The Enteroviruses: An Emerging Infectious Disease? The Real, the Speculative and the Really Speculative
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- Abzug M.J. (2008) The Enteroviruses: An Emerging Infectious Disease? The Real, the Speculative and the Really Speculative. In: Finn A., Pollard A.J. (eds) Hot Topics in Infection and Immunity in Children IV. Advances in Experimental Medicine and Biology, vol 609. Springer, New York, NY
The human enteroviruses (EVs), which include the polioviruses, Coxsackie A and B viruses, ECHO viruses, and numbered EVs, produce a well-recognized list of clinical manifestations, ranging from mild febrile illness, respiratory infections, and characteristic exanthematous and enanthematous diseases such as hand-foot-mouth disease and herpangina, to potentially severe illnesses such as myocarditis, encephalitis, and neonatal sepsis (Table 1). The EVs have also been linked to a variety of other conditions, including chronic autoimmune diseases, cardiovascular diseases, and neurologic diseases, although definitive proof of causation is lacking (Table 2) (Palacios and Oberste 2005).
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