Illicit drug abuse and renal disease

  • Cheryl L. Kunis
  • Nidhi Aggarwal
  • Gerald B. Appel
Chapter

The illicit use of drugs involves millions of people worldwide and is associated with a variety of medical complications. In recent years the abuse of both heroin and cocaine have produced major medical problems across the globe. Other illicit agents such as barbiturates, ethyl alcohol, amphetamines, and phencyclidine, as well as drug combina tions produce medical complications as well, sometimes with renal manifestations (Table 1). An estimate of 5-6% of new patients beginning treatment for end stage renal disease in the United States appear to have opiate-related kidney disease [1].

This chapter will review the various renal manifestations of illicit drug abuse. It will focus on the clinical and pathologic presentation, the course, the treatment, and the pathogenesis of these lesions. Secondary renal infectious complica tions will not be discussed, except for the interrelationship of HIV and heroin nephropathy.

Keywords

Acute Renal Failure Acute Kidney Injury Acute Tubular Necrosis Cocaine Abuse Acute Interstitial Nephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Cheryl L. Kunis
    • 1
  • Nidhi Aggarwal
    • 1
  • Gerald B. Appel
    • 1
  1. 1.Department of Medicine, Division of NephrologyColumbia University College of Physicians and SurgeonsNew YorkUSA

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