Apoptosis and Replicative Senescence in Cancer

In normal tissues, cell proliferation is limited by terminal differentiation and counterbalanced by cell loss, often via apoptosis. Cell damage also elicits apoptosis or necrosis. Moroever, apoptosis can be induced in response to inappropriate proliferation or by cytotoxic immune cells.


Telomere Length Death Receptor Mitochondrial Permeability Transition Intrinsic Pathway Extrinsic Pathway 
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Copyright information

© Springer 2007

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