Effect of 3′, 5′-Cyclic Amp on Gene Expression in Escherichia Coli

  • D. Schlessinger
  • Y. Ohnishi
  • M. Kuwano
  • L. Silengo
Chapter
Part of the Biological Council book series (BCSDA)

Abstract

The disparity between the known roles of cyclic AMP (cAMP) in bacteria and higher cells has been puzzling. In mammalian cells, as participants of this Symposium have been reminding us, a number of effects are exerted independent of the transcription process, presumably by activating latent enzymatic machinery-or possibly latent messenger RNA. In contrast, for the best characterized systems in bacteria, cyclic AMP helps to determine the repertoire of gene transcription open to the cell [1–5].

mRNA

messenger RNA

cAMP

3′,5′ cyclic AMP.

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Copyright information

© Institute of Biology Endowment Fund 1971

Authors and Affiliations

  • D. Schlessinger
    • 1
  • Y. Ohnishi
    • 1
  • M. Kuwano
    • 1
  • L. Silengo
    • 1
  1. 1.Department of MicrobiologyWashington University School of MedicineSt. LouisUSA

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