The spread of solid cancers beyond the confinements of their tissue compartment into other parts of the same tissue and successively into neighboring tissues (invasion) and distant organs (metastasis) is the defining property of malignancy. Invasion and metastasis are decisive for the clinical course of most cancers.
KeywordsStromal Cell Hyaluronic Acid Tumor Stroma Lymph Vessel Metastasis Suppressor Gene
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