographic Research 3 (Article 6). http://www.demographic-research.org/Volumes/Vol3/6/
  185. Kannisto, V. (2001) “Mode and dispersion of the length of life”, Population, 13(1):159-171.Google Scholar
  186. Kannisto, V. (2005) “Central and dispersion indicators of individual life duration: New methods”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  187. Kannisto, V., Christensen, K., and Vaupel, J. W. (1997) “No increased mortality in later life for cohorts born during famine”, The American Journal of Epidemiology, 145(11):987-994.Google Scholar
  188. Kannisto, V., Lauristen, J., Thatcher, A. R., et al. (1994) “Reductions in mortality at advanced ages: Several decades of evidence from 27 countries”, Population and Development Review, 20:793-809.Google Scholar
  189. Kerber, R. A., O’Brien, E., and Smith, K. R. (2001) “Familial excess longevity in Utah genealogies”, Journal of Gerontology: Biomedical Sciences, 56A(3)B130-B139.Google Scholar
  190. Kestenbaum, B. M., and Fergusson, B. R. (2002) “Mortality of the extreme aged in the United States in the 1990s. Based on improved Medicare data”. North American Actuarial Journal, 6(3):38-44.Google Scholar
  191. Kirkwood, T. B. L. (1997) “Genetics and the future of human longevity”, Journal of the Royal College of Physicians of London, 31(6):669-673.Google Scholar
  192. Kirkwood, T. B. L., and Rose, M. R. (1991) “Evolution of senescence: Late survival sacrificed for reproduction”, Philosophical Transactions of the Royal Society of London B, 332:15-24.Google Scholar
  193. Kjoergaard, T. (1995) “Alleged Danish centenarians before 1800”. In: Jeune, B., Vaupel, J. W. (eds), Exceptional longevity: From Prehistory to the Present, Odense: Odense University Press. pp. 47-54.Google Scholar
  194. Koenig, R. (2001) “Sardinia’s mysterious male Methuselahs”, Science, 291(16):2074-2076.Google Scholar
  195. Kohn, R. R. (1982) “Cause of death in very old people”, Journal of the American Medical Association, 247:2793-2797.Google Scholar
  196. Kojima, T., Hidehiko, K., Aizu, T., Aria, Y., Takayama, M., Nakazawa, S., Ebihara, Y., Inagaki, H., Masui, Y., Gondo, Y., Sakaki, Y., and Hirose, N. (2004) “Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways”, Experimental Gerontology, 39:1595-1598.Google Scholar
  197. Kokaze, A., Ishikawa, M., Matsunaga, N., Yoshida, M., Sekine, Y., Sekiguchi, K., Satoh, M., Harada, M., Teruya, K., Takeda, N., Uchida, Y., Tsunoda, T., and Takashima, Y. (2003) “Longevity-associated mitochondrial DNA 5178 A/C polymorphism modulates effects of daily drinking and cigarette consumption on serum triglyceride levels in middle-aged Japanese men”, Experimental Gerontology, 38:1071-1076.Google Scholar
  198. Krach, C. A., and Velkoff, V. A. (1999) Centenarians in the United States. Washington, DC: US Department of Health and Human Services (Current Populations Reports, Special Studies).Google Scholar
  199. Kliegel, M., Moor, C., and Rott, C. (2004) “Cognitive status and development in the oldest old: A longi-tudinal analysis from the Heildelberg centenarain study”, Archives of Gerontology and Geriatrics, 39:143-156.Google Scholar
  200. Labat-Robert, J., Marques, M. A., and N’Doye, S. (2000) “Plasma fibronectine in French centenarians”, Archives of Gerontology and Geriatrics, 31:95-105.Google Scholar
  201. Laplace, P. S. (1812) Th éorie Analytique des Probabilit és. Paris: Veuve Courcier.Google Scholar
  202. Le Bourg, E., Thon, B., L égar é, J., Desjardins, B., and Charbonneau, H. (1993) “Reproductive life of FrenchCanadians in the 17-18th centuries: A search for a trade-off between early fecundity and longevity”, Experimental Gerontology, 28:217-232.Google Scholar
  203. Leslie, M. (2003) “Rising expectations”, Science of Aging Knowledge Environment, 47:ns 7.Google Scholar
  204. Levasseur, E. (1891) La population francaise, Tome II, Paris: Arthur Rousseau Editeur, pp. 143-184 (Chapter 13).Google Scholar
  205. Levy, M. L. (1996) “La rectangularization de la courbe des survivants”. In: AIDELF (ed.) Morbidit é , Mortalit é : Probl èmes de Mesure, Facteurs d’ évolution, Essai de Prospective. Paris: PUF, pp. 576-579.Google Scholar
  206. Lexis, W. (1878) “Sur la Dur ée Normale de la Vie Humaine et sur la Th éorie de la Stabilit é des Rapports Statistiques”, Annales de D émographie Internationale, 2(5):447-460.Google Scholar
  207. Lio, D., Pes, G. M., Carru, C., et al. (2003) “Association between the HLA-DR alleles and longevity: A study in Sardinian population”, Experimental Gerontology, 38:313-317.Google Scholar
  208. Ljungquist, B., Berg, S., Lanke, J., McClean, G., and Pedersen, N. L. (1998). “The effect of genetic factors for longevity: A comparaison of identical and fraternal twins in the Swedish Twin Registry”, Journal of Gerontology: Series A Biological Science and Medical Science, 53A:M441-M446.Google Scholar
  209. Lloyd-Jones, D. M., Martin, D. O., Larson, M. G., et al. (1998) “Accuracy of death certificates for coding coronary heart disease as the cause of death”, Annals of Internal Medicine, 129:1020-1026.Google Scholar
  210. Longo, V. D., and Finch, C. (2003) “Evolutionary medicine: From dwarf model systems to healthy centenarians?”, Science, 209:1342-1346.Google Scholar
  211. Louhija, J., Miettinen, H. E., Kontula, K., et al. (1994) “Ageing and genetic variation of plasma apolipoproteins. Relative loss of apolipoprotein E4 phenotype in centenarians”, Journal of Artherosclerosis and Thrombosis, 14:1084-1089.Google Scholar
  212. Ly, D. H., Lockhart, D. J., Lerner, R. A., et al. (2000) “Mitotic misregulation and human aging”, Science, 287:2486-2492.Google Scholar
  213. Lynch, S. M., and Brown, J. C. (2001) “Reconsidering mortality compression and deceleration: An alternative model of mortality rates”, Demography, 38:79-95.Google Scholar
  214. Magwere, T., Chapman, T., and Partridge, L. (2004) “Sex differences in the effect of dietary restriction on life span and mortality rates in female and male Drosophila Melanogaster”, Journal of Gerontology: Biological Sciences, 59A(1):3-9.Google Scholar
  215. Manton, K. G. (1991) “New biotechnologies and the limits to life expectancy”. In: Lutz, W. (ed.), Future demographic trends in Europe and North America. New York: Academic Press, pp. 97-115.Google Scholar
  216. Manton, K. G. (1999) “Dynamic paradigms for human mortality and aging”, Journal of Gerontology: Biological Sciences, 54A(6):B247-B254.Google Scholar
  217. Manton, K. G., and Singer, B. (1994) “What’s the fuss about the compression of mortality?”, Chance, 7:21-30.Google Scholar
  218. Manton, K. G., and Stallard, E. (1996) “Longevity in the United States: Age and sex-specific evidence on life span limits from mortality patterns 1960-1990”, Journal of Gerontology: Biological Sciences, 51A(5):B362-B375.Google Scholar
  219. Manton, K. G., and Tolley, H. D. (1991) “Rectangularization of the survival curve implications of an ill-posed question”, Journal of Aging and Health, 3(2):172-193.Google Scholar
  220. Manton, K. G., and Vaupel, J. W. (1995) “Survival after the Age of 80 in the United States, Sweden, France, England, and Japan”, New England Journal of Medicine, 333:1232-1235.Google Scholar
  221. Manton, K. G., Stallard, E., and Corder, L. (1999) “The limits og longevity and their implications for heath and mortality in developed countries”. In: Health and Mortality: Issues of Global Concern. New York: United Nations, pp. 324-343 (Chapter XIV).Google Scholar
  222. Marini, M., Lapalombella, R., Canaider, S., Farina, A., Monti, D., De Vescovi, V., Morellini, M., Bellizi, D., Dato, S., De Benedictis, G., Passarino, G., Moresi, R., Tesei, S., and Franceschi, C. (2004) “Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: A model to study the relevance of stress response in longevity”, Experimental Gerontology, 39:83-90.Google Scholar
  223. Martel, S., and Bourbeau, R. (2003) “Compression de la Mortalit é et Rectangularisation de la Courbe de Survie au Qu ébec au Cours du XXe Si ècle”, Cahiers Qu éb écois de D émographie, 32(1):43-75.Google Scholar
  224. Martin, G. M. (1999) “Genes that modulate longevity and senescence”, In: Robine, J-M., et al. (eds.), The Paradoxes of Longevity. Berlin: Springer, pp. 11-21.Google Scholar
  225. Masternak, M. M., Al-Regaiey, K., Bonkowski, M. S., Panici, J., Sun, L., Wang, J., Przybylski, G. K., and Bartke, A. (2004) “Divergent effects of caloric restriction on gene expression in normal and long-lived mice”, Journal of Gerontology: Biological Sciences, 59A(8):784-788.Google Scholar
  226. Matthijs, K., Van de Putte, B., and Vlietinck, R. (2002) “The inheritance of longevity in a Flemish village (18th-20th Century)”, European Journal of Population, 18:59-81.Google Scholar
  227. Mattison, J. A., Lane, M. A., Roth, G. S., and Ingram, D. K. (2003) “Calorie restriction in rhesus monkeys”, Experimental Gerontology, 38:35-46.Google Scholar
  228. Mazess, R. B., and Forman, S. H. (1979) “Longevity and age exageration in Vilcabamba, Ecuador”, Journal of Gerontology, 34(1):94-98.Google Scholar
  229. McCormack, J. (2001) “The emerging face of centenarians in Australia”, Gerontology, 47(suppl 1):533-534.Google Scholar
  230. McGue, M. J., Vaupel, J. W., Holm, N., and Harvald, B. (1993) “Longevity is moderately heritable in a sample of danish twins born 1870-1880”, Journal of Gerontology, 48:B237-B244.Google Scholar
  231. McKeown, T. (1976) The modern rise of population. London: Edward Arnold.Google Scholar
  232. McKeown, T. (1979) The Role of Medicine: Dream, Mirage, or Nemesis. Princeton: Princeton University Press.Google Scholar
  233. Mecocci, P., Polidori, M. C., Troiano, L., et al. (2000) “Plasma antioxidants and longevity: A study on healthy centenarians”, Free Radical Biology and Medicine, 28(8):1243-1248.Google Scholar
  234. Meroni, P. L., Mari, D., Monti, D., Coppola, R., Capri, M., Salvioli, S., Tincani, A., Gerli, R., and Franceschi, C. (2004) “Anti-beta 2 glycoprotein I antibodies in centenarians”, Experimental Gerontology, 39:1459-1465.Google Scholar
  235. Mesl é, F. (2005) “Causes of death among the oldest-old: Validity and comparability”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  236. Mesl é, F., and Vallin, J. (2000a) Comment am éliorer la pr écision des tables de mortalit é aux grands âges: le cas de la France?—Paris, INED, p. 26. (Communication pr ésent ée au Colloque de l’AIDELF ”Vivre plus longtemps, avoir moins d’enfants, quelles implications ?”, Byblos, Liban).Google Scholar
  237. Mesl é, F., and Vallin, J. (2000b) “Transition sanitaire: Tendances et perspectives”, M édecine/Science, 16:1161-1171.Google Scholar
  238. Mesl é, F., and Vallin, J. (2002) “Increase in life expectancy and Concentration of ages at death”, In: Robine, J-M., et al. (eds.) Determining Health Expectancies. Chichester: John Wiley & sons, pp. 13-33.Google Scholar
  239. Mesl é, F., Vallin, J., and Robine, J-M. (2000) “Vivre plus de 110 ans en France”, G érontologie et Soci ét é , 94:101-120.Google Scholar
  240. Miller, R. A. (2001) “A position paper on longevity genes”, Sageke.sciencemag.org 9/vp6.Google Scholar
  241. Ministry of Health and Welfare. (1963-2003) Zenkoku koureisha meibo (A list of centenarians in Japan).Google Scholar
  242. Ministry of Health and Welfare (2003) Life tables for Japan 2002. Statistics and information department, Minister’s Secretariat, Ministry of Health, Labor and Welfare.Google Scholar
  243. Morel, M. F. (1991) “The care of children: The influence of medical innovation and medical institutions on infant mortality 1750-1914”. In: Schofield, R., Reher, D., Bideau, A. (eds.), The Decline of Mortality in Europe. Oxford: Clarendon Press, pp. 196-219.Google Scholar
  244. Mosley, W. H., and Chen, L. C. (1984) “An analytical framework for the study of child survival in developing countries”. In: Mosley, W. H., Chen, L. C. (eds.), Child Survival: Strategies for Research (Population and Development Review, A Supplement to Volume 10), New York: The Population Council, pp. 25-45.Google Scholar
  245. M ûller, H-G., Chiou, J. M., Carey, J. R., et al. (2002) “Fertility and life span: Late children enhance female longevity”, Journal of Gerontology: Biomedical Sciences, 57A(3):B202-B206.Google Scholar
  246. Myers, G., and Lamb, V. (1993) “Theoretical perspectives on healthy life expectancy”. In: Robine, J-M., Mathers, C. D., Bone, M. R., Romieu, I. (eds.), Calculation of Health Expectancies; Harmonization, Consensus Achieved and Future Perspectives. Montrouge: John Libbey Eurotext, pp. 109-119.Google Scholar
  247. Myers, G. C., and Manton, K. G. (1984a) “Compression of mortality: Myth or reality?”, The Gerontologist, 24(4): 346-353.Google Scholar
  248. Myers, G. C., and Manton, K. G. (1984b) “Recent changes in the U.S. age at death distribution: Further observations”, The Gerontologist, 24(6):572-575.Google Scholar
  249. Myers, G. C., Lamb, V. L., and Agree, E. M. (2002) “Patterns of disability change associated with the epidemiological transition”. In: Robine, J-M., et al. (eds.) Determining health expectancies. Chichester: John Wiley & sons. pp. 59-74.Google Scholar
  250. Myers, J. C. (1996) “Comparative mortality trends among older persons in developed countries”, In: Caselli, G., Lopez, A. D. (eds.), Health and Mortality among Elderly Populations. Oxford, UK: Clarendon Press, pp. 87-111.Google Scholar
  251. Myers, R. J. (1966) “Validity of centenarian data in the 1960 census”, Demography, 3:470-476.Google Scholar
  252. Myers, R. J., and Shudde, L. O. (1955) “Mortality experience of Union civil war veterans”, Transactions of Society of Actuaries, 7:63-68.Google Scholar
  253. Nagnur, D., (1986) “Rectangularization of the survival curve and entropy: The Canadian experience 1921-1981”, Canadian Studies in Population, 13:83-102.Google Scholar
  254. Nusselder, W. (1998) Compression or Expansion of Morbidity ? A Life-table Approach. Thesis, Erasmus University Rotterdam. Amsterdam: Thesis Publishers.Google Scholar
  255. Nusselder, W. (2005) “Recent trends in life expectancy and rectangularisation of the survival curve at advanced ages in the Netherlands”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  256. Nusselder, W. J., and Mackenbach, J. P. (1996) “The rectangularization of the survival curve in Netherlands, 1950-1992”, Gerontologist, 36:773-782.Google Scholar
  257. Nusselder, W. J., and Mackenbach, J. P. (1997) “Rectangularization of the survival curve in the Netherlands: An analysis of underlying causes of death”, Journal of Gerontology: Social Sciences, 52B(3):S145-S154.Google Scholar
  258. Nusselder, W. J., and Mackenbach, J. P. (2000) “Lack of improvement of life expectancy at advanced ages in the Netherlands”, International Journal of Epidemiology, 29:140-148Google Scholar
  259. Nusselder, W. J., Looman, C. W. N., Marang Van De Mheen, P. J., et al. (2000) “Smoking elimination produces compression of morbidity”, Journal of Epidemiology and Community Health, 54:566-574.Google Scholar
  260. Oeppen, J., and Vaupel, J. W. (2002) “Broken limits to life expectancy”, Science, 296:1029-1031.Google Scholar
  261. Olshansky, S. J., and Ault, A. B. (1986) “The fourth stage of the epidemiologic transition: The age of delayed degenerative diseases”, Milbank Quarterly, 64(3):355-391.Google Scholar
  262. Olshansky, S. J., and Carnes, B. A. (1994) “Demographic perspectives on human senescence”, Population and Development Review, 20:57-80.Google Scholar
  263. Olshansky, S. J., and Carnes, B. A. (1997) “Ever since Gompertz”, Demography, 34(1):1-15.Google Scholar
  264. Olshansky, S. J., and Carnes, B. A. (2002) “A biodemographic interpretation of life span”, Population and Development Review, 28(3): 501-513.Google Scholar
  265. Olshansky, S. J., Carnes, B. A., and Cassel, C. (1990) “In search of Methuselah: Estimating the upper limits to human longevity”, Science, 250:634-640.Google Scholar
  266. Olshansky, S. J., Carnes, B. A., and Butler, R. (2001b) “If humans were built to last”, Scientific American, 284(3):50-55.Google Scholar
  267. Olshansky, S. J., Carnes, B. A., and D ésesquelles, A. (2001a) “Prospects for human longevity”, Science, 291:1491-1492.Google Scholar
  268. Olshansky, S. J., Rudberg, M. A., Carnes, B. A., et al. (1991) “Trading off longer life for worsening health. The expansion of morbidity hypothesis”, Journal of Aging and Health, 3(2):194-216.Google Scholar
  269. Omran, A. R. (1971) “The epidemiologic transition: A theory of Epidemiology of population change”, The Milbank Memorial Fund Quarterly, 49:509-538.Google Scholar
  270. Paccaud, F., Sidoti Pinto, C., Marazzi, A., and Mili, J. (1998) “Age at death and rectangularization of the sur-vival curve: Trends in Switzerland, 1969-1994”, Journal of Epidemiology and Community Health, 52:412-415.Google Scholar
  271. Palacios, R. (2002) “The future of global ageing”, International Journal of Epidemiology, 31:786-791.Google Scholar
  272. Palmore, E. B. (1984) “Longevity in Abkhazia: A reevaluation”, The Gerontologist, 24(1):95-96.Google Scholar
  273. Palmore, E. B. (1987) “Some errors and irrelevancies in the debate over compression of morbidity”, Gerontologica Perspecta, 1:30-31.Google Scholar
  274. Paolisso, G., Manzella, D., Barbieri, M., et al. (1999b) “Baseline heart rate variability in healthy centenarians: Differences compared with aged subjects (>75 years old)”, Clinical Science, 97:579-584.Google Scholar
  275. Paolisso, G., Manzella, D., Rizzo, M. R., et al. (2000) “Effect s of glucose ingestion on cardiac autonomic nervous system in healthy centenarians”, European Journal of Clinical Investigation, 30:277-284.Google Scholar
  276. Paolisso, G., Tagliamonte, M. R., Rizzo, M. R., et al. (1999a) “Mean arterial blood pressure and serum levels on the molar ratio of insulin-likes growth factor-1 to its binding proteine-3 in healthy centenarians”, Journal of Hypertension, 17:67-73.Google Scholar
  277. Pearl, R. (1931) “Studies on human longevity. IV. The inheritance of longevity. Preliminary report”, Human Biology, 3:245-269.Google Scholar
  278. Pearl, R., and Doering, C. R. (1923) “A comparison of the mortality of certain lower organisms with that of man”, Science, 1468:209-212.Google Scholar
  279. Pearl, R., and Miner, J. R. (1935) “Experimental studies on the duration of life. XIV the comparative mortality of certain lower organisms”, The Quarterly Review of Biology, 10:60-79.Google Scholar
  280. Pearson, K. (1902) “On the modal value of an organ or character”, Biometrika, 1(2):260-261.Google Scholar
  281. Pelletier, F., Legare, J., and Bourbeau, R. (1997) “Mortality in Quebec during the nineteenth century: From the state to the cities”, Population Studies, 51:93-103.Google Scholar
  282. Perks, W. (1932) “On some experiments on the graduation of mortality statistics”, Journal of the Institute of Actuaries, 63:12-40.Google Scholar
  283. Perls, T. (2001) “Genetic and phenotypic markers among centenarians”, Journal of Gerontology: Medical Sciences, 56A(2):M67-M70.Google Scholar
  284. Perls, T. (2003) “Genetics of exceptional longevity”, Experimental Gerontology, 38:725-730.Google Scholar
  285. Perls, T. (2004) “Dementia-free centenarians”, Experimental Gerontology, 39:1587-1593.Google Scholar
  286. Perls, T., Kunkel, L., and Puca, A. (2002) “The genetics of exceptional human longevity”, Journal of the American Geriatrics Society, 50:359-368.Google Scholar
  287. Perls, T., Terry, D. F., Silver, M., et al. (2000) “Centenarians and the genetics of longevity”, Results and Problems in Cell Differentiations, 29:1-20.Google Scholar
  288. Perls, T., Wilmoth, J., Levenson, R., et al. (2002) “Life-long sustained mortality advantage of siblings of cen-tenarians”, Proceedings of the National Academy of Sciences of the United States of America, 99(12):8442-8447.Google Scholar
  289. Perls, T. T., Bubrick, E., Wager, C. G., Vijg, J., and Kruglyak, L. (1998a). “Siblings of centenarians live longer”, Lancet, 351:1560.Google Scholar
  290. Perls, T. T., Alpert, L., and Fretts, R. C. (1998b) “Middle-aged mothers live longer”, Nature, 389:133 (Scientific correspondence).Google Scholar
  291. Perls, T. T., Bochen, K., Freeman, N., et al. (1999) “Validity of reported age and centenarian prevalence in a New England sample”, Age and Ageing, 28:193-197.Google Scholar
  292. Perozzo, L. (1879) “Distribuzione dei morti per eta”, Annali di Statistica, 2nd series, 5:75-93.Google Scholar
  293. Philippe, P. (1980) “Longevity: Some familial correlates”, Social Biology, 27(3):211-219.Google Scholar
  294. Phillips, W. (1935) “A basic curve of death”, Journal of the Institute of Actuaries, 80:S289-S325.Google Scholar
  295. Poulain, M., Chambre, D., and Foulon, M. (2001) “Survival among Belgian centenarians (1870-1894 cohorts)”, Population, 13:117-38.Google Scholar
  296. Poulain, M., Pes, G. M., Grasland, C., Carru, C., Ferrucci, L., Baggio, G., Franceschi, C., and Deiana, L. (2004) “Identification of a geographic area characterized by extreme longevity in the Sardinia island: The AKEA study”, Experimental Gerontology, 39:1423-1429.Google Scholar
  297. Poulain, M., Pes, G., Carru, C., Ferrucci, L., Baggio, G., Franceschi, C., and Deiana, L. (2005) “The validation of exceptional male longevity in Sardinia”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  298. Preston, S. H. (1975) “The changing relation between mortality and level of economic development”, Population Studies, 29:231-48.Google Scholar
  299. Preston, S. H. (1992) “Cohort succession and the future of the oldest old”. In: Suzman, R. M., Willis, D. P., Manton, K. G. (eds.), The Oldest-Old. Oxford: Oxford University Press, pp. 50-57.Google Scholar
  300. Preston, S. H., Elo, I. T., and Stewart, Q. (1999) “Effects of age misreporting on mortality estimates at older ages”, Population Studies, 53:165-177.Google Scholar
  301. Promislow, D. E. L. (1998) “Longevity and the barren aristocrat”, Nature, 396:719-720.Google Scholar
  302. Puca, A. A., Daly, M. J., Brewster, S. J., Matisse, T. C., Barret, J., Shea-Drinkwater, M., Kang, S., Joyce, E., Nicoli, J., Benson, E., Kunkel, L. M., and Perls, T. (2001) “A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4”, Proceedings of the National Academy of Sciences of the United States of America, 98(18):10505-10508.Google Scholar
  303. Quetelet, A. (1835) Sur l’homme et le d éveloppement de ses facult és, essai d’une physique sociale. Pairs: Bachelier; reprint paris: Fayard, 1991.Google Scholar
  304. Quetelet, A. (1848) Du syst éme social et des lois qui le r égissent. Pairs: Guillaumin, Book 1.Google Scholar
  305. Quetelet, A. (1871) Anthropom étrie ou mesure des diff érentes facult és de l’homme. Brussels: Muquardt.Google Scholar
  306. Rabini, R. A., Moretti, N., and Staffolani, R. (2002) “Reduced susceptibility to peroxidation of erythrocyte plasma membranes from centenarians”, Experimental Gerontology, 37:457-663.Google Scholar
  307. Reed, T., Carmelli, D., Robinson, T. S., et al. (2003) “More favourable midlife cardiovascular risk factor levels in male twins and mortality after 25 years of follow-up is related to longevity of their parents”, Journal of Gerontology: Medical Sciences, 58A(5):425-431.Google Scholar
  308. Riley, J. C. (1990) “The risk of being sick: Morbidity trends in four countries”, Population and Development Review, 16(3):403-432.Google Scholar
  309. Riley, J. C. (2001) Rising Life Expectancy: A Global History. Cambridge: Cambridge University Press.Google Scholar
  310. Ritchie, K. (1995) “Mental status examination of an exceptional case of longevity J.C. aged 118 years”, British Journal of Psychiatry, 166:229-235.Google Scholar
  311. Robine, J.-M. (2001) “A new biodemographic model to explain the trajectory of mortality”, Experimental Gerontology, 36,899-914.Google Scholar
  312. Robine, J.-M. (2001) “Redefining the stages of the epidemiological transition by a study of the dispersion of life spans: The case of France”, Population”, 13(1):173-194.Google Scholar
  313. Robine, J.-M. (2003) “Life course, environmental change, and life span”, Population and Development Review, 29:229-38.Google Scholar
  314. Robine, J.-M., and Allard, M. (1998) “The oldest human”, Science, 279:1834-1835.Google Scholar
  315. Robine, J.-M., and Allard, M. (1999) “Jeanne Calment: Validation of the duration of her life”. In: Jeune, B., Vaupel, J. W. (eds.) Validation of Exceptional Longevity. (Odense Monographs on Population Aging 6) Odense: Odense University Press, pp. 145-172.Google Scholar
  316. Robine, J.-M., Cournil, A., Henon, N., and Allard, M. (2003d) “Have centenarians had parents younger than the others”, Experimental Gerontology, 38:361-365.Google Scholar
  317. Robine, J.-M., and Jagger, C. (2002) “What do we know about the cognitive status of centenarians”, In: Finch, C., Robine, J.-M., Christen, Y. (eds.), Brain and Longevity. Berlin: Springer, pp. 145-152.Google Scholar
  318. Robine, J.-M., Jagger, C., Mathers, C. D., Crimmins, E. M., and Suzman, R. M. (2003c) Determining health expectancies. Chichester: Willey.Google Scholar
  319. Robine, J.-M., and Michel, J. P. (2004) “Looking forward for a general theory on population aging”, Journal of Gerontology: Medical Sciences, 59A(6):590-597.Google Scholar
  320. Robine, J.-M., Paccaud, F. (2005) “Nonagenarians and centenarians in Switzerland, 1860-2001: A demographic analysis”, Journal of Epidemiology and Community Health, 59:31-37.Google Scholar
  321. Robine, J.-M., Romieu, I., and Allard, M. (2003b) “Les centenaires fran çais et leur état de sant é fonctionnelle”, La Presse M édicale, 33:360-364.Google Scholar
  322. Robine, J.-M., and Saito, Y. (2003) “Survival beyond age 100: The case of Japan”, Population and Development Review, 29:208-28.Google Scholar
  323. Robine, J.-M., Saito, Y., and Jagger, C. (2003a) “The emergence of extremely old people: The case of Japan”, Experimental Gerontology, 38:735-739.Google Scholar
  324. Robine, J.-M., and Vaupel, J. W. (2001) “Supercentenarians: Slower ageing individuals or senile elderly?”, Experimental Gerontology, 36:915-930.Google Scholar
  325. Robine, J.-M., and Vaupel, J. W. (2002) “Emergence of supercentenarians in low-mortality countries”, North American Actuarial Journal, 6(3):54-63.Google Scholar
  326. Robine, J.-M.,Caselli, G., et al. (2005). “An unprecedented increase in the number of centenarians”, Genus, LX l(1):57-82.Google Scholar
  327. Rose, G., Dato, S., Altomare, K., et al. (2003) “Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in elderly”, Experimental Gerontology, 38:1065-1070.Google Scholar
  328. Rosenwaike, I., and Stone, L. F. (2003) “Verification of the ages of supercentenarians in the United States: Results of a matching study”, Demography, 40(4):727-739.Google Scholar
  329. Rothenberg, R., Lentzner, H. R., and Parker, R. A. (1991) “Population aging patterns: The expansion of mortality”, Journal of Gerontology, 46:S66-S70.Google Scholar
  330. Samuelsson, G., and Johnson, A. M. (2001) “Centenarians in France, Georgia, Hungary and Sweden: Social characteristics”, Indian Journal of Gerontology, 15(1-2):29-52.Google Scholar
  331. Savarino, L., Grandi, D., Ciapetti, G., et al. (2001) “Serum concentrations of zinc and selenium in elderly: Results in healthy nonagenarians and centenarians”, Experimental Gerontology, 36:327-339.Google Scholar
  332. Sch ächter, F., Faure-Delanef, L., Guenot, F., et al. (1994) “Genetic association with human longevity at APOE and ACE loci”, Nature Genetics, 6:29-32.Google Scholar
  333. Schneider, E. R. L., and Brody, J. A. (1983) “Aging, natural death, and the compression of morbidity: Another view”, The New England Journal of Medicine, 304(14):854-855.Google Scholar
  334. Silver, M. H., Jilinskaia, E., and Perls, T. T. (2001) “Cognitive functional status of age-confirmed centenarians in a population-based study”, Journal of Gerontology: Psychosocial Sciences, 56B(3):P134-P140.Google Scholar
  335. Simar, D., Malatesta, D., Koechlin, C., Cristol, J. P., Vendrell, J. P., and Caillaud, C. (2004) “Effect of age on Hsp72 expression in leucocytes of healthy active people”, Experimental Gerontology, 39:1467-1474.Google Scholar
  336. Silverman, J. M., Smith, C. J., and Marin, D. B. (1999) “Identijying families with likely protective factors against Alzheimer disease”, American Journal of Human Genetics, 64:832-838.Google Scholar
  337. Skytthe, A., and Jeune, B. (1995) “Danish centenarians after 1800”. In: Jeune, B., Vaupel, J. W. (eds.), Exceptional longevity: From Prehistory to the Present. Odense: Odense University Press (Monographs on population Aging 2).Google Scholar
  338. Smith, D. W. E. (1993) Human Longevity. New York, NY: Oxford University Press.Google Scholar
  339. Smith, D. W. E. (1994) “The tails of survival curves”, BioEssays, 16(12):907-911.Google Scholar
  340. Smith, D. W. E. (1997) “Centenarians: Human longevity outliers”, The Gerontologist, 37(2):200-207.Google Scholar
  341. Strehler, B. L. (1975) “Implications of aging research for society”. In: Theoretical Concepts of Developmental and Age Changes. Federation Proceedings, 34(1):5-8.Google Scholar
  342. Takata, H., Suzuki, M., Ishii, T., et al. (1987) “Influence of major histocompatibility complex region genes on human longevity among Okinawan-Japanese centenarians and nonagenarians”, The Lancet, 10:824-826.Google Scholar
  343. Takuto, K., Izumiyama-Shimomura, Honma, N., et al. (2002) “Telomere lengths are characteristic in each human individual”, Experimental Gerontology, 37:523-531.Google Scholar
  344. Tan, Q., Yashin, A. I., Bladbjerg, E. M., et al. (2002) “A case-only approach for assessing gene by sex interaction in Human longevity”, Journal of Gerontology: Biological Sciences, 57A(4):B129-B133.Google Scholar
  345. Tanaka, M., Gong, J. S., Zhang, J., et al. (1998) “Mitochondrial genotype associated with longevity”, Lancet, 351:185-186 (Research letter).Google Scholar
  346. Tauchi, H., Sato, T., and Watanabe, T. (1999) Japanese Centenarians. Institute for Medical Science of Aging, Aichi: Aichi Medical University.Google Scholar
  347. Terry, D. F., Wilcox, M., MCCormick, M. A., et al. (2003) “Cardiovascular advantages among the offspring of centenarians”, Journal of Gerontology: Medical Sciences, 58A(4):367-371.Google Scholar
  348. Terry, D. F., Wilcox, M., MCCormick, M. A., et al. (2004) “Cardiovascular delay in centenarian offspring”, Journal of Gerontology: Medical Sciences, 59A(4):385-389.Google Scholar
  349. Thatcher, A. R. (1992) “Trends in numbers and mortality at high ages in England and Wales”, Population Studies, 46:411-426.Google Scholar
  350. Thatcher, R. (1997) “Trends and prospects at very high ages”. In: Charlton, J., Murphy, M. (eds.), The Health of Adult Britain 1841-1994. London: The Stationery Office (Vol 1 and 2).Google Scholar
  351. Thatcher, A. R. (1999a) “The demography of centenarians in England and Wales”, Population Trends, 162 (Part1):5-43.Google Scholar
  352. Thatcher, A. R. (1999b). “The long-term pattern of adult mortality and the highest attained age”, Journal of the Royal Statistical Society Series A, A 162, 5-43.Google Scholar
  353. Thatcher, A. R. (1999c) “Katherine Plunket: A well documented supercentenarian in 1930”. In: Jeune, B., Vaupel, J. W. (eds.), Validation of Exceptional Longevity. Odense: Odense University Press, pp. 135-138.Google Scholar
  354. Thatcher, A. R. (2001) “The demography of centenarians in England and Wales”, Population, 13:139-156.Google Scholar
  355. Thatcher, A. R., Kannisto, V., and Vaupel, J. W. (1998) The Force of Mortality at Ages 80 to 120. Odense: Odense University Press.Google Scholar
  356. Thatcher, R. V., Kannisto, V., and Andreev, K. (2002). “The survivor ratio method for estimating numbers at high ages”, Demographic Research, 6(1):1-12. (Available online at www.demographic-research.org).
  357. Thiele, T. N. (1871) “On a mathematical formula to express the rate of mortality throughout the whole of life, tested by a series of observations made use of by the Danish life insurance company of 1871”, Journal of the Institute of Actuaries and Assurance Magazine, XVI:S313-S329.Google Scholar
  358. Thoms, W. J. (1873) Human longevity. London: John Murray.Google Scholar
  359. Tuljapurkar, S., Li, N., and Boe, C. (2000) “A universal pattern of mortality decline in the G7 countries”, Nature, 405:789-792.Google Scholar
  360. Tyner, S. D., Venkatachalam, S., Chol, J. et al. (2002) “p53 mutant mice that display early ageing-associated phenotypes”, Nature, 415(3):45-53.Google Scholar
  361. Vallin, J. (1992) “Quelles hypoth èses peut-on faire sur l’ évolution future de la mortalit é ”. In: Tapinos, G. (ed.), La France dans deux g én érations: Population et soci ét é dans le premier tiers du XXI i ème si ècle. Paris: Arth ème Fayard.Google Scholar
  362. Vallin, J. (1993) “Future of health expectancy”. In: Robine, J-M., et al. (eds.), Calculation of Health Expectancies, Harmonization, Consensus Achieved and Future Perspectives. Montrouge: John Libbey.Google Scholar
  363. Vallin, J. (2005) “Mortality differences by sex among the oldest-old”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  364. Vallin, J., and Berlinguer, G. (2002). “De la mortalit é endog ène aux limities de la vie”. In: D émographie: analyse et synth èse III. Les d éterminants de la mortalit é . (Chapter 48).Google Scholar
  365. Vallin, J., and Caselli, G. (1997) “Toward a new horizon in demographic trends: The combined effects of 150 years life expectancy and new fertility models”. In: Robine, J-M., Vaupel, J. W., Jeune, B., Allard, M. (eds.), Longevity: To the Limits and Beyond. Berlin: Springer.Google Scholar
  366. Vallin, J., and Mesl é, F. (2001) “Vivre au-del à de 100 ans”, Population et Soci ét é , 365:4.Google Scholar
  367. Van Den Biggelaar, A. H. J., Huizinga, T. W. J., De Craen, A. J. M., Gussekloo, J., Heijmans, B. T., Fr ölich, M., and Westendorp, R. G. J. (2004) “Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study”, Experimental Gerontology, 39:1407-1414.Google Scholar
  368. Vandenbroucke, J. P. (1998) “Maternal inheritance of longevity”, Lancet, 351:1064 (Correspondence).Google Scholar
  369. Vanfleteren, J. R., De Vreese, A., and Braeckman, P. (1998). “Two-parameter logistic and Weibul equations provide better fits to survival data from isogenic population of Caenorhabditis elegans in axenic culture than does the Gompertz model”, Journal of Gerontology: Series A Biological Science and Medical Science, 53A:B393-B403.Google Scholar
  370. Vaupel, J. W. (2002) “Life expectancy at current rates vs current conditions: A reflexion stimulated by Boogaarts and Feeney’s ‘How long do we live?”’, Demographic Research, 7(8):365-378.Google Scholar
  371. Vaupel, J. W. (2002) “Post-Darwinian Longevity. MPIDR Working Paper WP 2002-043 September”, Demographic Research. http://www.demogr.mpg.de
  372. Vaupel, J. W., and Jeune, B. (1995) “The emergence and proliferation of centenarians”. In: Jeune, B., Vaupel, J. W. (eds.), Exceptional Longevity: From Prehistory to the Present. Odense: Odense University Press (Monographs on population Aging 2).Google Scholar
  373. Vaupel, J. W., and Lundstrom, H. (1994) “The future of mortality at older ages in developed countries”. In: Lutz, W. (ed.), The Future Population of the World: What Can We Assume Today? London, UK: Earthscan Publications, pp. 295-315.Google Scholar
  374. Vaupel, J. W., Manton, K. G., and Stallard, E. (1979) “The impact of heterogeneity in individual frailty on the dynamics of mortality”, Demography, 16:439-454.Google Scholar
  375. Vaupel, J. W., Carey, J. R., Christensen, K., Johnson, T. E., Yashin, A. I., Holm, N. V., Iachine, I. A., Kannisto, V., Khazaeli, A. A., Liedo, P., Longo, V. D., Zeng, Yi., Manton, K. G., and Curtsinger, J. W. (1998) “Biodemographic trajectories of longevity”, Science, 280:855-860.Google Scholar
  376. Vaupel, J. W., et al. (2003) “Aging. It’s never too late”, Science, 301(5640):1679-1681.Google Scholar
  377. V éron, J., and Rohrbasser, J. M. (2003) “Wilhelm lexis: The normal length of life as an expression of the ‘nature of things”, Population, 58(3):303-322.Google Scholar
  378. Vincent, P. (1951) “La mortalit é des vieillards”, Population, 6:181-204.Google Scholar
  379. Vita, A. J., Terry, R. B., Hubert, H. B., and Fries, J. F. (1998) “Aging, health risks, and cumulative disability”, New England Journal of Medicine, 338:1035-1041.Google Scholar
  380. Walford, R. (1985) Maximum Life Span. New York: WW Norton & Company.Google Scholar
  381. Wang, Z. (2001) Age Validation, Demographic Characteristics and Functional Status among Chinese Centenarians. Dissertation, University of Southern Denmark, Faculty of Health Sciences.Google Scholar
  382. Wang, Z., Yi, Z., Jeune, B., and Vaupel, J. W. (1997) “A demographic and health profile of centenarians in China”. In: Robine, J-M., et al. (eds.), Longevity : To the Limits and Beyond. Berlin, Springer-Verlag.Google Scholar
  383. Wang, Z., Yi, Z., Jeune, B., and Vaupel, J. W. (1998) “Age validation of Han Chinese centenarians”, Genus, 54(1-2):123-141.Google Scholar
  384. Weitz, J. S., and Fraser, H. B. (2001) “Explaining mortality rate plateaus”, Proceedings of the National Academy of Sciences of the United States of America, 98(26):15383-15386.Google Scholar
  385. Westendorp, R. G., and Kirkwood, T. B. L. (1999) “Human longevity at the cost of reproductive success”, Nature, 396:743-746.Google Scholar
  386. Westendorp, R. G., and Kirkwood, T. B. L. (2001) “Maternal and paternal lines of familial longevity”, Population, 13(1):223-236.Google Scholar
  387. White, K. M. (2002) “Longevity advances in high-income countries, 1955-1996”, Population and Development Review, 2002;28:59-76.Google Scholar
  388. Wick, G., Berger, P., Jansen-D ürr, P., et al. (2003) “A Darwinian-evolutionary concept of age-related diseases”, Experimental Gerontology, 38:13-25.Google Scholar
  389. Wigzell, F. W. (1970) “The functional state of nonagenarians”, Geriatrics, 170-178.Google Scholar
  390. Williams, G. C. (1957) “Pleiotropy, natural selection, and the evolution of senescence”, Evolution, 11:398-411.Google Scholar
  391. Wilmoth, J. R. (1995) “Are mortality rates falling at extremely high ages? an investigation based on a model proposed by Coale and Kisker”, Population Studies, 49:281-295.Google Scholar
  392. Wilmoth, J. R. (1997) “In search of limits: What do demographic trends suggest about the future of human longevity”. In: Kenneth, W. W., Caleb, E. F. (eds.), Between Zeus and the Salmon: The Biodemography of Longevity. Washington, DC: National Academy Press, pp. 38-64.Google Scholar
  393. Wilmoth, J. R. (1998a) “Is the pace of Japanese mortality decline converging toward international trends?”, Population and Development Review, 24(3):593-600.Google Scholar
  394. Wilmoth, J. R. (1998b) “The future of human longevity: A demographer’s perspective”, Science, 280:395-397.Google Scholar
  395. Wilmoth, J. R. (2000) “Demography of longevity: Past, present, and future trends”, Experimental Gerontology, 35(9-10):1111-1129.Google Scholar
  396. Wilmoth, J. R. (2001) “How long can we live? A review essay”, Population and Development Review, 27:791-800.Google Scholar
  397. Wilmoth, J. R. (2002) “Human longevity in historical perspective”. In: Paola, S. T. (ed.), Physiological Basis of Aging and Geriatrics, 3rd edition, Boca Raton, FL: CRC Press, pp. 11-24.Google Scholar
  398. Wilmoth, J. R., and Dennis, M. (2005) “Social differences in older adult mortality in the United States: Questions, data, methods, and results”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  399. Wilmoth, J. R., and Lundstr öm, H. (1996) “Extreme longevity in five countries: Presentation of trends with special attention to issues of data quality”. European Journal of Population, 12:63-93.Google Scholar
  400. Wilmoth, J. R., and Horiuchi, S. (1999) “Rectangularization revisited: Variability of age at death within human populations”, Demography, 36(4):475-495.Google Scholar
  401. Wilmoth, J. R., and Robine, J.-M. (2003) “The world trend in maximum life span”, Population and Development Review, 29:239-257.Google Scholar
  402. Wilmoth J. R., Skytthe, A., Friou, D., and Jeune, B. (1996) “The oldest man ever? A case study of exceptional longevity”, Gerontologist, 36:783-788.Google Scholar
  403. Wilmoth, J. R., Deegan, L. J., Lundstro, H., et al. (2000) “Increase of maximum life-span in Sweden, 1861-1999”, Science, 289:2367-2368.Google Scholar
  404. Yashin, A. I., et al. (2001) “The new trends in survival improvement require a revision of traditional gerontological concepts”, Experimental Gerontology, 37:157-167.Google Scholar
  405. Yashin, A. I., De Benedictis, G., Vaupel, J. W., et al. (1999) “Genes, demography, and life span: The contribution of demographic data in genetic studies on aging and longevity”, American Journal of Human Genetics, 65:1178-1193.Google Scholar
  406. Yashin, A. I., De Benedictis, G., Vaupel, J. W., et al. (2000) “Genes and longevity: Lessons from studies of centenarians”, Journal of Gerontology: Biological Sciences, 55A(7):B319-B328.Google Scholar
  407. Zeng, Y., and Vaupel, J. (2005) “Oldest old mortality in China”. In: Robine, J-M., Crimmins, E., Kannisto, V., Carri ère, Y. (eds.), Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population. Berlin: Springer.Google Scholar
  408. Zeng, Y., Vaupel, J. W., Xiao, Z., et al. (2001) “The healthy longevity survey and the active life expectancy of the oldest old in China”, Population, 13(1):95-116.Google Scholar
  409. Zuliani, G., Cherubini, A., and Volpato, S. (2002) “Genetic factors associated with the absence of atherosclerosis in octogenarians”, Journal of Gerontology: Medical Sciences, 57A(9):M611-M615.Google Scholar

Copyright information

© Springer 2007

Authors and Affiliations

  • Jean-Marie Robine
    • 1
  1. 1.University of MontpellierFrance

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