Evolution of the Endoplasmic Reticulum and the Golgi Complex

  • Alexander A. Mironov
  • Victor V. Banin
  • Irina S. Sesorova
  • Viacheslav V. Dolgikh
  • Alberto Luini
  • Galina V. Beznoussenko

Abstract

By analyzing the morpho-physiological features of the Golgi complex, its relationship with the endoplasmic reticulum in different species, and the molecular machineries involved in intracellular transport, we conclude that; (1) all eukaryotic cells have either Golgi complexes or remnants thereof; (2) all eukaryotic cells have a large minimal set of proteins that are involved in intracellular transport; and (3) several indispensable molecular machines are always present in secreting eukaryotic cells. Using this information, our data about mechanisms of intra-Golgi transport and phylogenetic analysis of several molecular machines, we propose a model for the evolution of the Golgi complex and the endoplasmic reticulum.

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Copyright information

© Landes Bioscience and Springer Science+Business Media 2007

Authors and Affiliations

  • Alexander A. Mironov
    • 1
  • Victor V. Banin
    • 2
  • Irina S. Sesorova
    • 3
  • Viacheslav V. Dolgikh
    • 4
  • Alberto Luini
    • 1
  • Galina V. Beznoussenko
    • 1
  1. 1.Department of Cell Biology and OncologyMario Negri Sud InstituteSanta Maria Imbaro (Chieti)Italy
  2. 2.Research CenterRussian State Medical UniversityMoscowRussia
  3. 3.Department of BiologyShuja State Pedagogical UniversityShujaRussia
  4. 4.Laboratory of Microbiological Control All-Russian Institute for Plant ProtectionRussian Academy of Agricultural SciencesSt. Petersburg-PushkinRussia

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