Quality of Life Issues During Adjuvant Endocrine Therapy

  • Lesley Fallowfield
  • Valerie Jenkins
Part of the Cancer Treatment and Research book series (CTAR, volume 151)

When the media report the results from studies reporting the latest breakthrough in adjuvant drug treatments, they are usually described in terms of relative rather than absolute benefits. Many women with early stage breast (EBC) cancer may not realise that they do not necessarily require any further adjuvant treatments and that claims for example of a 50% reduction in risk of recurrence does not relate to an individual woman’s risk. For many who receive systemic therapy the relative benefits may be small and not outweigh the associated costs of side effects. Until basic science can provide us with a better understanding of how to target treatments to those most likely to derive benefit, we need to collect side-effect data systematically and conduct considerably more research into ameliorative interventions to help patients cope with the worst symptoms.


Ameliorative Intervention Trial Outcome Index ATAC Trial Post Baseline Visit Goserelin Therapy 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Cancer Research UK Psychosocial Oncology Group, Brighton and Sussex Medical SchoolUniversity of SussexEast SussexUK
  2. 2.Brighton and Sussex Medical SchoolUniversity of SussexBrightonUK

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