Traumatic Brain Injury pp 223-244 | Cite as
Behavioral and Psychiatric Comorbidities of TBI
Abstract
Traumatic brain injury (TBI) is associated with a variety of behavioral consequences, including symptoms of depression, anxiety, aggression, and impulse control and overlaps with many of the symptoms of post-traumatic stress and post-traumatic stress disorder. There are many challenges to researchers and clinicians, including heterogeneity of the injury, distinguishing premorbid characteristics from the consequences of the TBI, lack of specificity in diagnostic criteria, and the absence of systematic therapeutic trials. In this chapter, we present an overview of the literature on psychiatric and behavioral consequences of TBI, highlighting those studies that investigate the incidence of these conditions, contribution of premorbid functioning to subsequent symptoms, and characteristics of mild TBI (frequently referred to as concussion) that provide clues to distinguishing it from other psychiatric comorbidities. Our analysis of the available literature suggests that in some, but not all cases, TBI may diminish inhibitory control over certain behaviors while in others, there may be an exacerbation of clinical expression of psychiatric symptoms. Treatment needs to consider whether there is a unique sensitivity to adverse events in patients who have suffered a TBI and prospective trials should be encouraged.
Keywords
Impulsive aggression Post-concussion syndrome Suicide Post-traumatic stress disorder Depression Traumatic brain injury Military Veteran AggressionReferences
- Adler AB, Bliese PD, McGurk D, Hoge CW, Castro CA. Battlemind debriefing and battlemind training as early interventions with soldiers returning from Iraq: randomization by platoon. J Consult Clin Psychol. 2009;77:928–40.PubMedCrossRefGoogle Scholar
- Alderman N, Knight C, Morgan C. Use of a modified version of the Overt Aggression Scale in the measurement and assessment of aggressive behaviours following brain injury. Brain Inj. 1997;11(7):503–23.PubMedGoogle Scholar
- Alderman N. Prevalence, characteristics and causes of aggressive behaviour observed within a neurobehavioural rehabilitation service: Predictors and implications for management. Brain Injury. 2007;21(9):891–911.PubMedGoogle Scholar
- Alexander MP. Mild traumatic brain injury: pathophysiology, natural history and clinical management. Neurology. 1995;45:1253–60.PubMedCrossRefGoogle Scholar
- Alla S, Sullivan S, Hale L, McCrory P. Self report scales/checklists for the measurement of concussion symptoms: a systematic review. Br J Sports Med. 2009;43: i3–12.PubMedCrossRefGoogle Scholar
- American Academy of Neurology. Practice parameter: the management of concussion in sports. Neurology. 1997;48:581–5.CrossRefGoogle Scholar
- American Congress of Rehabilitation Medicine. Definition of mild traumatic brain injury. J Head Trauma Rehabil. 1993;8:86–7.CrossRefGoogle Scholar
- American Psychiatric Association. Diagnostic and statistical manual of mental disorders, fourth edition, text revision. Washington, DC: American Psychiatric Association; 2000.CrossRefGoogle Scholar
- Arango-Lasprilla JC, Ketchum JM, Dezfulian T, Kreutzer JS, O’neil-Pirozzi TM, Hammond F, Jha A. Predictors of marital stability 2 years following traumatic brain injury. Brain Injury. 2008;22(7):565–74.PubMedGoogle Scholar
- Baguley IJ, Cooper J, Felmingham KL. Aggressive behavior following traumatic brain injury: How common is common? Journal of Head Trauma Rehabilitation. 2006;21:45–57.PubMedGoogle Scholar
- Barratt ES, Kent TA, Bryant SG, Felthous AR: A controlled trial of phenytoin in impulsive aggression. J Clin Psychopharmacol 1991;11:388–9.PubMedGoogle Scholar
- Barratt ES, Stanford MS, Kent TA, et al: Neuropsychological and cognitive psychophysiological substrates of impulsive aggression. Biol Psychiatry 1997; 41:1045–1047.PubMedGoogle Scholar
- Barratt ES, Stanford MS, Kent TA, et al. Neuropsychological and cognitive psychophysiological substrates of impulsive aggression. Biol Psychiatry. 1997a;41:1045–7.PubMedCrossRefGoogle Scholar
- Barratt ES, Stanford MS, Felthous AR, Kent TA. The effects of phenytoin on impulsive and premeditated aggression: a controlled study (1997a). J Clin Psychopharmacol. 1997b;17(5):341–9.PubMedCrossRefGoogle Scholar
- Bay E, Donders J. Risk factors for depressive symptoms after mild-to-moderate traumatic brain injury Brain Injury. 2008;22(3):233–41.PubMedGoogle Scholar
- Beck AT, Steer RA, Garbin MG. Psychometric properties of the Beck Depression Inventory: twenty-five years of evaluation. Clin Psychol Rev. 1988;8:77–100.PubMedGoogle Scholar
- Belanger HG, Curtiss G, Demery JA, Lebowitz BK, Vanderploeg RD. Factors moderating neuropsychological outcomes following mild traumatic brain injury: A meta-analysis. Journal of the International Neuropsychological Society. 2005;11:215–27.PubMedCrossRefGoogle Scholar
- Bell KR, Hoffman JM, Temkin NR, Powell JM, Fraser RT, Esselman PC, Barber JK, Dikmen S. The effect of telephone counseling on reducing post-injury traumatic symptoms after mild traumatic brain injury: a randomized trial. J Neurol Neurosurg Psychiatry. 2008;79:1275–81.PubMedCrossRefGoogle Scholar
- Binder LM, Rohling ML. Money matters: a meta-analytic review of the effects of financial incentives on recovery after closed head injury. Am J Psychiatry. 1996;153:7–10.PubMedGoogle Scholar
- Binder LM, Rohling ML, Larrabee GL. A review of mild head trauma. Part I: meta-analytic review of neuropsychological studies. J Clin Exp Neuropsychol. 1997;19:421–31.PubMedCrossRefGoogle Scholar
- Boake C, McCauley SR, Levin HS, Pedroza C, Contant CF, et al. Diagnostic criteria for post-concussional syndrome after mild to moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2005;17:350–6.PubMedCrossRefGoogle Scholar
- Borg J, Holm L, Peloso PM, Cassidy JD, von Holst H, Cassidy JD, et al. Non-surgical intervention and cost for mild traumatic brain injury: results of the WHO collaborating centre task force in mild traumatic brain injury. J Rehabil Med. 2004;43:76–83.PubMedCrossRefGoogle Scholar
- Brain Injury Association of America. TBI Incidence Factsheet. Retrieved 11 April 2009 from: http://www.biausa.org/elements/aboutbi/factsheets/TBIincidence.pdf.
- Brewer-Smyth, K., Burgess, AW, Shults, J. Physical and sexual abuse, salivary cortisol, and neurologic correlates of violent criminal behaviors in female prison inmates. Biological Psychiatry. 2004;55:21–31.PubMedGoogle Scholar
- Bryant RA. Posttraumatic stress disorder and traumatic brain injury: Can they co-exist? Clinical Psychology Review. 2001;21:931–48.PubMedGoogle Scholar
- Bryant RA, Harvey AG. Acute stress response: a comparison of head injured and non-head injured patients. Psychol Med. 1995;25:869–74.PubMedCrossRefGoogle Scholar
- Bryant RA, Harvey AG. Relationship between acute stress disorder and posttraumatic stress disorder following mild traumatic brain injury. Am J Psychiatry. 1998;155: 625–9.PubMedGoogle Scholar
- Bryant RA, Harvey AG. Postconcussive symptoms and posttraumatic stress disorder after mild traumatic brain injury. J Nerv Ment Dis. 1999;187:302–5.PubMedCrossRefGoogle Scholar
- Buss AH, Perry M. The Aggression Questionnaire. J Pers Soc Psychol. 1992;63:452–9.PubMedCrossRefGoogle Scholar
- Carroll LJ, Cassidy D, Peloso PM, Borg J, Holst H, Holm L, Paniak C, Pepin M. Prognosis for mild traumatic brain injury: results of the WHO collaborating centre task force and mild traumatic brain injury. J Rehabil Med. 1994;43:84–105.Google Scholar
- Cassidy JD, Carroll LJ, Peloso PM, Borg J, von Holst H, et al. Incidence, risk factors and prevention of mild traumatic brain injury: results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med. 2004;43:28–60.PubMedCrossRefGoogle Scholar
- Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. Report to Congress on mild traumatic brain injury in the United States: steps to prevent a serious public health problem. Atlanta, GA: Centers for Disease Control and Prevention; 2003.Google Scholar
- Chamelian L, Feinstein A. The effects of major depression on subjective and objective cognitive deficits in mild to moderate traumatic brain injury; 2006.PubMedGoogle Scholar
- Champion HR, Holcomb JB, Young LA. Injuries from explosions. Journal of Trauma. 2009;66(5):1468–76.PubMedGoogle Scholar
- Comper P, Bisschop S, Carnide N, Triccio A. A systematic review of treatments for mild traumatic brain injury. Brain Inj. 2005;19:863–80.PubMedCrossRefGoogle Scholar
- Damasio H, Grabowski T, Frank R, Galaburda AM, Damasio AR. The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science. 1994;264:1102–5.PubMedCrossRefGoogle Scholar
- Deb S, Crownshaw T. The role of pharmacotherapy in the management of behaviour disorders in traumatic brain injury patients. Brain Inj. 2004;18:1–31.PubMedCrossRefGoogle Scholar
- De Kruijk JR, Leffers P, Menheere P, Meerhoff S, Rutten J, Twijnstra A. Prediction of post-traumatic complaints after mild traumatic brain injury: early symptoms and biochemical markers. J Neurol Neurosurg Psychiatry. 2002;73:727–32.PubMedCrossRefGoogle Scholar
- DelBello MP, Soutullo CA, Zimmerman ME, Sax KW, Williams JR, McElroy SL, Strakowski SM. Traumatic brain injury in individuals convicted of sexual offenses with and without bipolar disorder. Psychiatry Research. 1999;89:281–86.PubMedGoogle Scholar
- Department of Veterans Affairs & Department of Defense. VA/DOD clinical practice guideline for management of concussion/mild traumatic brain injury (v1.0); 2009.Google Scholar
- Dikmen S, McLean A, Temkin N. Neuropsychological and psychosocial consequences of minor head injury. J Neurol Neurosurg Psychiatry. 1986;49:1227–32.PubMedCrossRefGoogle Scholar
- Dikmen S, Machamer J, Winn H, Temkin N. Neuropsychological outcome at 1-year post head injury. Neuropsychology. 1995a;9:80–90.CrossRefGoogle Scholar
- Dikmen S, Ross B, Machamer J, Tempkin N. One year psychosocial outcome in head injury. J Int Neuropsychol Soc. 1995b;1:67–77.PubMedCrossRefGoogle Scholar
- Draper K, Ponsford J, Schonberger M. Psychosocial and emotional outcomes 10 years following traumatic brain injury. Journal of Head Trauma Rehabilitation. 2007;22:278–87.PubMedGoogle Scholar
- Dyer KFW, Bell R, McCann J, Rauch R. Aggression after traumatic brain injury: Analysing socially desirable responses and the nature of aggressive traits’, Brain Injury. 2006;20(11):1163–73.PubMedGoogle Scholar
- Fann JR, Katon WJ, Uomoto JM, Esselman PC. Psychiatric disorders and functional disability in outpatients with traumatic brain injuries. Am J Psychiatry. 1995;152(10):1493–99.PubMedGoogle Scholar
- Faul M, Xu L, Wald MM, Coronado VG. Traumatic brain injury in the United States: emergency department visits, hospitalizations, and deaths. Atlanta (GA): Centers for Disease Control and Prevention, National Center for Injury Prevention and Control; 2010.PubMedGoogle Scholar
- Gil S, Caspi Y, Ben-Ari IZ, Koren D, Klein E. Does memory of a traumatic event increase the risk for posttraumatic stress disorder in patients with traumatic brain injury? A prospective study. Am J Psychiatry. 2005;162: 963–9.PubMedCrossRefGoogle Scholar
- Glenn MB, O’Neil-Pirozzi T, Goldstein R, Burke D, Jacob L. Depression amongst outpatients with traumatic brain injury. Brain Inj. 2001;15(9):811–18.PubMedGoogle Scholar
- Gondusky JS, Reiter MP. Protecting military convoys in Iraq: an examination of battle injuries sustained by a mechanized battalion during Operation Iraqi Freedom II. Mil Med. 2005;170:546–9.PubMedGoogle Scholar
- Grafman J, Schwab K, Warden D, Pridgen A, Brown HR, Salazar AM. Frontal lobe injuries, violence, and aggression: a report of the Vietnam Head Injury Study. Neurology. 1996;46:1231–38.PubMedGoogle Scholar
- Greve KW, Sherwin E, Stanford MS, et al. Personality and neurocognitive correlates of impulsive aggression in long-term survivors of severe traumatic brain injury. Brain Inj. 2001;15:255–62.PubMedCrossRefGoogle Scholar
- Greve KW, Love J, Sherwin E, et al. Cognitive strategy usage in long term survivors of severe traumatic brain injury with persisting impulsive aggression. Pers Indiv Differ. 2002;32:639–47.CrossRefGoogle Scholar
- Hoge CW, Goldberg HM, Castro CA. Care of war veterans with mild traumatic brain injury-flawed perspective. N Engl J Med. 2009;360:1588–91.PubMedCrossRefGoogle Scholar
- Hoge CW, McGurk D, Thomas JL, Cox AL, Engel CC, et al. Mild traumatic brain injury in U.S. soldiers returning from Iraq. N Engl J Med. 2008;358:453–63.PubMedCrossRefGoogle Scholar
- Haller J, Kruk MR. Normal and abnormal aggression: human disorders and novel laboratory models. Neurosci Biobehav Rev. 2006;30(3):292–303.PubMedCrossRefGoogle Scholar
- Hibbard MR, Uysal S, Kepler K, Bogdany J, Silver J. Axis I psychopathology in individuals with traumatic brain injury. J Head Trauma Rehabil. 1998;13(4):24–39.PubMedGoogle Scholar
- Hibbard MR, Ashman TA, Spielman LA, Chun D, Charatz HJ, Melvin S. Relationship between depression and psychosocial functioning after traumatic brain injury. Arch Phys Med Rehabil. 2004;85(4 suppl 2)43–53.PubMedGoogle Scholar
- Hoaken PNS, Steward SH. Drugs of abuse and the elicitation of human aggressive behavior. Addict Behav. 2003;28:1533–54.PubMedCrossRefGoogle Scholar
- Horner, MD, Selassie, AW, Lineberry, L, Ferguson, PL, Labbate, LA. Predictors of psychological symptoms 1 year after traumatic brain injury: A population-based epidemiological study. Journal of Head Trauma Rehabilitation. 2008;23:74–83.PubMedCrossRefGoogle Scholar
- Iverson GL, McCracken LM. “Postconcussive” symptoms in persons with chronic pain. Brain Inj. 1997;11:783–90.PubMedCrossRefGoogle Scholar
- Jaffee MS, Helmick KM, Girard PD, Meyer KS, Dinegar K, et al. Acute clinical care and care coordination for traumatic brain injury within Department of Defense. J Rehabil Res Dev. 2009;46:655–66.PubMedCrossRefGoogle Scholar
- Johnson R, Balleny H. Behaviour problems after brain injury: incidence and need for treatment. Clin Rehabil. 1996;10:173–81.CrossRefGoogle Scholar
- Jorge R, Robinson RG. Mood disorders following traumatic brain injury. Neurorehabilitation. 2002;17(4):311–24.PubMedGoogle Scholar
- Kashluba S, Hanks RA, Casey JE, Millis SR. Neuropsychologic and functional outcome after complicated mild traumatic brain injury. Arch Phys Med Rehabil. 2008;89:904–11.PubMedCrossRefGoogle Scholar
- Keiski MA, Shore DL, Hamilton, JM. The Role of Depression in Verbal Memory Following Traumatic Brain Injury. The Clinical Neuropsychologist. 2006;21(5):744–61.PubMedGoogle Scholar
- Kelly G, Brown S, Todd J, Kremer P. Challenging behaviour profiles of people with acquired brain injury living in community settings. Brain Injury. 2008;22(6):457–70.PubMedGoogle Scholar
- Kennedy JE, Jaffee MS, Leskin GA, Stokes JW, Leal FO, et al. Posttraumatic stress disorder and posttraumatic stress disorder-like symptoms and mild traumatic brain injury. J Rehabil Res Dev. 2007;44:895–920.PubMedCrossRefGoogle Scholar
- Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV-TR disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry. 2005; 62(6):617–27.PubMedCrossRefGoogle Scholar
- Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry. 1995;52: 1048–60.PubMedCrossRefGoogle Scholar
- Kim E. Agitation, aggression, and disinhibition syndromes after traumatic brain injury. Neurorehabilitation. 2002;17: 297–310.PubMedGoogle Scholar
- King NS. PTSD and traumatic brain injury: folklore and fact? Brain Inj. 2008;22:1–5.PubMedCrossRefGoogle Scholar
- Knuth T, Letarte PB, Ling G, Moores LE, Rhee P, et al. Guidelines for the field management of combat related head trauma. New York, NY: Brain Trauma Foundation; 2005. p. 2005.Google Scholar
- Koren D, Norman D, Cohen A, Berman J, Klein EM. Increased PTSD risk with combat-related injury: a matched comparison study of injured and uninjured soldiers experiencing the same combat events. Am J Psychiatry. 2005;162:276–82.PubMedCrossRefGoogle Scholar
- Kraus JF, Nourjah P. The epidemiology of mild, uncomplicated brain injury. J Trauma. 1988;28:1637–43.PubMedCrossRefGoogle Scholar
- Kwok FA, Lee TM, Leung CH, Poon WS. Changes of cognitive functioning following mild traumatic brain injury over a 3-month period. Brain Injury. 2008;22: 740–51.PubMedCrossRefGoogle Scholar
- Landre N, Poppe CJ, Davis N, Schmaus B, Hobbs SE. Cognitive functioning and postconcussive symptoms in trauma patients with and without mild TBI. Archives of Clinical Neuropsychology. 2006;21:255–73.PubMedCrossRefGoogle Scholar
- Lees-Haley PR, Fox DD, Courtney JC. A comparison of complaints by mild brain injury claimants and other claimants describing subjective experiences immediately following their injury. Arch Clin Neuropsychol. 2001;16:689–95.PubMedGoogle Scholar
- Levin HS, Amparo E, Eisenberg HM, Williams DH, High Jr WM, et al. Magnetic resonance imaging and computerized tomography in relation to the neurobehavioral sequelae of mild and moderate head injuries. J Neurosurg. 1987;66:706–13.PubMedCrossRefGoogle Scholar
- Levin HS, et al. Depression and posttraumatic stress disorder at three months after mild to moderate traumatic brain injury. J Clin Exp Neuropsychol. 2001;23: 754–69.PubMedCrossRefGoogle Scholar
- Levin HS, McCauley SR, Pedroza Josic C, Boake C, Brown SA, Goodman HS, Merrit SG, Brundage SI. Predicting depression following mild traumatic brain injury. Arch Gen Psychiatry. 2005;62:523–8.PubMedCrossRefGoogle Scholar
- Lezak M, Howieson D, Loring D. Neuropsychological assessment. 4th ed. New York, NY: Oxford University Press; 2004.Google Scholar
- Machamer JE, Temkin NR, Dikmen SS. Neurobehavioral outcome in persons with violent or normal traumatic brain injury. Journal of Head Trauma Rehabilitation. 2003;18;387–97.PubMedGoogle Scholar
- Maiuro RD, Vitaliano PP, Chan TS. A brief measure of for the assessment of anger and aggression. J Interpers Violence. 1987;2:166–78.CrossRefGoogle Scholar
- Marsh NV, Martinovich WM. Executive dysfunction and domestic violence. Brain Inj. 2006;20(1):61–6.PubMedGoogle Scholar
- Mayou RA, Black J, Bryant B. Unconsciousness, amnesia, and psychiatric symptoms following road traffic accident injury. Br J Psychiatry. 2000;177:540–5.PubMedCrossRefGoogle Scholar
- McCloskey MS, Noblett KL, Deffenbacher JL, Gollan JK, Coccaro EF. Cognitive-behavioral therapy for intermittent explosive disorder: A pilot randomized clinical trial. Journal of Consulting and Clinical Psychology. 2008;76:876–86.PubMedGoogle Scholar
- McCrea M, Guskiewicz KM, Marshall SW. Acute effects and recovery time following concussion in collegiate football players: the NCAA concussion study. JAMA. 2003;290:2556–63.PubMedCrossRefGoogle Scholar
- McCrea M, Kelly JP, Randolph C, Kluge J, Bartolic E, et al. Standardized assessment of concussion (SAC): on-site mental status evaluation of the athlete. J Head Trauma Rehabil. 1998;13:27–35.PubMedCrossRefGoogle Scholar
- McCrea M. Mild traumatic brain injury and postconcussion syndrome: the new evidence base for diagnosis and treatment. New York, NY: Oxford University Press; 2008.Google Scholar
- McCrea M, Randolph C, Kelly JP. Standardized Assessment for Concussion (SAC): manual for administration, scoring, and interpretation. 2nd ed. Waukesha, WI: CNS Inc.; 2000.Google Scholar
- Mental Health Advisory Team V (2008). Full Report. Retrieved from: http://www.armymedicine.army.mil/reports/mhat/mhat_v/mhat-v.cfm.PubMedGoogle Scholar
- Middelboe T, Anderson HS, Birket-Smith M, Friis ML. Minor head injury: impact on general health after 1 year. A prospective follow-up study. Acta Neurol Scand. 1991;85:5–9.CrossRefGoogle Scholar
- Miller L, Mittenberg W. Brief cognitive behavioral interventions in mild traumatic brain injury. Appl Neuropsychol. 1998;5:172–83.PubMedCrossRefGoogle Scholar
- Miller LA, Collins RL, Kent TA. Language and the modulation of impulsive aggression. The Journal of Neuropsychiatry and Clinical Neurosciences. 2008; 20:261–73.PubMedCrossRefGoogle Scholar
- Mittenberg W, DiGiulio DV, Perrin S, Bass AE. Symptoms following mild head injury: expectation as aetiology. J Neurol Neurosurg Psychiatry. 1992;55:200–4.PubMedCrossRefGoogle Scholar
- Mittenberg W, Tremont G, Zielinski RE, Fichera S, Rayls KR. Cognitive-behavioral prevention of postconcussion syndrome. Arch Clin Neuropsychol. 1996;11: 139–45.PubMedGoogle Scholar
- Moeller FG, Barratt ES, Dougherty DM, Schmitz JM, Swann AC. Psychiatric aspect of impulsivity. Am J Psychiatry. 2001;158:1783–93.PubMedCrossRefGoogle Scholar
- Moldover JE, Goldberg KB, ProutMF. Depression after traumatic brain injury: a review of evidence for clinical heterogeneity. Neuropsychol Rev. 2004;14(3):143–54.PubMedGoogle Scholar
- Mooney G, Speed J, Sheppard S. Factors related to recovery after mild traumatic brain injury. Brain Injury. 2005;19:12975–87.PubMedGoogle Scholar
- Moore EL, Terryberry-Spohr L, Hope DA. Mild traumatic brain injury and anxiety sequelae: a review of the literature. Brain Inj. 2006;20:117–32.PubMedCrossRefGoogle Scholar
- National Institute of Neurological Disorders and Stroke. Traumatic Brain Injury: Hope through Research. Bethesda, MD: National Institute of Health; 2002.PubMedGoogle Scholar
- Niemeier JP, Marwitz JH, Lesher K, Walker WC, Bushnik T. Gender differences in executive functions following traumatic brain injury. 2007;17:293–313.PubMedGoogle Scholar
- Nott MT, Chapparo C, Baguley IJ. Agitation following traumatic brain injury: An Australian sample. Brain Injury. 2006;20(11):1175–82.PubMedGoogle Scholar
- Ohry A, Rattok J, Solomon Z. Post-traumatic stress disorder in brain injury patients. Brain Inj. 1996;10:687–95.PubMedCrossRefGoogle Scholar
- Orth U, Wieland E. Anger, hostility, and posttraumatic stress disorder in trauma-exposed adults: a meta-analysis. J Consult Clin Psychol. 2006;74:698–706.PubMedGoogle Scholar
- Oquendo MA, Friedman JH, Grunebaum MF, Burke A, Silver JM, Mann JJ. Suicidal behavior and mild traumatic brain injury in major depression. Journal of Nervous and Mental Disease. 2004;192:430–34.PubMedGoogle Scholar
- Paniak C, Reynolds S, Phillips K, Toller-Lobe G, Melnyk A, Nagy J. Patient complaints within 1 month of mild traumatic brain injury: a controlled study. Arch Clin Neuropsychol. 2002a;17:319–34.PubMedGoogle Scholar
- Paniak C, Reynolds S, Toller-Lobe G, Melnyk A, Nagy J. A longitudinal study of the relationship between financial compensation and symptoms after treated mild traumatic brain injury. J Clin Exp Neuropsychol. 2002b;24:187–93.PubMedCrossRefGoogle Scholar
- Paniak C, Toller-Lobe G, Durand J, Nagy J. A randomized trial of two treatments for mild traumatic brain injury. Brain Inj. 1998;12:1011–23.PubMedCrossRefGoogle Scholar
- Paniak C, Toller-Lobe G, Reynolds S, Melnyk A, Nagy J. A randomized trial of two treatments for mild traumatic brain injury: 1 year follow up. Brain Inj. 2000;14:219–26.PubMedCrossRefGoogle Scholar
- Pietrzak RH, Johnson DC, Goldstein MB, Malley JC, Southwick SM. Posttraumatic stress disorder mediates the relationship between mild traumatic brain injury and health and psychosocial functioning in veterans of Operations Enduring Freedom and Iraqi Freedom. J NervMent Dis. 2009;197:748–53.CrossRefGoogle Scholar
- Piland SG, Motl RW, Guskiewicz KM, McCrea M, Ferrara MS. Structural validity of a self-report concussion-related symptom scale. Med Sci Sports Exer. 2006;38:27–32.CrossRefGoogle Scholar
- Potter S, Leigh E, Wade D, Fleminger S. The Rivermead Post Concussion Symptoms Questionnaire: a confirmatory factor analysis. J Neurol. 2006;253:1603–14.PubMedCrossRefGoogle Scholar
- Rapoport MJ, McCullagh S, Streiner D, Feinstein A. Age and major depression after mild traumatic brain injury. Am J Geriatr Psychiatry. 2003;11:365–9.PubMedGoogle Scholar
- Raskin MA. Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study. Am J Psychiary. 2003;160:371–3.CrossRefGoogle Scholar
- Rimel RW, Giordani B, Barth JT, Boll TJ, Jane JA. Disability caused by minor head injury. Neurosurgery. 1981;9:221–8.PubMedCrossRefGoogle Scholar
- Rosenthal M, Christensen BK, Ross TP. Depression following traumatic brain injury. Arch Phys Med Rehabil. 1998;79(1):90–103.PubMedCrossRefGoogle Scholar
- Ruff R. Two decades of advances in understanding of mild traumatic brain injury. J Head Trauma Rehabil. 2005;20:5–18.PubMedCrossRefGoogle Scholar
- Ryan LM, Warden DL. Post concussion syndrome. Int Rev Psychiatry. 2003;15:310–6.PubMedCrossRefGoogle Scholar
- Sbordone RJ, Liter JC. Mild traumatic brain injury does not produce post-traumatic stress disorder. Brain Inj. 1995;9:405–12.PubMedCrossRefGoogle Scholar
- Schretlen DJ, Shapiro AM. A quantitative review of the effects of traumatic brain injury on cognitive functioning. Int Rev Psychiatry. 2003;15:341–9.PubMedCrossRefGoogle Scholar
- Schopp LH, Shigaki CL, Bounds TA, Johnstone B, Stucky RC, Conway, BA. Outcomes in TBI with violent versus nonviolent etiology in a predominantly rural setting. Journal of Head Trauma Rehabilitation. 2006;21:213–25.PubMedGoogle Scholar
- Schwab KA, Warden D, Lux WE, Shupenko LA, Zitnay G. Defense and Veteran Brain Injury Center: Peacetime and wartime missions. Journal of Rehabilitation Research and Development. 2007; xiii–xxi.PubMedCrossRefGoogle Scholar
- Seel RT, Kreutzer JS, Rosenthal M, Hammond FM, Corrigan JD, Black K. Depression after traumatic brain injury: a National Institute on Disability and Rehabilitation Research Model Systems multicenter investigation. Arch PhysMed Rehabil. 2003;84(2):177–84.PubMedGoogle Scholar
- Silver JM, Yudofsky SC. Organic mental disorders and impulsive aggression in impulsivity and aggression. In: Hollander E, Stein DJ, editors. John Wiley & Sons, Ltd; 1995.Google Scholar
- Simpson G, Tate R. Suicidality in people surviving a traumatic brain injury: prevalence, risk factors and implications for clinical management. Brain Inj. 2007;21:1335–51.PubMedCrossRefGoogle Scholar
- Slaughter B, Fann JR, Ehde D. Traumatic brain injury in a county jail population: prevalence, neuropsychological functioning and psychiatric disorders. Brain Injury. 2003;17(9):731–41.PubMedGoogle Scholar
- Smith-Seemiller L, Fow NR, Kant R, Franzen MD. Presence of post-concussion syndrome symptoms in patients with chronic pain vs mild traumatic brain injury. Brain Inj. 2003;17:199–206.PubMedCrossRefGoogle Scholar
- Snell DL, Surgenor LJ, Hay-Smith JC, Siegert RJ. A systematic review of psychological treatments for mild traumatic brain injury: an update on the evidence. J Clin Exp Neuropsychol. 2009;31:20–38.PubMedCrossRefGoogle Scholar
- Sosin DM, Sniezek JE, Thurman DJ. Incidence of mild and moderate brain injury in the United States, 1991. Brain Inj. 1996;10:47–54.PubMedCrossRefGoogle Scholar
- Stanford MS, Houston RJ, Mathias CW, Villemarette-Pittman NR, Helfritz LE, Conklin SM. Characterizing aggressive behavior. Assessment. 2003;10:183–90.PubMedGoogle Scholar
- Stanford MS, Helfritz LE, Conklin SM, Villemarette-Pittman NR, Greve KW, Adams D, Houston RJ. A comparison of anticonvulsants in the treatment of impulsive aggression. Experimental and Clinical Psychopharmacology. 2005;13:72–77.PubMedGoogle Scholar
- Stein DJ, Moeller FG. The man who turned bad. CNS Spectrums. 2005;10:88–90.PubMedGoogle Scholar
- Tanielian T, Jaycox LH, editors. Invisible wounds of war: psychological and cognitive injuries, their consequences, and services to assist recovery. Santa Monica, CA: RAND; 2008.Google Scholar
- Tateno A, Jage RE, Robinson RG. Clinical correlates of aggressive behaviour after traumatic brain injury. The Journal of Neuropsychiatry and Clinical Neurosciences 2003;15:155–60.PubMedGoogle Scholar
- Teasdale TW, Engberg AW. Suicide after traumatic brain injury: a population study. J Neurol Neurosurg Psychiatry. 2001;71:436–40.PubMedCrossRefGoogle Scholar
- Terrio H, Brenner LA, Ivins BJ, Cho JM, Helmick K, Schwab K, Scally K, Bretthauer R, Warden D. Traumatic brain injury screening: Preliminary findings in a US Army brigade combat team. J Head Trauma Rehabil. 2009;24:14–23.PubMedCrossRefGoogle Scholar
- Teten AL, Miller LA, Stanford MS, Peterson N, Collins R, Bailey SD, Dunn NJ, Kent TA. Characterizing aggression and its association to anger and hostility among male veterans with posttraumatic stress disorder. Mil Med. 2010;175(6):405–10.PubMedGoogle Scholar
- Teten AL, Miller LA, Bailey SD, Dunn NJ, Kent TA. Empathic deficits and alexithymia in trauma-related impulsive aggression. Behav Sci Law. 2008;26: 823–32.PubMedCrossRefGoogle Scholar
- Villemarette-Pittman NR, Stanford MS, Greve KW. Language and executive function in self-reported impulsive aggression. Pers Individ Dif. 2003;34:1533–44.PubMedGoogle Scholar
- Wang Y, Chan RCK, Deng Y. Examination of postconcussion-like symptoms in healthy university students: Relationships to subjective and objective neuropsychological function performance. Arch Clin Neuropsychol. 2006;21:339–47.PubMedCrossRefGoogle Scholar
- Warden DL, Gordon B, McAllister TW, Silver JM, Barth JT, Bruns J, Drake A, Gentry T, Jagoda A, Katz DI, Kraus J, Labbate LA, Ryan LM, Sparling MB, Walters B, Whyte J, Zapata A, Zitnay G. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma. 2006;23(10):1468–501.PubMedCrossRefGoogle Scholar
- Wasserman L, Shaw T, Vu M, Ko C, Bollegala D, et al. An overview of traumatic brain injury and suicide. Brain Inj. 2008;22:811–9.PubMedCrossRefGoogle Scholar
- Williams DH, Levin HS, Eisenberg HM. Mild head injury classification. Neurosurgery. 1990;27:422–8.PubMedCrossRefGoogle Scholar
- Wood RL, Liossi C. Neuropsychological and neurobehavioral correlates of aggression following traumatic brain injury. Journal of Neuropsychiatry and Clinical Neurosciences. 2006;18:333–41.PubMedGoogle Scholar
- World Health Organization. The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. Geneva: World Health Organization; 1993.PubMedGoogle Scholar
- Yang CC, Hua MS, Tu YK, Huang SJ. Early clinical characteristics of patients with persistent post-concussion symptoms: A prospective study. Brain Inj. 2009;23: 299–306.PubMedCrossRefGoogle Scholar
- Yudofsky SC, et al. The Overt Aggression Scale for the objective rating of verbal and physical aggression. Am J Psychiatry. 1986;143(1):35–9.PubMedGoogle Scholar