Neural Crest and the Development of the Enteric Nervous System

  • Richard B. Anderson
  • Donald F. Newgreen
  • Heather M. YoungEmail author
Part of the Advances in Experimental Medicine and Biology book series (volume 589)


The formation of the enteric nervous system (ENS) is a particularly interesting example of the migratory ability of the neural crest and of the complexity of structures to which neural crest cells contribute. The distance that neural crest cells migrate to colonize the entire length of the gastrointestinal tract exceeds that of any other neural crest cell population. Furthermore, this migration takes a long time—over 25% of the gestation period for mice and around 3 weeks in humans. After colonizing the gut, neural crest-derived cells within the gut wall then differentiate into glial cells plus many different types of neurons, and generate the most complex part of the peripheral nervous system.


Neural Crest Neural Crest Cell Crest Cell Enteric Nervous System Neural Crest Stem Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2006

Authors and Affiliations

  • Richard B. Anderson
    • 1
  • Donald F. Newgreen
    • 2
  • Heather M. Young
    • 1
    Email author
  1. 1.Department of Anatomy & Cell BiologyUniversity of MelbourneMelbourneAustralia
  2. 2.Murdoch Childrens Research InstituteParkvilleAustralia

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