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HIV–HBV and HIV–HCV Coinfection and Liver Cancer Development

  • Jianming Hu
  • Laurie Ludgate
Part of the Cancer Treatment and Research book series (CTAR, volume 133)

Keywords

Woodchuck Hepatitis Virus Liver Cancer Development 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Thomas, D. L. 2006. Growing importance of liver disease in HIV-infected persons. Hepatology 43(2 Suppl 1):S221–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Cacoub, P., L. Geffray, E. Rosenthal, et al. 2001. Mortality among human immunodeficiency virus-infected patients with cirrhosis or hepatocellular carcinoma due to hepatitis C virus in French Departments of Internal Medicine/Infectious Diseases, in 1995 and 1997. Clin Infect Dis 32(8):1207–14.PubMedCrossRefGoogle Scholar
  3. 3.
    Ganem, D., and A. M. Prince. 2004. Hepatitis B virus infection – natural history and clinical consequences. N Engl J Med 350(11):1118–29.PubMedCrossRefGoogle Scholar
  4. 4.
    Yim, H. J., and A. S. Lok. 2006. Natural history of chronic hepatitis B virus infection: What we knew in 1981 and what we know in 2005. Hepatology 43(2 Suppl 1):S173–81.PubMedCrossRefGoogle Scholar
  5. 5.
    Wright, T. L. 2006. Introduction to chronic hepatitis B infection. Am J Gastroenterol 101(Suppl 1):S1–6.PubMedCrossRefGoogle Scholar
  6. 6.
    Lindenbach, B. D., and C. M. Rice, Unravelling hepatitis C virus replication from genome to function. Nature, 2005. 436(7053): p. 933–8.PubMedCrossRefGoogle Scholar
  7. 7.
    Chen, S. L., and T. R. Morgan. 2006. The natural history of hepatitis C virus (HCV) infection. Int J Med Sci 3(2):47–52.PubMedGoogle Scholar
  8. 8.
    Seeff, L. B. 1999. Natural history of hepatitis C. Am J Med 107(6B):10S–15S.PubMedCrossRefGoogle Scholar
  9. 9.
    Park, J. S., N. Saraf, and D. T. Dieterich. 2006. HBV plus HCV, HCV plus HIV, HBV plus HIV. Curr Gastroenterol Rep 8(1):67–74.PubMedCrossRefGoogle Scholar
  10. 10.
    Alter, M. J. 2006. Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 44(1 Suppl):S6–9.PubMedCrossRefGoogle Scholar
  11. 11.
    Lascar, R. M., A. R. Lopes, R. J. Gilson, et al. 2005. Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection. J Infect Dis 191(7):1169–79.PubMedCrossRefGoogle Scholar
  12. 12.
    Yeo, W., K. C. Lam, B. Zee, et al. 2004. Hepatitis B reactivation in patients with hepatocellular carcinoma undergoing systemic chemotherapy. Ann Oncol 15(11):1661–6.PubMedCrossRefGoogle Scholar
  13. 13.
    Sterling, R. K., and M. S. Sulkowski. 2004. Hepatitis C virus in the setting of HIV or hepatitis B virus coinfection. Semin Liver Dis 24(Suppl 2):61–8.PubMedCrossRefGoogle Scholar
  14. 14.
    Liu, Z., and J. Hou. 2006. Hepatitis B virus (HBV) and hepatitis C virus (HCV) dual infection. Int J Med Sci 3(2):57–62.PubMedGoogle Scholar
  15. 15.
    Chemin, I., and C. Trepo. 2005. Clinical impact of occult HBV infections. J Clin Virol 34(Suppl 1):S15–21.PubMedCrossRefGoogle Scholar
  16. 16.
    Tamori, A., S. Nishiguchi, S. Shiomi, et al. 2005. Hepatitis B virus DNA integration in hepatocellular carcinoma after interferon-induced disappearance of hepatitis C virus. Am J Gastroenterol 100(8):1748–53.PubMedCrossRefGoogle Scholar
  17. 17.
    Michalak, T. I., P. M. Mulrooney, and C. S. Coffin. 2004. Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver. J Virol 78(4):1730–8.PubMedCrossRefGoogle Scholar
  18. 18.
    Pal, S., D. G. Sullivan, S. Kim, et al. 2006. Productive replication of hepatitis C virus in perihepatic lymph nodes in vivo: Implications of HCV lymphotropism. Gastroenterology 130(4):1107–16.PubMedCrossRefGoogle Scholar
  19. 19.
    Brechot, C. 2004. Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms. Gastroenterology 127(5 Suppl 1):S56–61.PubMedCrossRefGoogle Scholar
  20. 20.
    Branda, M., and J. R. Wands. 2006. Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma. Hepatology 43(5):891–902.PubMedCrossRefGoogle Scholar
  21. 21.
    Thorgeirsson, S. S., and J. W. Grisham. 2002. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31(4):339–46.PubMedCrossRefGoogle Scholar
  22. 22.
    Fattovich, G., T. Stroffolini, I. Zagni, et al. 2004. Hepatocellular carcinoma in cirrhosis: Incidence and risk factors. Gastroenterology 127(5 Suppl 1):S35–50.PubMedCrossRefGoogle Scholar
  23. 23.
    Chen, J. G., J. Zhu, D. M. Parkin, et al. 2006. Trends in the incidence of cancer in Qidong, China, 1978–2002. Int J Cancer.Google Scholar
  24. 24.
    Davila, J. A., R. O. Morgan, Y. Shaib, et al. 2004. Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: A population-based study. Gastroenterology 127(5):1372–80.PubMedCrossRefGoogle Scholar
  25. 25.
    El-Serag, H. B. 2004. Hepatocellular carcinoma: Recent trends in the United States. Gastroenterology 127(5 Suppl 1):S27–34.PubMedCrossRefGoogle Scholar
  26. 26.
    Parkin, D. M. 2006. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 118(12):3030–44.PubMedCrossRefGoogle Scholar
  27. 27.
    Tradati, F., M. Colombo, P. M. Mannucci, et al. 1998. A prospective multicenter study of hepatocellular carcinoma in Italian hemophiliacs with chronic hepatitis C. The Study Group of the Association of Italian Hemophilia Centers. Blood 91(4):1173–7.PubMedGoogle Scholar
  28. 28.
    Liang, T. J., and T. Heller. 2004. Pathogenesis of hepatitis C-associated hepatocellular carcinoma. Gastroenterology 127(5 Suppl 1):S62–71.PubMedCrossRefGoogle Scholar
  29. 29.
    Block, T. M., A. S. Mehta, C. J. Fimmel, et al. 2003. Molecular viral oncology of hepatocellular carcinoma. Oncogene 22(33):5093–107.PubMedCrossRefGoogle Scholar
  30. 30.
    Anzola, M. 2004. Hepatocellular carcinoma: Role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis. J Viral Hepat 11(5):383–93.PubMedCrossRefGoogle Scholar
  31. 31.
    Cougot, D., C. Neuveut, and M. A. Buendia. 2005. HBV induced carcinogenesis. J Clin Virol 34(Suppl 1): S75–8.PubMedCrossRefGoogle Scholar
  32. 32.
    Murakami, Y., K. Saigo, H. Takashima, et al. 2005. Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 54(8):1162–8.PubMedCrossRefGoogle Scholar
  33. 33.
    Minami, M., Y. Daimon, K. Mori, et al. 2005. Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis. Oncogene 24(27):4340–8.PubMedCrossRefGoogle Scholar
  34. 34.
    Hsu, T., T. Moroy, J. Etiemble, et al. 1988. Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma. Cell 55:627–35.PubMedCrossRefGoogle Scholar
  35. 35.
    Moroy, T., A. Marchio, J. Etiemble, et al. 1986. Rearrangement and enhanced expression of c-myc in hepatocellular carcinoma of hepatitis virus infected woodchucks. Nature 324:276–9.PubMedCrossRefGoogle Scholar
  36. 36.
    Fourel, G., C. Trepo, L. Bougueleret, et al. 1990. Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature 347(6290):294–8.PubMedCrossRefGoogle Scholar
  37. 37.
    Dejean, A., L. Bougueleret, K. H. Grzeschik, et al. 1986. Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma. Nature 322:70–2.PubMedCrossRefGoogle Scholar
  38. 38.
    Wang, J., X. Chenivesse, B. Henglein, et al. 1990. Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma. Nature 343(6258):555–7.PubMedCrossRefGoogle Scholar
  39. 39.
    Benhamou, Y., M. Bochet, V. Di Martino, et al. 1999. Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients. The Multivirc Group. Hepatology 30(4):1054–8.PubMedCrossRefGoogle Scholar
  40. 40.
    Colin, J. F., D. Cazals-Hatem, M. A. Loriot, et al. 1999. Influence of human immunodeficiency virus infection on chronic hepatitis B in homosexual men. Hepatology 29(4):1306–10.PubMedCrossRefGoogle Scholar
  41. 41.
    Weinig, M., J. G. Hakim, I. Gudza, et al. 1997. Hepatitis C virus and HIV antibodies in patients with hepatocellular carcinoma in Zimbabwe: A pilot study. Trans R Soc Trop Med Hyg 91(5):570–2.PubMedCrossRefGoogle Scholar
  42. 42.
    Tswana, S. A., and S. R. Moyo. 1992. The interrelationship between HBV-markers and HIV antibodies in patients with hepatocellular carcinoma. J Med Virol 37(3):161–4.PubMedCrossRefGoogle Scholar
  43. 43.
    Sherman, M. 2006. Optimizing management strategies in special patient populations. Am J Gastroenterol 101(Suppl 1):S26–31.PubMedCrossRefGoogle Scholar
  44. 44.
    Puoti, M., R. Bruno, V. Soriano, et al. 2004. Hepatocellular carcinoma in HIV-infected patients: Epidemiological features, clinical presentation and outcome. AIDS 18(17):2285–93.PubMedCrossRefGoogle Scholar
  45. 45.
    Kramer, J. R., T. P. Giordano, J. Souchek, et al. 2005. The effect of HIV coinfection on the risk of cirrhosis and hepatocellular carcinoma in U.S. veterans with hepatitis C. Am J Gastroenterol 100(1):56–63.PubMedCrossRefGoogle Scholar
  46. 46.
    Giordano, T. P., J. R. Kramer, J. Souchek, et al. 2004. Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis C virus: A cohort study, 1992–2001. Arch Intern Med 164(21):2349–54.PubMedCrossRefGoogle Scholar
  47. 47.
    Garcia-Samaniego, J., M. Rodriguez, J. Berenguer, et al. 2001. Hepatocellular carcinoma in HIV-infected patients with chronic hepatitis C. Am J Gastroenterol 96(1):179–83.PubMedGoogle Scholar
  48. 48.
    Bruno, R., M. Puoti, P. Sacchi, et al. 2006. Management of hepatocellular carcinoma in human immunodeficiency virus-infected patients. J Hepatol 44(1 Suppl):S146–50.PubMedCrossRefGoogle Scholar
  49. 49.
    Smukler, A. J., and L. Ratner. 2002. Hepatitis viruses and hepatocellular carcinoma in HIV-infected patients. Curr Opin Oncol 14(5):538–42.PubMedCrossRefGoogle Scholar
  50. 50.
    Hyun, C. B., and W. J. Coyle. 2004. Hepatocellular carcinoma in a patient with human immunodeficiency virus and hepatitis B virus coinfection: An emerging problem? South Med J 97(4):401–6.PubMedCrossRefGoogle Scholar
  51. 51.
    Tanaka, T., A. Imamura, G. Masuda, et al. 1996. A case of hepatocellular carcinoma in HIV-infected patient. Hepatogastroenterology 43(10):1067–72.PubMedGoogle Scholar
  52. 52.
    Chen, C. J., H. I. Yang, J. Su, et al. 2006. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295(1):65–73.PubMedCrossRefGoogle Scholar
  53. 53.
    Ohata, K., K. Hamasaki, K. Toriyama, et al. 2004. High viral load is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis B virus infection. J Gastroenterol Hepatol 19(6):670–5.PubMedCrossRefGoogle Scholar
  54. 54.
    Hu, J., and D. Nguyen. 2004. Therapy for chronic hepatitis B: The earlier, the better? Trends Microbiol 12(10):431–3.PubMedCrossRefGoogle Scholar
  55. 55.
    van Zonneveld, M., P. Honkoop, B. E. Hansen, et al. 2004. Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B. Hepatology 39(3):804–10.PubMedCrossRefGoogle Scholar
  56. 56.
    Akuta, N., F. Suzuki, Y. Suzuki, et al. 2005. Favorable efficacy of long-term lamivudine therapy in patients with chronic hepatitis B: An 8-year follow-up study. J Med Virol 75(4):491–8.PubMedCrossRefGoogle Scholar
  57. 57.
    Liaw, Y. F., J. J. Sung, W. C. Chow, et al. 2004. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 351(15):1521–31.PubMedCrossRefGoogle Scholar
  58. 58.
    Matsumoto, A., E. Tanaka, A. Rokuhara, et al. 2005. Efficacy of lamivudine for preventing hepatocellular carcinoma in chronic hepatitis B: A multicenter retrospective study of 2795 patients. Hepatol Res.Google Scholar
  59. 59.
    Shindo, M., K. Hamada, Y. Oda, et al. 2001. Long-term follow-up study of sustained biochemical responders with interferon therapy. Hepatology 33(5):1299–302.PubMedCrossRefGoogle Scholar
  60. 60.
    Tsuda, N., N. Yuki, K. Mochizuki, et al. 2004. Long-term clinical and virological outcomes of chronic hepatitis C after successful interferon therapy. J Med Virol 74(3):406–13.PubMedCrossRefGoogle Scholar
  61. 61.
    Meuleman, P., L. Libbrecht, S. Wieland, et al. 2006. Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus. J Virol 80(6):2797–807.PubMedCrossRefGoogle Scholar
  62. 62.
    Yoon, E. J., and K. Q. Hu. 2006. Hepatitis C virus (HCV) infection and hepatic steatosis. Int J Med Sci 3(2):53–6.PubMedGoogle Scholar
  63. 63.
    Gaslightwala, I., and E. J. Bini. 2006. Impact of human immunodeficiency virus infection on the prevalence and severity of steatosis in patients with chronic hepatitis C virus infection. J Hepatol.Google Scholar
  64. 64.
    Altavilla, G., A. Caputo, M. Lanfredi, et al. 2000. Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene. Am J Pathol 157(4):1081–9.PubMedGoogle Scholar
  65. 65.
    Pol, S., P. Lebray, and A. Vallet-Pichard. 2004. HIV infection and hepatic enzyme abnormalities: Intricacies of the pathogenic mechanisms. Clin Infect Dis 38(Suppl 2):S65–72.PubMedCrossRefGoogle Scholar
  66. 66.
    Stapleton, J. T., C. F. Williams, and J. Xiang. 2004. GB virus type C: A beneficial infection? J Clin Microbiol 42(9):3915–9.PubMedCrossRefGoogle Scholar
  67. 67.
    Berzsenyi, M. D., D. S. Bowden, and S. K. Roberts. 2005. GB virus C: Insights into co-infection. J Clin Virol 33(4):257–66.PubMedCrossRefGoogle Scholar
  68. 68.
    Xiang, J., S. Wunschmann, D. J. Diekema, et al. 2001. Effect of coinfection with GB virus C on survival among patients with HIV infection. N Engl J Med 345(10):707–14.PubMedCrossRefGoogle Scholar
  69. 69.
    Tillmann, H. L., H. Heiken, A. Knapik-Botor, et al. 2001. Infection with GB virus C and reduced mortality among HIV-infected patients. N Engl J Med 345(10):715–24.PubMedCrossRefGoogle Scholar
  70. 70.
    Xiang, J., S. L. George, S. Wunschmann, et al. 2004. Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1. Lancet 363(9426):2040–6.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Jianming Hu
    • 1
  • Laurie Ludgate
    • 2
  1. 1.Department of Microbiology and ImmunologyThe Pennsylvania State University College of MedicineHershey
  2. 2.Department of Microbiology and ImmunologyThe Pennsylvania State University College of MedicineHershey

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