The Genus Yersinia pp 211-216

Part of the Advances In Experimental Medicine And Biology book series (AEMB, volume 603)

Environmental Stimuli Affecting Expression of the Ysa Type Three Secretion Locus

  • Shirly Mildiner-Earley
  • Virginia L. Miller
  • Kimberly A. Walker

Yersinia enterocolitica has two type III secretion systems (TTSS): The well characterized Ysc-Yop system and the relatively uncharacterized Ysa-Ysp system. Detection of Ysps in culture supernatants has only been observed in vitro when cultures are grown at low temperature (26°C) and in high salt (290mM NaCl). Previous reports demonstrated that expression from the ysaE promoter was activated by high salt. In this study, we report a new environmental stimulus for ysa gene expression; in the presence of high salt, growth on solid surface stimulates expression 7-fold compared to growth in high salt broth. These new data indicate that, in the presence of salt, solid surface is an extremely robust signal for the Ysa system.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Shirly Mildiner-Earley
    • 1
  • Virginia L. Miller
    • 2
  • Kimberly A. Walker
    • 1
  1. 1.Molecular MicrobiologyWashington UniversitySt. LouisUSA
  2. 2.Molecular Microbiology and PediatricsWashington UniversitySt. LouisUSA

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